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Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

研究方向

Neuroscience 相关产品(3932)

  • GC39705 structure
    GC39705Dehydroaripiprazole
    CAS: 129722-25-4
    纯度: >97.00%

    Dehydroaripiprazole (OPC-14857) 是 Aripiprazole 的活性代谢产物。Aripiprazole 是一种抗精神病药，被 CYP3A4 和 CYP2D6 代谢，主要形成 Dehydroaripiprazole。Dehydroaripiprazole 具有与 Aripiprazole 同等的抗精神病活性。

  • GC39724 structure
    GC39724Quetiapine D4 hemifumarate
    CAS: 1217310-65-0

    Quetiapine D4 hemifumarate 是 Quetiapine hemifumarate 的氘代物。Quetiapine 是一种 5-HT 受体激动剂，也是一种多巴胺受体 (dopamine receptor) 拮抗剂。具有抗抑郁和抗焦虑作用。

  • GC39735 structure
    GC39735Triprolidine hydrochloride monohydrate
    CAS: 6138-79-0
    纯度: >99.50%

    Triprolidine Hydrochloride is the hydrochloride salt form of Triprolidine, which is the first generation histamine H1 antagonist used in allergic rhinitis.

  • GC39736 structure
    GC39736Propionylpromazine hydrochloride
    CAS: 7681-67-6
    纯度: >99.00%

    A promazine neuroleptic and dopamine receptor antagonist

  • GC39748 structure
    GC39748Facinicline hydrochloride
    CAS: 677305-02-1
    纯度: >99.50%

    Facinicline hydrochloride (RG3487 hydrochloride) 是具有口服活性的烟碱 α7 receptor 部分激动剂，对人nAChR 的 Ki 值为 6 nM。Facinicline hydrochloride (RG3487 hydrochloride) 可改善啮齿类动物的认知和感觉运动门控。Facinicline hydrochloride (RG3487 hydrochloride) 对5-HT3 受体 (拮抗剂)的Ki 值为 1.2 nM。

  • GC39752 structure
    GC39752ML417
    CAS: 1386162-69-1
    纯度: >99.50%

    ML417 是一种选择性的，可透过血脑屏障的 D3 多巴胺受体 (D3R) 激动剂，EC50 为 38 nM。ML417 促进 D3R 介导的 β-arrestin 易位、G 蛋白介导的信号传导和 pERK 磷酸化，对其他 GPCR 介导的信号传导影响最小。ML417 对毒素诱导的多巴胺能神经元变性具有神经保护作用。

  • GC39757 structure
    GC39757Etilevodopa hydrochloride
    CAS: 39740-30-2
    纯度: >98.50%

    Etilevodopa (L-Dopa ethyl ester) hydrochloride 是 Levodopa 的前药，在胃肠道中被非特异性酯酶快速水解为 Levodopa 和乙醇。Etilevodopa hydrochloride 用于治疗帕金森病 (PD)。Levodopa 是多巴胺的直接前体，是一种合适的前体药物，有助于中枢神经系统的渗透和传递多巴胺。

  • GC39798 structure
    GC39798Scoulerine
    CAS: 6451-73-6
    纯度: >99.00%

    A benzylisoquinoline alkaloid with diverse biological activities

  • GC39800 structure
    GC398002BAct
    CAS: 2143542-28-1
    纯度: >97.50%

    An eIF2B activator

  • GC39836 structure
    GC39836Coumaran
    CAS: 496-16-2
    纯度: >99.50%

    Coumaran (2,3-Dihydrobenzofuran) 是一种从 L. camara 中提取的 (AChE) 抑制剂。Coumaran 可以用作生物农药。

  • GC39848 structure
    GC39848Indole-2-carboxylic acid
    CAS: 1477-50-5
    纯度: >99.50%

    Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation.

  • GC40016 structure
    GC40016Ganglioside GM2 Mixture (sodium salt)
    CAS: 19600-01-2
    纯度: >98.00%

    A mixture of ganglioside G M2

  • GC40018 structure
    GC40018Donepezil N-oxide
    CAS: 120013-84-5
    纯度: >98.00%

    An active metabolite of donepezil

  • GC40024 structure
    GC40024Altenusin
    CAS: 31186-12-6
    纯度: >98.00%

    A fungal metabolite with diverse biological activities

  • GC40027 structure
    GC40027True Blue
    CAS: 71431-30-6
    纯度: >90.00%

    A fluorescent neuronal retrograde tracer

  • GC40041 structure
    GC40041Cholesteryl Lignocerate
    CAS: 73024-96-1
    纯度: >98.00%

    A cholesterol ester

  • GC40042 structure
    GC40042Cholesteryl Erucate
    CAS: 24516-39-0
    纯度: >98.00%

    A cholesterol ester

  • GC40043 structure
    GC40043Totarol
    CAS: 511-15-9
    纯度: >98.00%

    Totarol是一种非特异性细菌细胞分裂蛋白FtsZ的抑制剂。

  • GC40044 structure
    GC40044Zymostenol
    CAS: 566-97-2
    纯度: >95.00%

    A precursor of cholesterol

  • GC40045 structure
    GC400454-(Dimethylamino)-1-methylpyridinium (iodide)
    CAS: 7538-79-6
    纯度: >95.00%

    A pyridinium salt

  • GC40053 structure
    GC400535α,6α-epoxy Cholestanol
    CAS: 1250-95-9
    纯度: >95.00%

    5α,6α-epoxy Cholestanol 是一种胆固醇衍生物，可以通过线粒体中的细胞色素P450酶系催化生成或是在脂质过氧化过程中诱导生成，可调节胆汁酸的生物合成、诱导肿瘤细胞的分化和死亡。

  • GC40065 structure
    GC40065Meloxicam-d3
    CAS: 942047-63-4
    纯度: >99.00%

    An internal standard for the quantification of meloxicam

  • GC40068 structure
    GC40068Setosusin
    CAS: 182926-45-0
    纯度: >99.00%

    A fungal metabolite

  • GC40077 structure
    GC40077Brimonidine-d4
    CAS: 1184971-51-4
    纯度: >99.00%

    An internal standard for the quantification of brimonidine