Cell Cycle/Checkpoint
Cell Cycle/Checkpoint(细胞周期/检查点)
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more
- ATM/ATR(29)
- Aurora Kinase(58)
- Cdc42(4)
- Cdc7(3)
- Chk(14)
- c-Myc(27)
- CRM1(8)
- Cyclin-Dependent Kinases(77)
- E1 enzyme(1)
- G-quadruplex(12)
- Haspin(6)
- HMTase(1)
- Kinesin(27)
- Ksp(4)
- Microtubule/Tubulin(257)
- Mps1(15)
- Mitotic(7)
- RAD51(13)
- ROCK(74)
- Rho(13)
- PERK(11)
- PLK(43)
- PTEN(6)
- Wee1(9)
- PAK(25)
- Arp2/3 Complex(8)
- Dynamin(14)
- ECM & Adhesion Molecules(54)
- Cytoskeleton & Motor Proteins(65)
- Endomembrane System & Vesicular Trafficking(36)
- G1(51)
- Genotoxic Stress(23)
- G2/M(40)
- G2/S(17)
- Inositol Phosphates(67)
- Proteolysis(183)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(1)
- MARK(3)
- NEKs(1)
Cell Cycle/Checkpoint 相关产品(1379)
- GC50020Dynamin inhibitory peptide, myristoylatedCAS: 251634-22-7
DynaMin inhibitory peptide, myristoylated 是一种 DynaMin 抑制剂，可干扰两性霉素与 dynamin 的结合。
- GC50214LCB 03-0110 dihydrochlorideCAS: 1962928-28-4
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk
- GC50314PF 3758309 dihydrochloride
PF 3758309 dihydrochloride是 ATP竞争性p21活化激酶4（PAK4）抑制剂，其Kd值为2.7nM，Ki值为18.7nM。
- GC50370AZ 13705339CAS: 2016806-57-6
AZ 13705339 是一种高效的选择性 PAK1 抑制剂，对 PAK1 和 pPAK1 的 IC50 分别为 0.33 nM 和 59 nM。 AZ 13705339 与 PAK1 和 PAK2 具有结合亲和力，Kds 分别为 0.28 nM 和 0.32 nM。 AZ 13705339 可用于癌症研究。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC49915 | Hexa-D-Arginine (trifluoroacetate salt) | - | >95.00% | |
A furin inhibitor | ||||
| GC50020 | Dynamin inhibitory peptide, myristoylated | 251634-22-7 | - | |
DynaMin inhibitory peptide, myristoylated 是一种 DynaMin 抑制剂，可干扰两性霉素与 dynamin 的结合。 | ||||
| GC50043 | SR 3677 dihydrochloride | 1781628-88-3 | - | |
A ROCK1 and ROCK2 inhibitor | ||||
| GC50045 | PD 166285 dihydrochloride | 212391-63-4 | - | |
A tyrosine kinase inhibitor | ||||
| GC50050 | Hesperadin hydrochloride | - | - | |
A multi-kinase inhibitor | ||||
| GC50052 | Laulimalide | 115268-43-4 | - | |
Microtubule stabilzing agent | ||||
| GC50056 | UA 62784 | 313367-92-9 | - | |
Inhibits microtubule polymerization | ||||
| GC50092 | RKI 1447 dihydrochloride | 1782109-09-4 | >98.00% | |
A ROCK1 and ROCK2 inhibitor | ||||
| GC50110 | Mps1-IN-1 dihydrochloride | 1883548-93-3 | - | |
A selective Mps1 kinase inhibitor | ||||
| GC50116 | OXA 06 dihydrochloride | 1825455-91-1 | - | |
Potent ROCK inhibitor | ||||
| GC50145 | CHR 6494 trifluoroacetate | 1458630-17-5 | - | |
A selective Haspin protein kinase inhibitor | ||||
| GC50175 | CGP 74514 dihydrochloride | - | - | |
Potent cdk1 inhibitor | ||||
| GC50214 | LCB 03-0110 dihydrochloride | 1962928-28-4 | - | |
Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk | ||||
| GC50314 | PF 3758309 dihydrochloride | - | - | |
PF 3758309 dihydrochloride是 ATP竞争性p21活化激酶4（PAK4）抑制剂，其Kd值为2.7nM，Ki值为18.7nM。 | ||||
| GC50370 | AZ 13705339 | 2016806-57-6 | - | |
AZ 13705339 是一种高效的选择性 PAK1 抑制剂，对 PAK1 和 pPAK1 的 IC50 分别为 0.33 nM 和 59 nM。 AZ 13705339 与 PAK1 和 PAK2 具有结合亲和力，Kds 分别为 0.28 nM 和 0.32 nM。 AZ 13705339 可用于癌症研究。 | ||||
| GC50397 | Flutax 2 | 301844-13-3 | >93.00% | |
绿色荧光紫杉醇衍生物；结合微管 | ||||
| GC50424 | AZ 5704 | 1941214-06-7 | - | |
Potent and selective ATM kinase inhibitor; orally bioavailable | ||||
| GC50439 | Peptide5 | 916977-43-0 | - | |
Peptide5 是一种连接蛋白 43 模拟肽，可减少脊髓损伤后动物肿胀、星形胶质细胞增生和神经元细胞死亡体外:Peptide5 显着降低啮齿动物离体模型中的脊髓损伤 (SCI) 程度。 | ||||
| GC50529 | Surfen | 5424-37-3 | - | |
Surfen 是一种有效的 HS（硫酸乙酰肝素）拮抗剂。 | ||||
| GC50574 | MB 0223 | 2247732-89-2 | - | |
Dynamin-related GTPase DRP1 partial inhibitor | ||||
| GC50599 | P110 | 1411976-18-5 | - | |
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52029 | 2-Aminoflubendazole | 82050-13-3 | >95.00% | |
A metabolite of flubendazole | ||||
| GC52054 | Ranitidine S-oxide | 73851-70-4 | >90.00% | |
A metabolite of ranitidine | ||||