Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC44667 Ponasterone A

坡那甾酮A,25-Deoxyecdysterone
An ecdysteroid hormone
GC36947 Porcine dynorphin A(1-13)

强啡肽A(1-13),Dynorphin A Porcine Fragment 1-13
Porcine dynorphin A (1-13) 是一个有效的内源性阿片受体 (κ opioid receptor) 激动剂，在生理浓度下它有镇痛作用。
GC44674 Pramlintide (acetate hydrate)

醋酸普兰林肽
An amylin analog
GC47969 Precocene II

早熟素Ⅱ
A chromene with anti-juvenile hormone activity
GC44677 Prednicarbate

泼尼卡酯
A synthetic corticosteroid
GC44679 Prednisone 21-aldehyde/22-hydroxy Prednisone A mixture of a derivative and an adduct of prednisone
GC47970 Prednisone-d7

1,2-Dehydrocortisone-d7
A neuropeptide with diverse biological activities
GC41266 Pregnanediol-3-Glucuronide

Pregnanediol-3α-Glucuronide
A metabolite of progesterone
GC48724 Pregnanetriol

孕三醇
A metabolite of 17α-hydroxyprogesterone
GC47973 PRGL493 An ACSL4 inhibitor
GC44686 Prochloraz

咪鲜胺; BTS 40542

An imidazole antifungal
GC12408 Progesterone

孕酮; Pregn-4-ene-3,20-dione
An endogenous hormone and hormone precursor
GC44691 Progesterone 3-biotin An affinity probe
GC44692 Progesterone 3-PEG11-biotin A hydrophilic affinity probe
GC44693 Progesterone-3-biotinyl Photoaffinity Probe

P4, P4 Binding Probe
A photoaffinity probe
GC47976 Progesterone-d9

氘代黄体酮/氘代4-烯-3,20-二酮,Pregn-4-ene-3,20-dione-d9
An internal standard for the quantification of progesterone
GC47979 Propiconazole-d7 An internal standard for the quantification of propiconazole
GC14370 Propyl pyrazole triol (PPT)

PPT
Propyl pyrazole triol (PPT)是一种选择性雌激素受体α（ERα）激动剂，可通过在神经系统激活ERα，保护神经元免受氧化应激与炎症损伤。
GC47982 Propylthiouracil-d5

6-n-Propylthiouracil-d5; 6-Propyl-2-thiouracil-d5; PTU-d5
An internal standard for the quantification of propylthiouracil
GC36981 PROTAC AR Degrader-4 PROTAC AR Degrader-4 包含 cIAP1 配体结合基团，linker 和雄激素受体 (AR) 配体结合基团。基于 cIAP1 的降解剂也被称为 SNIPER。
GC61481 PROTAC AR Degrader-4 TFA PROTACARDegrader-4包含cIAP1配体结合基团，linker和雄激素受体(AR)配体结合基团。基于cIAP1的降解剂也被称为SNIPER。
GC34740 PROTAC RAR Degrader-1 PROTACRARDegrader-1包含cIAP1配体结合基团，linker和RAR配体结合基团。在HT1080细胞中，PROTACRARDegrader-1降低RAR水平，30μM浓度时达到最大降解程度。同时，基于cIAP1的降解剂也被称为SNIPER。
GC30588 Protirelin (Synthetic thyrotropin-releasing factor)

普罗瑞林; Thyrotropin-releasing-hormone; TRH

A tropic hormone
GC33845 Protirelin Acetate (TRF Acetate)

醋酸普罗瑞林; Thyrotropin-releasing-hormone acetate; TRH acetate
Protirelin (Thyroliberin, Lopremone, Synthetic TRH, Thyrotropin-releasing hormone, Rifathyroin) is a tripeptide that stimulates the release of thyrotropin and prolactin.
GC33224 Proxalutamide (GT0918)

GT0918; Pruxelutamide
Proxalutamide (GT0918) is a second-generation androgen receptor antagonist that binds to the ligand-binding domain of AR with an IC50 of 32 nM in the AR competive binding assays.
GA23395 pTH (1-34) (rat)

甲状旁腺素(鼠)
pTH (1-34)（大鼠）是一种甲状旁腺激素。
GC74383 pTH (44-68) (human) TFA pTH (44-68) (human) TFA是人类甲状旁腺激素pTH的片段，缺乏完整pTH的腺苷酸环化酶刺激活性。
GC31395 PX20606 trans racemate (PX-102 trans racemate)

CPDD1220反式消旋体,PX-102 trans racemate
PX20606 trans racemate (PX-102 trans racemate) (PX-102 trans racemate) 是一种 FXR 激动剂，在 FRET 和 M1H 试验中对 FXR 的 EC50 分别为 32 和 34 nM。
GC30771 PZM21 A μ-opioid receptor agonist
GC12644 Quinestrol

炔雌醇环戊醚,Estrovis?,Ethynyl Estradiol-3-cyclopentyl ether,W 3566

A synthetic estrogen
GC49108 Racecadotril-d5

消旋卡多曲杂质,Acetorphan-d5
An internal standard for the quantification of racecadotril
GC19305 RAD140

RAD140
An androgen receptor modulator
GC91430 RAD150 RAD150是一种非类固醇雄激素受体调节剂（IC50 = 130 nM），是选择性雄激素受体调节剂（SARM）RAD140的苯甲酸酯衍生物。
GC62683 Ralaniten

EPI-002
Ralaniten (EPI-002) 是一种有效和具有口服活性的雄激素受体 N 端结构域 (AR-NTD) 拮抗剂。Ralaniten 抑制 AR 转录活性，IC50 值为 7.4 μM。Ralanites 可用于去势抵抗性前列腺癌 (CRPC) 的研究。
GC62603 Ralaniten triacetate

EPI-506
Ralaniten triacetate (EPI-506) 是 Ralaniten 的前药，是一种首创的，具有口服活性的雄激素受体 (AR) N 端结构域 (NTD) 抑制剂。Ralaniten triacetate 对全长和与抗性相关的 AR 物种，包括 AR-v7 都有活性。
GC25832 Raloxifene

Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129
Raloxifene (Keoxifene, Pharoxifene, LY-139481, LY-156758, CCRIS-7129) is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.
GC13350 Raloxifene HCl

盐酸雷洛昔芬; Keoxifene hydrochloride; LY156758; LY139481 hydrochloride
A selective estrogen receptor modulator
GC48023 Raloxifene-d4 (hydrochloride)

雷洛昔芬-D4,盐酸盐
An internal standard for the quantification of raloxifene
GC49653 Ramipril Diketopiperazine

雷米普利二酮哌嗪
A potential impurity found in commercial preparations of ramipril
GC49408 Ramipril Diketopiperazine Acid

雷米普利杂质K
A potential impurity found in commercial preparations of ramipril
GC11957 RD162

N-甲基-4-[7-(4-氰基-3-三氟甲基苯基)-8-氧代-6-硫酮-5,7-二氮杂螺[3.4]辛烷-5-基]-2-氟苯甲酰胺
A second-generation androgen receptor antagonist
GC32934 Relugolix (TAK-385)

瑞卢戈利; TAK-385
A GnRH receptor antagonist
GC44812 Renin Fluorogenic Substrate A probe for renin activity
GC31345 Retinol (Vitamin A1)

视黄醇
视黄醇,也称为维生素A 1 ,是维生素A家族中的一种脂溶性维生素,存在于食物中,用作膳食补充剂。
GC63402 Rezvilutamide

SHR3680
Rezvilutamide (SHR3680) 雄激素受体 (androgen receptor) 的拮抗剂。Rezvilutamide (SHR3680) 可用于前列腺癌的研究。
GC19448 RGX-104

Abequolixron hydrochloride
RGX-104 是一种小分子 LXR 激动剂，通过 ApoE 基因的转录激活来调节先天免疫。
GC37525 RGX-104 free Acid

Abequolixron
RGX-104 free Acid 是具有口服生物活性的、有效的肝X核激素受体 (LXRβ) 激动剂，通过ApoE基因的转录激活调节先天免疫。
GC66433 Ro 41-5253 Ro 41-5253 是一种具有口服活性的选择性维甲酸受体 RARα 拮抗剂。Ro 41-5253 可以与 RARα 结合而不诱导转录或影响 RAR/RXR 异二聚化和 DNA 结合。Ro 415253 可抑制癌细胞增殖并诱导细胞凋亡 (apoptosis)，具有抗肿瘤活性。
GC38842 Ro 64-6198 Ro 64-6198 是一种有效的，选择性的，非肽，高亲和力，高细胞通透性和脑渗透 N/OFQ 受体 (NOP) 激动剂，EC50 值为 25.6 nM。Ro 64-6198 对 NOP 受体的选择性至少是经典阿片受体的 100 倍。Ro 64-6198 可用于治疗压力和焦虑，成瘾，神经性疼痛，咳嗽和厌食症。
GC15736 Rosuvastatin Calcium

瑞舒伐他汀钙; Rosuvastatin hemicalcium; ZD 4522 Calcium
An HMG-CoA reductase inhibitor