Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC15712 Y-27632 A ROCK inhibitor
GC10512 Y-27632 dihydrochloride

y-27632, Y27632, Y-27632 dihydrochloride, Y 27632
Y-27632 dihydrochloride 作为一种选择性 Rho 激酶抑制剂，是一种新型支气管扩张剂。
GC37947 Y-33075

(R)-4-(1-氨基乙基)-N-1H-吡咯并[2,3-B]吡啶-4-基苯甲酰胺,Y 39983
An inhibitor of ROCK2
GC13423 Y-39983 dihydrochloride ROCK family inhibitor
GC18578 YK-3-237 An inhibitor of tubulin polymerization and activator of SIRT1
GC45175 YVAD-CHO (trifluoroacetate salt)

H-Tyr-Val-Ala-Asp-CHO
A caspase-1/ICE inhibitor
GC48471 Z-(L-Arg)-AMC (hydrochloride)

Z-L-精氨酸-7-胺基-4-甲基香豆素盐酸盐
A fluorogenic substrate for trypsin, cathepsin B, and cathepsin H
GC45177 Z-AEVD-FMK

Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone
A caspase-10 inhibitor
GA23742 Z-D-Arg-Gly-Arg-pNA . 2 HCl

Z-D-ARG-GLY-ARG-PNA二盐酸盐
A colorimetric Factor Xa substrate
GC13859 Z-DEVD-AFC

Caspase-3 Fluorogenic Substrate IV
A caspase-3 fluorogenic substrate
GC45178 Z-DEVD-CMK (trifluoroacetate salt)

Z-Asp-Glu-Val-Asp-CMK
An irreversible protease inhibitor
GC49145 Z-FR-AMC (trifluoroacetate salt)

Z-FR-7-amino-4-Methylcoumarin, Z-Phe-Arg-AMC
A fluorogenic substrate for cathepsin L
GC45181 Z-IETD-AFC

Z-异亮氨酰-谷氨酰-苏氨酰-天冬氨酸-AFC
A fluorogenic substrate for caspase-8 and granzyme B
GC48390 Z-LRGG-AMC (trifluoroacetate salt)

Z-Leu-Arg-Gly-Gly-AMC, Z-Leu-Arg-Gly-Gly-7-amino-4-methylcoumarin
A fluorogenic substrate for isopeptidase T
GC45599 Z-Phe-Tyr(tBu)-diazomethylketone

Cbz-Phe-Tyr(O-t-Bu)-CHN2, Z-Phe-Tyr(tBu)-CHN2
An inhibitor of cathepsin L
GC40125 Z-VA-DL-D(OMe)-FMK (trifluoroacetate salt)

Caspase-1 Inhibitor V, Z-VAD-FMK, Z-VAD(OMe)-FMK, Z-Val-Ala-DL-Asp(OMe)-Fluoromethyl Ketone
A pan-caspase inhibitor
GC40151 Z-VAD-AMC (acetate)

Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin
A caspase-1 fluorogenic substrate
GC45190 Z-VDVAD-AFC (trifluoroacetate salt)

Z-Val-Asp-Val-Ala-Asp-AFC, Z-Val-Asp-Val-Ala-Asp-7-amino-4-trifluormethylcoumarin
A fluorogenic substrate for caspase-2
GC45191 Z-VDVAD-pNA (trifluoroacetate salt)

Z-VDVAD-p-nitroanilide, Z-Val-Asp-Val-Ala-Asp-pNA, Z-Val-Asp-Val-Ala-Asp-p-nitroanilide
A colorimetric caspase-2 substrate
GC40150 Z-VEID-AFC (trifluoroacetate salt)

Z-Val-Glu-Ile-Asp-AFC, Z-Val-Glu-Ile-Asp-7-amino-4-trifluormethylcoumarin
A fluorogenic substrate for caspase-6
GC40153 Z-YVAD-AFC (trifluoroacetate salt)

Z-Tyr-Val-Ala-Asp-AFC, Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-7-amino-4-trifluoromethylcoumarin
A fluorogenic substrate for caspase-1
GC45193 Z-YVAD-CMK (trifluoroacetate salt)

Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone, Caspase-1 Inhibitor IV
An inhibitor of caspase-1 and caspase-3
GC40119 Z-YVADLD-FMK (trifluoroacetate salt)

Z-Tyr-Val-Ala-Asp-Leu-Asp-FMK
A peptide
GC70163 Zagotenemab

LY33003560
Zagotenemab (LY3303560) 是一种人源化抗 tau 抗体，能选择性地结合和中和大脑中的 tau 沉积物。Zagotenemab 可用于阿尔兹海默症的研究。
GC12470 ZCL278 A selective Cdc42 inhibitor
GC71056 Zelasudil Zelasudil是Rho相关（ROCK）激酶抑制剂。
GC33120 ZINC00881524 A ROCK inhibitor
GC14409 ZM 447439 Selective inhibitor of Aurora B kinase
GC62697 ZN-c3 ZN-c3 is an oral active, highly effective and selective Wee1 inhibitor with IC50 of 3.9 nM, which can be used in cancer research.
GC14701 Zoledronic Acid

唑来膦酸; Zoledronate; CGP 42446; CGP42446A; ZOL 446
A bisphosphonate that inhibits bone resorption
GC40044 Zymostenol

Δ8-Cholesterol
A precursor of cholesterol