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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC64290 L-Phenylalanine-d8

    氘代L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid-d8

     L-Phenylalanine-d8 ((S)-2-Amino-3-phenylpropionic acid-d8) 是 L-Phenylalanine 的氘代物。L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) 是分离自大肠杆菌的必需氨基酸。L-Phenylalanine 是一种电压依赖性 α2δ 亚基 Ca2+ 通道拮抗剂，Ki 为 980 nM。L-Phenylalanine 是 NMDARs (KB 573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂。L-Phenylalanine 广泛用于食品香料和药品的生产中。
  3. GC49417 L-Serine-13C3

    L-丝氨酸-13C3,(-)-Serine-13C3; (S)-Serine-13C3

     An internal standard for the quantification of L-serine
  4. GC49461 L-Serine-d7

    L-丝氨酸-D7,(-)-Serine-d7; (S)-Serine-d7

     An internal standard for the quantification of L-serine
  5. GC49370 L-Tryptophan-d5

    L-色氨酸-D5,Tryptophan-d5; Tryptophane-d5

     L-色氨酸-d5（L-Tryptophan-d5）是L-色氨酸的氘代化合物，用作GC或LC-MS定量中的标准品。
  6. GC91889 L-Tyrosine (sodium salt hydrate)

    L-4-Hydroxyphenylalanine; p-Hydroxyphenylalanine; (-)-Tyrosine; p-Tyrosine

     L-Tyrosine (sodium salt hydrate)是一种条件必需氨基酸。
  7. GC48937 L-Tyrosine-13C9,15N

    DL-酪氨酸 13C9,15N

     An internal standard for the quantification of L-tyrosine
  8. GC49371 L-Valine-d8

    L-缬氨酸-D8; L-VALINE-2,3,4,4,4,5,5,5-d8

     An internal standard for the quantification of L-valine
  9. GC47534 Labetalol-d5 (hydrochloride)

    AH 5158A-d5, SCH 15719W-d5

     A neuropeptide with diverse biological activities
  10. GC52497 Lactosylceramide (porcine RBC)

    LacCer

     A sphingolipid
  11. GC40142 Lactosylceramides (bovine buttermilk)

    乳糖苷

     A sphingolipid
  12. GC52331 Lactoyl Phenylalanine

    Lac-Phe, N-Lactoyl-Phenylalanine

     Lactoyl Phenylalanine是一种由乳酸和苯丙氨酸通过胞质非特异性二肽酶（CNDP 2）形成的次级代谢产物。
  13. GC63038 Ladostigil

    TV-3326

     Ladostigil (TV-3326) 是胆碱酯酶 (cholinesterase) 和脑选择性单胺氧化酶 (MAO) 的双重抑制剂，抑制 MAO-B 和 AChE 的 IC50 值分别为 37.1 和 31.8 μM。Ladostigil 能够增加胆碱能的传递，防止 ROS 的形成或其作用，可用于抑郁症和阿尔茨海默氏病的研究。
  14. GC63466 Ladostigil hemitartrate

    乙基甲基-氨基甲酸(3R)-2,3-二氢-3-(2-丙炔氨基)-1H-茚-5-基酯酒石酸盐,TV-3326 hemitartrate

     Ladostigil (TV-3326) hemitartrate 是一种口服有效的胆碱酯酶 (cholinesterase) 和脑选择性单胺氧化酶 (MAO) 的双重抑制剂，抑制 MAO-B 和 AChE 的 IC50 值分别为 37.1 和 31.8 μM。Ladostigil hemitartrate 具有神经保护，抗氧化和抗炎作用，可用于抑郁症和阿尔茨海默症的研究。
  15. GC69353 Ladostigil hydrochloride

    TV-3326 hydrochloride

     Ladostigil (TV-3326) hydrochloride 是一种口服有效的胆碱酯酶 (cholinesterase) 和脑选择性单胺氧化酶 (MAO) 的双重抑制剂，抑制 MAO-B 和 AChE 的 IC50 值分别为 37.1 和 31.8 μM。Ladostigil hydrochloride 具有神经保护，抗氧化和抗炎的作用，可用于抑郁症和阿尔茨海默症的研究。
  16. GC16085 Lafutidine

    拉呋替丁; FRG-8813

     A histamine H2 receptor antagonist with gastroprotective activity
  17. GP10103 Laminin (925-933)

    H2N-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-OH

    层粘连蛋白（925-933）（CDPGYIGSR）是层粘连蛋白 B1 链上的序列。
  18. GC49538 Lamotrigine N2-oxide

    拉莫三嗪N2-氧化物

     A metabolite of lamotrigine
  19. GC52020 Lamotrigine-d3

    拉莫三嗪-[D3]

     An internal standard for the quantification of lamotrigine
  20. GC19217 Lanabecestat

    AZD3293; LY3314814

     An inhibitor of BACE1 and BACE2
  21. GC11124 Lanicemine

    拉尼西明; AZD6765

     A low-trapping NMDA channel blocker
  22. GC61842 Lanicemine dihydrochloride

    拉尼西明二盐酸盐; AZD6765 dihydrochloride; ARL 15896AR

     Lanicemine (AZD6765) dihydrochloride 是一种低捕获的 NMDA 受体拮抗剂，Ki 为 0.56-2.1 µM。CHO 和爪蟾卵母细胞中，IC50 分别为 4-7 µM 和 6.4 µM。具有抗抑郁作用。
  23. GC33822 Larazotide acetate

    醋酸拉瑞唑来

     Larazotide acetate（以前称为 AT-001）是一种高度极性的八肽，来源于霍乱弧菌分泌的原核闭合带蛋白。
  24. GC49608 Larixyl Acetate

    Larixol Acetate

     A diterpenoid with TRPC6 inhibitory and analgesic activities
  25. GC15121 Lasmiditan

    拉米地坦

     An Analytical Reference Standard
  26. GC36428 Lasmiditan hydrochloride An Analytical Reference Standard
  27. GC25563 Lasmiditan succinate

    COL-144, LY573144

     Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
  28. GC47539 Latanoprost (free acid)-d4

    LatFAd4, PhXA 85d4, 17phenyl13,14dihydro trinor Prostaglandin F2αd4

     Internal standard for the quantification of latanoprost (free acid)
  29. GC47540 Latanoprost amide A derivative of latanoprost
  30. GC47541 Latanoprost dimethyl amide A derivative of latanoprost
  31. GC44037 Latanoprost ethyl amide

    LatNEt

     A latanoprost analog
  32. GC47542 Latanoprost ethyl amide-d4

    LatNEtd4

     A neuropeptide with diverse biological activities
  33. GC52264 Latanoprost tris(triethylsilyl) ether

    Latanoprost-related Compound D

     A precursor in the synthesis of latanoprost
  34. GC47543 Latanoprost-d4

    PHXA41-d4

     A neuropeptide with diverse biological activities
  35. GC17974 Latrepirdine dihydrochloride

    2,3,4,5-四氢-2,8-二甲基-5-[2-(6-甲基-3-吡啶基)乙基]-1H-吡啶并[4,3-B]吲哚二盐酸盐,Dimebolin dihydrochloride

     A neuroprotective agent
  36. GC90822 LAU-0901

    一种PAF受体拮抗剂
  37. GC44040 LAU159 A positive allosteric modulator of α6β3γ2 subunit-containing GABAA receptors
  38. GC30979 Lazabemide (Ro 19-6327)

    拉扎贝胺; Ro 19-6327

     An inhibitor of MAO-B
  39. GC17890 LE 300 A dopamine D1-like and 5-HT2A receptor antagonist
  40. GC74450 Lecanemab (Mouse IGG2a) Lecanemab (Mouse IGG2a)是一种针对可溶性β-淀粉样蛋白的单克隆抗体，具有减少认知能力下降的潜力。
  41. GC16931 LED209

    N-苯基-4-(3-苯基硫代脲基)苯磺酰胺

     A potent inhibitor of virulence gene expression
  42. GC47552 Leflunomide-d4

    来氟米特 d4

     An internal standard for the quantification of leflunomide
  43. GC39052 Leptomerine Leptomerine 是一种来自 Esenbeckia leiocarpa Engl. (Rutaceae) 茎中的生物碱。可用于治疗阿尔茨海默氏病。Leptomerine 抑制乙酰胆碱酯酶 (AChE)，IC50 为 2.5 μM。抗胆碱能活性。
  44. GC25569 Lerisetron

    F 0930, F 0930RS

     Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
  45. GC61624 Lesogaberan

    P-[(2R)-3-氨基-2-氟丙基]磷酸,AZD-3355

     Lesogaberan(AZD-3355)是一种有效的选择性GABAB受体激动剂，对人重组GABAB受体的EC50为8.6nM。对大鼠脑GABAB和GABAA受体的结合亲和力(Ki)分别为5.1nM和1.4μM。
  46. GC63041 Lesogaberan hydrochloride

    AZD-3355 hydrochloride

     Lesogaberan (AZD-3355) hydrochloride 是一种有效的选择性 GABAB 受体激动剂，对人重组 GABAB 受体的 EC50 为 8.6 nM。通过脑膜中 [3H]GABA 结合位移测量，Lesogaberan hydrochloride 对大鼠 GABAB 和 GABAA 受体的亲和力 (Kis):分别为 5.1 nM 和 1.4 μM。Lesogaberan hydrochloride 通过外周作用模式抑制短暂的食管下括约肌松弛。
  47. GC33721 Lesopitron dihydrochloride (E4424)

    E4424

     Lesopitron dihydrochloride (E4424) 是一种完全选择性的 5-HT1A 受体激动剂，在大鼠海马膜中的 IC50 为 125 nM。
  48. GC18431 Leteprinim (potassium salt)

    来普利宁钾; AIT-082

     A nootropic and neuroprotective agent
  49. GC49720 Leu-Enkephalin (trifluoroacetate salt)

    Leucine enkephalin, Leu5enkephalin, Tyr-Gly-Gly-Phe-Leu-OH

     A neuropeptide and δ- and ?-opioid receptor agonist
  50. GC45917 Leucettine L41 An inhibitor of DYRK1A, DYRK2, CLK1, and CLK3
  51. GC19221 Leucomethylene blue Mesylate

    TRx0237 mesylate; Methylene blue leuco base mesylate

     An inhibitor of tau aggregation

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