Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC46943 Boscalid

啶酰菌胺
A broad-spectrum carboxamide fungicide
GC40009 Bostrycin

Rhodosporin
An anthraquinone with diverse biological activities
GC46946 BPC 157 (acetate)

GEPPPGKPADDAGLV, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
A pentadecapeptide with diverse biological activities
GC42969 bpV(phen) (potassium hydrate)

Bisperoxovanadium(phen), Potassium Bisperoxo(1,10phenanthroline) oxovanadate (V)
An inhibitor of phosphatases
GC62128 Bractoppin Bractoppin 是一种串联 BRCT（串联 BRCT，BRCA1），由人乳腺癌和卵巢癌抑制蛋白 (BRCA1) tBRCT 结构域识别磷酸肽的药物样抑制剂，在体外选择性抑制底物结合的纳摩尔活性，IC50 为0.074 77777#181;M。
GC48901 BRD9876

6-叔丁基-2,3-二氰基萘
An Eg5 inhibitor
GC49740 Brevetoxin 3

PbTx-3
A neurotoxin
GC46949 Bromacil

除草定
An herbicide
GC12001 BS-181

N5-(6-氨基己基)-3-异丙基-N7-苄基吡唑并[1,5-A]嘧啶-5,7-二胺,BS 181; BS181
A selective Cdk7 inhibitor
GC13690 BS-181 HCl A selective Cdk7 inhibitor
GC33149 BTB-1

4-氯-2-甲基苯基硫氰酸酯
A reversible Kif18A inhibitor
GC46104 Butyric Acid-d7

氘代丁酸(D7),Butanoic acid-d7
An internal standard for the quantification of sodium butyrate
GC42997 Butyrolactone I

丁酸内酯I,Olomoucin
A Cdk1 inhibitor
GC45394 Bz-IEGR-pNA (acetate)

Bz-Ile-Glu-Gly-Arg-pNA, Bz-Ile-Glu-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate
A colorimetric Factor Xa substrate
GC40708 C2 L-erythro Ceramide (d18:1/2:0)

L-erythro Cer(d18:1/2:0), L-erythro Ceramide (d18:1/2:0), N-acetyl-L-erythro-Sphingosine
A bioactive sphingolipid
GC40709 C2 L-threo Ceramide (d18:1/2:0)

L-threo Cer(d18:1/2:0), L-threo Ceramide (d18:1/2:0), N-acetyl-L-threo-Sphingosine
A bioactive sphingolipid
GC45616 C6 Urea Ceramide

C6 Ceramide (d18:1/6:0) Urea, Cer(d18:1/6:0) Urea, D-erythro-Urea-C6-Ceramide
An inhibitor of neutral ceramidase
GC11765 Cabazitaxel

卡巴他赛,XRP6258; RPR-116258A; taxoid XRP6258
A semisynthetic taxane
GC65575 Cabazitaxel-d6

卡巴他赛-D6,XRP6258-d6; RPR-116258A-d6; taxoid XRP6258-d6
Cabazitaxel-d6 (XRP6258-d6) 是 Cabazitaxel 的氘代物。Cabazitaxel 是天然紫杉烷脱乙酰基巴卡丁III 的半合成衍生物，具有显著的抗肿瘤功效。
GC45395 Cabazitaxel-d9

XRP6258-d9; RPR-116258A-d9; taxoid XRP6258-d9
An internal standard for the quantification of cabazitaxel
GC47018 Cacodylic Acid (sodium salt hydrate)

二甲砷酸钠三水合物
A reagent used in electron microscopy techniques
GC18315 Calpain Inhibitor VI

SJA6017
A calpain and cathepsin inhibitor
GC65935 CAM833 CAM833是一种亚微摩尔化学抑制剂，可抑制肿瘤抑制因子BRCA2的RAD51重组酶和BRC重复基序之间的调节蛋白相互作用。
GC43135 Cambendazol

坎苯达唑
An anthelmintic agent
GC47022 Camostat-d6 (hydrochloride) A neuropeptide with diverse biological activities
GC74519 Cantuzumab ravtansine

IMGN242; huC242-DM4
Cantuzumab ravtansine（IMGN242；huC242-DM4）是一种ADC，是一种人源化单克隆抗体huC242，通过二硫键共价连接到DM4（DM4）。
GC19762 Capsanthin (75%)

辣椒红
A carotenoid with diverse biological activities
GC43139 Capsanthin (>98%)

辣椒红
A carotenoid with diverse biological activities
GC90622 Carbaethopendecine (bromide)

Mucoseptonex

一种含有季铵盐的阳离子表面活性剂，具有抗生素活性。
GC18449 Cardanol monoene

腰果酚(C15:1),Cardanol C15
An inhibitor of tyrosinase with anticancer properties
GC43144 Carfilzomib Impurity 13 (hydrochloride) A potential impurity found in commercial carfilzomib preparations
GC47042 Carfilzomib-d8

来那度胺-D8
An internal standard for the quantification of carfilzomib
GC91899 Carmustine-d8

BCNU-d₈; bis-Chloroethylnitrosourea-d₈
Carmustine-d8旨在用作气相色谱或液相色谱-质谱定量卡莫司汀的内标。
GC16692 Casin

Pirl1-related Compound 2
A Cdc42 GTPase inhibitor
GC43146 Caspase-9 Inhibitor III (trifluoroacetate salt)

Ac-LEHD-CMK
A caspase-9 inhibitor
GC52389 Caveolin-1 (82-101) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Cav-1, Caveolin-1 Scaffolding Domain Peptide, CSD, CSP, DGIWKASFTTFTVTKYWFYR-NH2
A synthetic peptide fragment of caveolin-1
GC43150 CAY10406 A trifluoromethyl analog of a selective caspase inhibitor
GC43154 CAY10443

(S)Indan1yl 3,4dichlorobenzylcarbamate
A cytochrome c-dependent inducer of apoptosis
GC40795 CAY10503 A proapoptotic, antiproliferative compound
GC41253 CAY10554

BML259
A potent inhibitor of Cdk5 and Cdk2
GC43184 CAY10622 A ROCK1 and ROCK2 inhibitor
GC41317 CAY10625 An inhibitor of survivin - Smac/DIABLO interaction
GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).
GC43206 CAY10732
CAY10732是一种检测一氧化碳的荧光探针。
GC45405 CAY10737 A turn-on fluorescent probe for carbon monoxide
GC52245 CAY10792 An anticancer agent
GC33300 CCB02 CCB02是一种选择性的CPAP-tubulin相互作用抑制剂，能够与tubulin结合，竞争β-tubulin的CPAP结合位点，IC50值为689nM，具有高效抗肿瘤活性。CCB02对其他的蛋白没有抑制作用，包括与细胞周期、中心体相关蛋白，同时对AuroraA，Plk1，Plk2，CDK2和CHK1的磷酸化状态无作用。
GC14986 CCG-100602 A Rho/MKL1 transcriptional pathway inhibitor
GC12795 CCG-1423 An inhibitor of Rho-mediated cell signalling
GC38898 CCG-222740 CCG-222740 is a Rho/MRTF pathway inhibitor. CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin(α-SMA) expression.