Cell Cycle/Checkpoint
Cell Cycle/Checkpoint(细胞周期/检查点)
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more
- ATM/ATR(29)
- Aurora Kinase(58)
- Cdc42(4)
- Cdc7(3)
- Chk(14)
- c-Myc(27)
- CRM1(8)
- Cyclin-Dependent Kinases(77)
- E1 enzyme(1)
- G-quadruplex(12)
- Haspin(6)
- HMTase(1)
- Kinesin(27)
- Ksp(4)
- Microtubule/Tubulin(257)
- Mps1(15)
- Mitotic(7)
- RAD51(13)
- ROCK(74)
- Rho(13)
- PERK(11)
- PLK(43)
- PTEN(6)
- Wee1(9)
- PAK(25)
- Arp2/3 Complex(8)
- Dynamin(14)
- ECM & Adhesion Molecules(54)
- Cytoskeleton & Motor Proteins(65)
- Endomembrane System & Vesicular Trafficking(36)
- G1(51)
- Genotoxic Stress(23)
- G2/M(40)
- G2/S(17)
- Inositol Phosphates(67)
- Proteolysis(183)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(1)
- MARK(3)
- NEKs(1)
Cell Cycle/Checkpoint 相关产品(1379)
- GC40702α-D-Galactopyranosylphenyl isothiocyanateCAS: 120967-92-2纯度: >98.00%
Used in neoglycoprotein preparation
- GC40901IsogarcinolCAS: 71117-97-0纯度: >95.00% / >97.00%
Isogarcinol是一种从藤黄属植物中提取的多异戊烯基取代的苯甲酮类天然化合物，Isogarcinol还是有效的乙酰胆碱酯酶（AChE；IC 50 =1.13μM）和丁酰胆碱酯酶（BChE；IC 50 =8.30μM）抑制剂。
- GC409472,3-Dimethoxy-5-methyl-p-benzoquinoneCAS: 605-94-7纯度: >98.00%
An intermediate in the synthesis of ubiquinones that has anticancer activity
- GC41242Acridine OrangeCAS: 494-38-2纯度: >75.00%
Acridine Orange是一种可穿透细胞的核酸选择性荧光染料， Acridine Orange可与DNA或RNA结合时产生荧光，与双链DNA结合时产生绿色荧光（激发光为488nm；发射光为530nm绿色荧光）。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC40663 | Corynecin V | 40958-12-1 | >98.00% | |
A chloramphenicol-like bacterial metabolite | ||||
| GC40664 | Colcemid | 477-30-5 | >98.00% / >99.00% / >99.50% | |
Colcemid是一种细胞骨架抑制剂，可以在哺乳动物细胞或卵母细胞中诱导G2/M期的有丝分裂停滞或囊泡破裂（GVBD）期的减数分裂停滞。 | ||||
| GC40667 | Aurora Kinase Inhibitor II | 331770-21-9 | >99.00% | |
Blocks Aurora A kinase activity | ||||
| GC40675 | 2-deoxy-Artemisinin | 72826-63-2 | >98.00% | |
An inactive metabolite of artemisinin | ||||
| GC40702 | α-D-Galactopyranosylphenyl isothiocyanate | 120967-92-2 | >98.00% | |
Used in neoglycoprotein preparation | ||||
| GC40708 | C2 L-erythro Ceramide (d18:1/2:0) | 150338-90-2 | >98.00% | |
A bioactive sphingolipid | ||||
| GC40709 | C2 L-threo Ceramide (d18:1/2:0) | 143615-69-4 | >98.00% | |
A bioactive sphingolipid | ||||
| GC40758 | Gly-Phe-β-naphthylamide | 21438-66-4 | >95.00% / >98.00% | |
A cathepsin C substrate | ||||
| GC40793 | L-erythro Sphinganine (d18:0) | 6036-76-6 | >98.00% | |
A bioactive sphingolipid | ||||
| GC40795 | CAY10503 | 890854-82-7 | >98.00% | |
A proapoptotic, antiproliferative compound | ||||
| GC40802 | (±)12(13)-DiHOME | 263399-35-5 | >98.00% | |
A diol form of (±)12,13-EpOME | ||||
| GC40844 | 9-(2,2-Dicyanovinyl)julolidine | 58293-56-4 | >95.00% | |
A fluorogenic dye | ||||
| GC40890 | CAY10701 | 1616967-52-2 | >98.00% | |
CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). | ||||
| GC40901 | Isogarcinol | 71117-97-0 | >95.00% / >97.00% | |
Isogarcinol是一种从藤黄属植物中提取的多异戊烯基取代的苯甲酮类天然化合物，Isogarcinol还是有效的乙酰胆碱酯酶（AChE；IC 50 =1.13μM）和丁酰胆碱酯酶（BChE；IC 50 =8.30μM）抑制剂。 | ||||
| GC40947 | 2,3-Dimethoxy-5-methyl-p-benzoquinone | 605-94-7 | >98.00% | |
An intermediate in the synthesis of ubiquinones that has anticancer activity | ||||
| GC41110 | 16-epi Latrunculin B | 444911-05-1 | >95.00% | |
An actin depolymerizing macrolide | ||||
| GC41156 | 5-Octyl D-glutamate | 149332-65-0 | >98.00% | |
A cell-permeable form of D-glutamate | ||||
| GC41186 | Malformin C | 59926-78-2 | >95.00% | |
A natural bicyclic pentapeptide | ||||
| GC41242 | Acridine Orange | 494-38-2 | >75.00% | |
Acridine Orange是一种可穿透细胞的核酸选择性荧光染料， Acridine Orange可与DNA或RNA结合时产生荧光，与双链DNA结合时产生绿色荧光（激发光为488nm；发射光为530nm绿色荧光）。 | ||||
| GC41253 | CAY10554 | 267654-00-2 | >98.00% | |
A potent inhibitor of Cdk5 and Cdk2 | ||||
| GC41258 | Spiroxamine | 118134-30-8 | >95.00% | |
A fungicide | ||||
| GC41268 | (E)-2-Hexadecenal | 22644-96-8 | >95.00% | |
A long-chain fatty aldehyde | ||||
| GC41272 | Lateropyrone | 93752-78-4 | >99.00% | |
A fungal metabolite | ||||
| GC41304 | Deoxybrevianamide E | 34610-68-9 | >99.00% | |
A fungal metabolite | ||||