Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC17983 Taltirelin
他替瑞林; TA-0910
Taltirelin (TA0910) 是促甲状腺素释放激素受体 (TRH-R) 的超级激动剂，IC50 为 910 nM，EC50 为 36 nM，可刺激细胞溶质 Ca2+ 浓度（Ca2+ 释放）的增加。
GC11781 Medroxyprogesterone
甲羟孕酮; 17α-Hydroxy-6α-methylprogesterone; U8840
A progesterone receptor agonist
GC13303 Etonogestrel
依托孕烯,3-Oxodesogestrel; 3-keto-Desogestrel
A steroidal progestin
GC15366 Clomiphene citrate
枸橼酸氯米芬; Clomifene citrate
A selective estrogen receptor modulator
GC12974 Medroxyprogesterone acetate
醋酸甲羟孕酮; Medroxyprogesterone 17-acetate; Farlutin
Medroxyprogesterone acetate（MPA）是一种人工合成的孕激素。
GC10702 Trimebutine
曲美布汀
An opioid receptor agonist
GC11436 Ethisterone
炔孕酮,Pregneninolone; 17α-Ethynyltestosterone
A synthetic progestin
GC12815 Formestane
福美司坦
An Analytical Reference Standard
GC11885 Sevelamer HCl
盐酸司维拉姆
Sevelamer HCl 是一种磷酸盐结合药物，用于治疗慢性肾病患者的高磷血症；由与环氧氯丙烷交联的聚烯丙胺组成。
GC14273 TTNPB (Arotinoid Acid)
Ro 13-7410; Arotinoid acid; AGN191183
A potent, selective RAR agonist
GC15001 Tiratricol
替拉曲可,3,3',5-Triiodothyroacetic acid
A thyroid hormone receptor agonist
GC12516 Spironolactone
螺内酯; SC9420
Spironolactone是一种具有口服活性的盐皮质激素受体（MR；IC₅₀=24nM）和雄激素受体（AR；IC₅₀=77nM）双重拮抗剂。
GC11822 Erteberel (LY500307)
芬克罗酮,LY500307
A potent and selective agonist of ERβ
GC12409 Liothyronine Sodium
三碘代甲状腺素钠盐
Liothyronine sodium 是一种强效的甲状腺激素受体TRα和TRβ激动剂，其 Ki 值为 2.33nM。
GC15324 Hexestrol
4,4'-(1,2-二乙基亚乙基)二苯酚
A synthetic non-steroidal estrogen receptor ligand
GC12126 Flutamide
氟他胺; SCH 13521
An androgen receptor antagonist and a prodrug form of 2-hydroxy flutamide
GC12000 Ethynodiol diacetate
双醋炔诺醇,Ethynodiol acetate
A synthetic progestogen
GC12182 Estriol
雌三醇; Oestriol
Estriol是雌激素受体（ERα和ERβ）的激动剂和G蛋白偶联受体30（GPR30）的拮抗剂。
GC11796 Estradiol valerate
戊酸雌二醇,β-Estradiol 17-valerate
A synthetic estrogen
GC10139 Estradiol Cypionate
环戊丙酸雌二醇
A synthetic estrogen
GC16292 Equol
(±)-雌马酚
An estrogen receptor agonist
GC13072 Epiandrosterone
表雄酮; 3β-Androsterone; trans-Androsterone; iso-Androsterone
An Analytical Reference Standard
GC10245 Bazedoxifene HCl
盐酸巴多昔芬,TSE-424 hydrochloride
Bazedoxifene HCl (TSE-424 hydrochloride) 是一种具有口服活性、可渗透 BBB 的非甾体选择性雌激素受体调节剂 (SERM)，对 ERα 的 IC50 分别为 23 nM 和 99 nM；和ERβ，分别。盐酸巴多昔芬可用于骨质疏松症的研究。 Bazedoxifene HCl 作为 IL-6/GP130 蛋白质-蛋白质相互作用的抑制剂。 Bazedoxifene HCl 可用于胰腺癌的研究。
GC12434 AZD1981 A DP₂/CRTH₂ receptor antagonist
GC13297 Altrenogest
四烯雌酮,Allyltrenbolone; RU2267
A synthetic progestin
GC14704 Levonorgestrel
左炔诺孕酮; D-Norgestrel
Levonorgestrel是一种口服有效的孕酮抑制剂。
GC16433 Aminoglutethimide
氨鲁米特,DL-Aminoglutethimide
An aromatase inhibitor
GC12379 Drospirenone
屈螺酮,Dihydrospirorenone
A synthetic progestogen
GC10017 Gestodene
孕二烯酮; SHB 331; WL 70
A progestin
GC17113 Acitretin sodium
阿维A钠; Ro 10-1670 sodium
A retinoid
GC14379 Adapalene sodium salt
阿达帕林钠; CD 271 sodium salt
An RARβ and RARγ agonist
GC15578 Dienogest
地诺孕素; STS 557
A synthetic progestin and PR agonist
GC13835 Toremifene Citrate
枸橼酸托瑞米芬; Z-Toremifene citrate; NK 622; FC-1157a
A selective estrogen receptor modulator
GC17985 Chenodeoxycholic Acid
鹅去氧胆酸
A primary bile acid
GC10760 XL335
3-(3,4-二氟苯甲酰基)-1,2,3,6-四氢-1,1-二甲基氮杂卓[4,5-B]吲哚-5-甲酸1-甲基乙基酯,FXR-450; XL335; WAY-362450
A potent and selective FXR agonist
GC10975 GW4064
3-(2,6-二氯苯基)-4-(3'-羧基-2-氯二苯乙烯-4-基)氧甲基-5-异丙基异恶唑
GW4064作为合成的FXR激动剂，用于治疗胆汁淤积性肝病、代谢综合征和酒精性肝病。
GC11268 L-Thyroxine
L-甲状腺素,Levothyroxine; T4
L-Thyroxine是一种合成甲状腺激素，可模拟甲状腺分泌的天然甲状腺素，对调节新陈代谢、促进生长发育等起着关键作用。L-Thyroxine常用于治疗甲状腺功能减退症及其他甲状腺相关疾病。
GC11016 Meptazinol HCl
盐酸美普他酚
μ1 阿片受体的部分激动剂
GC11677 Ulipristal acetate
醋酸乌利司他; CDB-2914
A selective progesterone receptor modulator
GC14304 Palovarotene
4-[(1E)-2-[5,6,7,8-四氢-5,5,8,8-四甲基-3-(1H-吡唑-1-基甲基)-2-萘基]乙烯基]苯甲酸,R 667; Ro 3300074
A RARγ agonist
GC11070 Dehydroepiandrosterone (DHEA)
脱氢表雄酮; Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone

脱氢表雄酮 (DHEA) 及其硫酸酯 DHEAS 共同代表了人体内最丰富的类固醇激素。
GC10256 Anastrozole
阿那曲唑; ZD1033
An aromatase/CYP19A1 inhibitor
GC11669 Tamoxifen Citrate
他莫昔芬柠檬酸盐; ICI 46474; (Z)-Tamoxifen Citrate; trans-Tamoxifen Citrate
A selective estrogen receptor modulator
GC13350 Raloxifene HCl
盐酸雷洛昔芬; Keoxifene hydrochloride; LY156758; LY139481 hydrochloride
A selective estrogen receptor modulator
GC11688 Megestrol Acetate
醋酸甲地孕酮
A synthetic progestogen
GC17572 Finasteride acetate
醋酸非那雄胺; MK-906 acetate
An inhibitor of 5α-reductase type II
GC13954 LXR-623
2-[(2-氯-4-氟苯基)甲基]-3-(4-氟苯基)-7-(三氟甲基)-2H-吲唑,WAY 252623
An LXR modulator
GC10789 XCT790
3-[4-[[2,4-二(三氟甲基)苄基]氧基]-3-甲氧基苯基]-2-氰基-N-(5-三氟甲基-[1,3,4]噻二唑-2-基)丙烯酰胺
XCT790是一种高效、选择性的ERRα反向激动剂，IC₅₀为0.37μM。
GC13362 TOK-001
TOK-001; VN-124-1
A CYP17 inhibitor
GC13971 Cyproterone Acetate
醋酸环丙孕酮
An androgen receptor antagonist