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Home >> Signaling Pathways >> Cell Cycle/Checkpoint >> G2/M

G2/M

  1. Cat.No. 产品名称 Information
  2. GC91899 Carmustine-d8

    BCNU-d8; bis-Chloroethylnitrosourea-d8

     Carmustine-d8旨在用作气相色谱或液相色谱-质谱定量卡莫司汀的内标。
  3. GC91228 SSE1806

    一种微管不稳定剂
  4. GC91096 S-72

    一种微管聚合抑制剂。
  5. GC90366 Dolastatin 15 (trifluoroacetate salt)

    NSC 617668

    一种具有抗癌活性的肽。
  6. GC52293 STAT3 Inhibitor 4m

    Signal Transducer and Activator of Transcription 3 Inhibitor 4m

     A STAT3 inhibitor
  7. GC49773 Albendazole sulfone-d3

    阿苯哒唑砜-D3

     An internal standard for the quantification of albendazole sulfone
  8. GC62777 2-Methoxy-4-vinylphenol

    4-乙烯基-2-甲氧基苯酚

     2-Methoxy-4-vinylphenol (2M4VP) 是天然的发芽抑制剂，具有抗炎活性。
  9. GC49412 NSC 756093 An inhibitor of the GBP1-Pim-1 protein-protein interaction
  10. GC49077 Podophyllotoxin-d6

    PPT-d6

     An internal standard for the quantification of podophyllotoxin and picropodophyllotoxin
  11. GC49015 Phenethyl isothiocyanate

    2-苯基乙基异硫代氰酸酯

     An isothiocyanate with anticancer activity
  12. GC19822 SYRINGETIN

    丁香亭

     丁香素是一种类黄酮衍生物，与 BMP-2 产量增加有关。
  13. GC48848 Albendazole-d7

    阿苯达唑-D7,SKF-62979-d7

     An internal standard for the quantification of albendazole
  14. GC48688 Griseofulvin-d3

    灰黄霉素 d3

     An internal standard for the quantification of griseofulvin
  15. GC48119 Suprafenacine

    SML1493

     An inhibitor of tubulin polymerization with anticancer activity
  16. GC47803 Noscapine-13C-d3

    Narcotine-13C-d3, Opianine-13C-d3

     An internal standard for the quantification of noscapine
  17. GC47279 Echinosporin

    (-)-棘孢链菌素

     A bacterial metabolite with antibacterial and anticancer activities
  18. GC60294 Poloppin Poloppin是一种有效的细胞渗透抑制剂，可抑制有丝分裂的polo样激酶(PLK)IC50=26.9μM)，并可通过Polo-box结构域(PBD)阻止蛋白之间的相互作用(Kd=29.5μM)。Poloppin选择性地杀死表达突变KRAS的细胞，增强有丝分裂中的死亡。Poloppin可用作KRAS突变型癌症的研究，可作为单一试剂，或与c-MET抑制剂联合使用。
  19. GC39483 BO-264 A TACC3 inhibitor
  20. GC45149 VK3-OCH3

    Vitamin K3-OCH3

     An analog of vitamin K3
  21. GC44732 Protopine (hydrochloride)

    盐酸前鸦片碱

     An alkaloid with diverse biological activities
  22. GC43379 Darinaparsin

    Dimethylarsinic glutathione

     Darinaparsin是一种新型有机砷化合物，对HL-60、Jurkat及HepG2、A549的IC₅₀为0.5–3.0µM，目前用于复发/难治性淋巴瘤及实体瘤的临床前与临床研究。
  23. GC43239 Chk2 Inhibitor

    SC-203885

     A Chk2 inhibitor
  24. GC42997 Butyrolactone I

    丁酸内酯I,Olomoucin

     Butyrolactone I是具有口服活性的由A. terreus产生的细胞周期蛋白依赖性激酶1（CDK1）的ATP竞争性抑制剂（在PC-14细胞中对cdc2 激酶的IC50值为20μg/ml）。
  25. GC42933 Binucleine 2 An inhibitor of Drosophila Aurora B kinase
  26. GC42616 7-oxo Staurosporine

    BMY 41950, RK-1409

     An antibiotic with diverse biological activities
  27. GC41564 MPT0B014 An inhibitor of tubulin polymerization
  28. GC41563 Globosuxanthone A A fungal metabolite
  29. GC41305 DA-3003-2

    NSC 663285

     A Cdc25 phosphatase inhibitor
  30. GC41186 Malformin C

    畸形素C

     A natural bicyclic pentapeptide
  31. GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone

    2,3-二甲氧基-5-甲基-1,4-苯醌,CoQ0

     An intermediate in the synthesis of ubiquinones that has anticancer activity
  32. GC18909 KRIBB3 An Hsp7 and inhibitor of microtubule polymerization
  33. GC18666 Debromohymenialdisine

    DBH, SKF 108753

     An inhibitor of Chk1 and Chk2
  34. GC18353 Prostaglandin A2

    前列腺素A2,Medullin

     A naturally occurring prostaglandin with antiviral/antitumor activity
  35. GC18278 NU 6102

    4-[[6-(环己基甲氧基)-1H-嘌呤-2-基]氨基]苯磺酰胺

     NU 6102是一种强效的CDK1和CDK2抑制剂，对CDK1/cyclin B和CDK2/cyclin A3的IC50值分别为9.5nM和5.4nM。

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