SIRPB1 Human
目录号 : GP24589Recombinant Human Signal Regulatory Protein Beta 1
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SIRPB1produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (30-371 a.a.) and fused to a 6 aa His Tag at C-terminus containing a total of 348 amino acids and having a molecular mass of 38.0kDa. SIRPB1shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.
| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | SIRPB1; CD172b; SIRP-BETA-1; SIRP-Beta-1 Isoform 3; CD172b Antigen; CD172b. | ||
| Amino Acid Sequence | EDELQVIQPE KSVSVAAGES ATLRCAMTSL IPVGPIMWFR GAGAGRELIY NQKEGHFPRV TTVSELTKRN NLDFSISISN ITPADAGTYY CVKFRKGSPD DVEFKSGAGT ELSVRAKPSA PVVSGPAVRA TPEHTVSFTC ESHGFSPRDI TLKWFKNGNE LSDFQTNVDP AGDSVSYSIH STARVVLTRG DVHSQVICEI AHITLQGDPL RGTANLSEAI RVPPTLEVTQ QPMRAENQAN VTCQVSNFYP RGLQLTWLEN GNVSRTETAS TLIENKDGTY NWMSWLLVNT CAHRDDVVLT CQVEHDGQQA VSKSYALEIS AHQKEHGSDI THEAALAPTA PLHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | SIRPB1protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) & 10% glycerol. | ||
Signal-regulatory protein beta-1 isoform 1 or SIRPB1, is an immunoglobulin-like cell surface receptor which is a part of the SIRP superfamily. SIRPB1 is a cell membrane receptor that takes part in the negative regulation of tyrosine kinase-coupled signaling pathway. SIRPB1 is engaged in the activation of tyrosine kinase SYK, SIRP alpha molecules (activates SHP-1 and SHP-2 protein tyrosine phosphatases), etc.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.