Anti-Mouse IL-1a Antibody (ALF-161) 是一种抗小鼠 IL-1a IgG1 单克隆抗体。
Sample solution is provided at 25 µL, 10mM.
Anti-Mouse IL-1a Antibody (ALF-161) is an anti-mouse IL-1a IgG1 monoclonal antibody. Anti-Mouse IL-1a Antibody (ALF-161) can inhibit CD8+ T cell response by blocking IL-1a signaling. Anti-Mouse IL-1a Antibody (ALF-161) can reversibly transform myeloid cell expansion and improve T cell function. Anti-Mouse IL-1a Antibody (ALF-161) can be used for researches on immune response and cancer such as breast cancer[1][2].
References:
[1]. Kumar SRP, et al. TLR9-independent CD8+ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling. Mol Ther. 2024 Feb 7;32(2):325-339.
[2]. Allen BM, et al. Systemic dysfunction and plasticity of the immune macroenvironment in cancer models. Nat Med. 2020 Jul;26(7):1125-1134.
Anti-Mouse IL-1a Antibody (ALF-161) 是一种抗小鼠 IL-1a IgG1 单克隆抗体。Anti-Mouse IL-1a Antibody (ALF-161) 可以通过阻断 IL-1a 信号传导来抑制 CD8+ T 细胞反应。Anti-Mouse IL-1a Antibody (ALF-161) 可以逆转髓系细胞扩增并改善 T 细胞功能。Anti-Mouse IL-1a Antibody (ALF-161) 可用于免疫应答和癌症如乳腺癌的研究。
| Cas No. | SDF | ||
| 分子式 | 分子量 | 150 kDa | |
| 溶解度 | 储存条件 | Please store the product under the recommended conditions in the Certificate of Analysis. | |
| Shipping Condition | 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
![]() |
1 mg | 5 mg | 10 mg |
| 1 mM | 6.7 μL | 33.3 μL | 66.7 μL |
| 5 mM | 1.3 μL | 6.7 μL | 13.3 μL |
| 10 mM | 0.7 μL | 3.3 μL | 6.7 μL |
| 第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
| 给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
| 第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Quality Control & SDS
- View current batch:
- Purity: >95.00% Appearance: A liquid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
















