GlpBio

Signaling Pathways

Signaling Pathways(信号通路)

研究方向

Signaling Pathways 相关产品(35130)

  • GC12991 structure
    GC12991EB 47
    CAS: 366454-36-6
    纯度: >99.50%

    A PARP1 and TNKS2 inhibitor

  • GC12993 structure
    GC12993Vancomycin hydrochloride
    CAS: 1404-93-9
    纯度: >99.50% / >98.00%

    A glycopeptide antibiotic

  • GC12994 structure
    GC12994Rivastigmine Tartrate
    CAS: 129101-54-8
    纯度: >99.00%

    A cholinesterase inhibitor

  • GC12998 structure
    GC12998HIV-1 integrase inhibitor
    CAS: 544467-07-4

    HIV-1整合酶抑制剂可用于抗HIV。

  • GC13000 structure
    GC13000Acebutolol HCl
    CAS: 34381-68-5
    纯度: >98.00% / >99.50%

    A β 1 -AR antagonist

  • GC13003 structure
    GC13003AMG-517
    CAS: 659730-32-2
    纯度: >99.50%

    A TRPV1 antagonist

  • GC13004 structure
    GC13004ML161
    CAS: 423735-93-7
    纯度: >98.00%

    Reversible inhibitor of PAR1-mediated platelet activation

  • GC13012 structure
    GC13012Motesanib
    CAS: 453562-69-1
    纯度: >99.50% / >98.00%

    Motesanib (AMG 706) 是一种有效的 ATP 竞争性 VEGFR1/2/3 抑制剂，IC50 分别为 2 nM/3 nM/6 nM，对 Kit 具有相似的活性，对 VEGFR 的选择性比对 VEGFR 的选择性高约 10 倍PDGFR 和 Ret。

  • GC13015 structure
    GC13015LDN-27219
    CAS: 312946-37-5
    纯度: >99.50% / >98.00%

    An inhibitor of TG2

  • GC13016 structure
    GC13016Safinamide
    CAS: 133865-89-1
    纯度: >99.50%

    Safinamide 是一种强效、选择性和可逆的单胺氧化酶 B (MAO-B) 抑制剂 (IC50=0.098 μM)，优于 MAO-A (IC50=580 μM)。

  • GC13018 structure
    GC13018IOX2(Glycine)
    CAS: 931398-72-0
    纯度: >99.50%

    A selective PHD2 inhibitor

  • GC13022 structure
    GC13022Esomeprazole Magnesium trihydrate
    CAS: 217087-09-7

    An H + /K + -ATPase inhibitor

  • GC13028 structure
    GC13028SB 415286
    CAS: 264218-23-7
    纯度: >99.50%

    A selective inhibitor of GSK-3

  • GC13029 structure
    GC13029AZD2014
    CAS: 1009298-59-2
    纯度: >98.50%

    A potent dual mTORC1/2 inhibitor

  • GC13030 structure
    GC13030(R)-(-)-Ibuprofen
    CAS: 51146-57-7
    纯度: >99.50%

    A less potent enantiomer of ibuprofen

  • GC13031 structure
    GC13031Trifluoperazine 2HCl
    CAS: 440-17-5
    纯度: >99.00% / >98.00%

    An anti-adrenergic and anti-dopaminergic agent

  • GC13035 structure
    GC13035Bay 11-7821
    CAS: 19542-67-7
    纯度: >99.50% / >95.00%

    Bay 11-7821是一种IκBα磷酸化和NF-κB抑制剂，选择性且不可逆地抑制TNF-α诱导的IκB-α磷酸化（IC 50 值约为10μM），并减少NF-κB和粘附分子的表达。Bay 11-7821抑制泛素特异性蛋白酶USP7和USP21，IC 50 分别为0.19、0.96μM。

  • GC13040 structure
    GC13040TRAM-34
    CAS: 289905-88-0
    纯度: >99.50%

    An IKCa1/K Ca 3.1 channel blocker

  • GC13044 structure
    GC1304417-DMAG (Alvespimycin) HCl
    CAS: 467214-21-7
    纯度: >98.00%

    17-DMAG (Alvespimycin) HCl是一种有效的Hsp90的抑制剂，其IC 50 值为62nM。

  • GC13045 structure
    GC13045Tyrphostin AG 1296
    CAS: 146535-11-7
    纯度: >99.00%

    An inhibitor of PDGF receptor kinase

  • GC13053 structure
    GC13053Pizotifen
    CAS: 15574-96-6
    纯度: >98.00%

    A triptan

  • GC13055 structure
    GC13055Mocetinostat (MGCD0103, MG0103)
    CAS: 726169-73-9
    纯度: >99.00%

    An orally available HDAC inhibitor

  • GC13056 structure
    GC13056CX-6258
    CAS: 1202916-90-2
    纯度: >99.50%

    A pan-Pim kinase inhibitor

  • GC13066 structure
    GC13066Y-320
    CAS: 288250-47-5
    纯度: >99.00%

    An inhibitor of IL-15-mediated CD4 T cell activation