SSR 180711 hydrochloride

目录号: GC50202纯度: >99.50%
SSR 180711 hydrochloride 是一种具有口服活性、选择性和可逆的 α7 乙酰胆碱烟碱受体 (n-AChRs) 部分激动剂。

SSR 180711 hydrochloride
Cas No.: 446031-79-4
规格价格库存数量操作
5mg¥675.00现货
1
10mg¥1,125.00现货
1
25mg¥2,250.00现货
1
50mg¥3,600.00现货
1
100mg¥5,400.00现货
1
10mM (in 1mL DMSO)¥747.00现货
1

文献被引

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产品描述 Description

Partial agonist at α7 nAChR. Enhances episodic memory and reverses MK-801-induced deficits in retention of episodic memory. Increases extracellular dopamine levels in rat prefrontal cortex. Also exhibits antidepressant-like properties.

Jones et al (2014) Effect of α7 nicotinic acetylcholine receptor agonists on attentional set-shifting impairment in rats. Psychopharmacology (Berl). 231 673 PMID:24057763 |Pichat et al (2007) SSR180711, a novel selective α7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia. Neuropsychopharmacology 32 17 PMID:16936709

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
446031-79-4
SMILES
O=C(N1C2CCN(CC2)CC1)OC3=CC=C(Br)C=C3.Cl
分子式
C14H17BrN2O2.HCl
分子量
361.66 g/mol
溶解性
Soluble in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol