Neuroscience
Neuroscience(神经科学)
Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
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Neuroscience 相关产品(3932)
- GC50031Tandospirone hydrochlorideCAS: 99095-10-0
Tandospirone (SM-3997) hydrochloride 是一种有效的选择性 5-HT1A 受体部分激动剂，Ki 为 27 nM。
- GC50079NS3861 fumarateCAS: 216853-60-0
NS3861 fumarate 是烟碱型乙酰胆碱受体 (nAChRs) 的激动剂，并以高亲和力与异聚体 α3β4 nAChR 结合。
- GC50084Eplivanserin hemifumarateCAS: 130580-02-8纯度: >98.00%
Eplivanserin (SR-46349) hemifumarate 是一种有效、选择性和口服活性的 5-HT2A 受体拮抗剂，在大鼠皮质膜中的 IC50 为 5.8 nM，Kd 为 1.14 nM。
- GC50191Fluoxetine - d5 hydrochlorideCAS: 1173020-43-3纯度: >99.00%
An internal standard for the quantification of fluoxetine
- GC50192Tomoxetine - d3 hydrochlorideCAS: 1217776-38-9
An internal standard for the quantification of atomoxetine
- GC50195Citalopram - d4 hydrobromideCAS: 1219803-58-3纯度: >99.00%
An internal standard for the quantification of citalopram
- GC50202SSR 180711 hydrochlorideCAS: 446031-79-4纯度: >99.50%
SSR 180711 hydrochloride 是一种具有口服活性、选择性和可逆的 α7 乙酰胆碱烟碱受体 (n-AChRs) 部分激动剂。
- GC50213WAY 181187 oxalateCAS: 1883548-85-3
WAY-181187 (SAX-187) oxalate 是一种有效的选择性全 5-HT6 受体激动剂，Ki 为 2.2 nM，EC50 为 6.6 nM。
- GC50305Autocamtide-2-related inhibitory peptide, myristoylatedCAS: 201422-04-0
Autocamtide-2 相关抑制肽，肉豆蔻酰化是肉豆蔻酰化 Autocamtide-2 相关抑制肽。
- GC50306CMPI hydrochloride
Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs
- GC50329M 30 dihydrochlorideCAS: 64821-19-8纯度: >98.50%
M 30 dihydrochloride 是一种具有口服活性、脑渗透性和脑选择性的不可逆 MAO-A (IC50=37 nM) 和 MAO-B (IC50=57 nM) 抑制剂。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC50027 | Xaliproden hydrochloride | 90494-79-4 | >99.00% | |
A 5-HT 1A receptor agonist | ||||
| GC50031 | Tandospirone hydrochloride | 99095-10-0 | - | |
Tandospirone (SM-3997) hydrochloride 是一种有效的选择性 5-HT1A 受体部分激动剂，Ki 为 27 nM。 | ||||
| GC50033 | RS 127445 hydrochloride | 199864-86-3 | >99.50% | |
A 5-HT 2B receptor antagonist | ||||
| GC50042 | CP 122721 hydrochloride | 145877-52-7 | - | |
High affinity NK1 antagonist | ||||
| GC50069 | GR 203040 | 168398-02-5 | - | |
Potent and selective NK1 antagonist | ||||
| GC50079 | NS3861 fumarate | 216853-60-0 | - | |
NS3861 fumarate 是烟碱型乙酰胆碱受体 (nAChRs) 的激动剂，并以高亲和力与异聚体 α3β4 nAChR 结合。 | ||||
| GC50084 | Eplivanserin hemifumarate | 130580-02-8 | >98.00% | |
Eplivanserin (SR-46349) hemifumarate 是一种有效、选择性和口服活性的 5-HT2A 受体拮抗剂，在大鼠皮质膜中的 IC50 为 5.8 nM，Kd 为 1.14 nM。 | ||||
| GC50088 | A 85380 dihydrochloride | 174740-86-4 | - | |
High affinity and selective α4β2 nAChR agonist | ||||
| GC50126 | CC4 | 492-02-4 | - | |
High affinity and subtype-selective α6β2 and α4β2 nAChR partial agonist | ||||
| GC50191 | Fluoxetine - d5 hydrochloride | 1173020-43-3 | >99.00% | |
An internal standard for the quantification of fluoxetine | ||||
| GC50192 | Tomoxetine - d3 hydrochloride | 1217776-38-9 | - | |
An internal standard for the quantification of atomoxetine | ||||
| GC50193 | Clozapine - d8 | 1185053-50-2 | - | |
Clozapine - d8 (HF 1854-d8) 是氘标记的氯氮平。 | ||||
| GC50195 | Citalopram - d4 hydrobromide | 1219803-58-3 | >99.00% | |
An internal standard for the quantification of citalopram | ||||
| GC50198 | Topiramate - d12 | 1279037-95-4 | - | |
An internal standard for the quantification of topiramate | ||||
| GC50199 | Ropinirole - d7 | 1261396-31-9 | - | |
An internal standard for the quantification of ropinirole | ||||
| GC50202 | SSR 180711 hydrochloride | 446031-79-4 | >99.50% | |
SSR 180711 hydrochloride 是一种具有口服活性、选择性和可逆的 α7 乙酰胆碱烟碱受体 (n-AChRs) 部分激动剂。 | ||||
| GC50213 | WAY 181187 oxalate | 1883548-85-3 | - | |
WAY-181187 (SAX-187) oxalate 是一种有效的选择性全 5-HT6 受体激动剂，Ki 为 2.2 nM，EC50 为 6.6 nM。 | ||||
| GC50258 | (R)-Citalopram oxalate | 219861-53-7 | - | |
Enantiomer of escitalopram oxalate | ||||
| GC50260 | HS 38 | 1030203-81-6 | >99.00% | |
HS 38 是一种有效的、选择性的和 ATP 竞争性的死亡相关蛋白激酶 1 (DAPK1) 和拉链相互作用蛋白激酶 (ZIPK，也称为 DAPK3) 抑制剂，Kd 值分别为 300 nM 和 280 nM。 | ||||
| GC50305 | Autocamtide-2-related inhibitory peptide, myristoylated | 201422-04-0 | - | |
Autocamtide-2 相关抑制肽，肉豆蔻酰化是肉豆蔻酰化 Autocamtide-2 相关抑制肽。 | ||||
| GC50306 | CMPI hydrochloride | - | - | |
Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs | ||||
| GC50320 | Calcitonin (human) | 21215-62-3 | - | |
A peptide hormone that lowers blood calcium levels | ||||
| GC50329 | M 30 dihydrochloride | 64821-19-8 | >98.50% | |
M 30 dihydrochloride 是一种具有口服活性、脑渗透性和脑选择性的不可逆 MAO-A (IC50=37 nM) 和 MAO-B (IC50=57 nM) 抑制剂。 | ||||
| GC50355 | NS 6740 | 753499-14-8 | - | |
High affinity α7 nAChR partial agonist; anti-inflammatory | ||||