Ubiquitination/ Proteasome
Ubiquitination/ Proteasome(泛素化/蛋白酶体)
Ubiquitination/ Proteasome 相关产品(1292)
- GC19729Adenosine 5′-diphosphoribose sodiumCAS: 68414-18-6纯度: >99.00%
Adenosine 5′-diphosphoribose sodium是一种核苷酸衍生物,是Transient receptor potential melastatin 2 (TRPM2)激动剂,在细胞内多种代谢途径中发挥着重要作用。
- GC19766Heparin sodium salt (MW 15kDa)CAS: 9041-08-1纯度: >99.50%
肝素钠盐(MW 15kDa)(Sodium heparin (MW 15kDa))是肝素的聚合物,分子量为15kDa。
- GC250195-amino-2,4-dimethylpyridine (5A-DMP)CAS: 1193-71-1
5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts
- GC25650MRT67307 HClCAS: 1781882-89-0
MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy.
- GC25651MRT68921 HClCAS: 2070014-87-6
MRT68921 HCl是一种强效的ULK1和ULK2双重抑制剂,对ULK1和ULK2的IC 50 值分别为2.9nM和1.1nM。
- GC3001120-DeoxyingenolCAS: 54706-99-9纯度: >98.00%
A diterpenoid with antioxidant and osteoprotective activities
- GC30054Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate)CAS: 24868-20-0纯度: >98.00%
Dantrolene sodium hemiheptahydrate (Dantrium) ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.
- GC30056Danthron (Dantron)CAS: 117-10-2纯度: >98.50%
Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.
- GC30072Dansylcadaverine (Monodansyl cadaverine)CAS: 10121-91-2纯度: >98.00% / >97.00%
A fluorescent marker for autophagic vacuoles
- GC30158p38-α MAPK-IN-1CAS: 443913-15-3纯度: >99.50%
p38-α MAPK-IN-1 is an inhibitor of p38-α, with IC50 value of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.
- GC30263Glucosamine (D-Glucosamine)CAS: 3416-24-8纯度: >98.00%
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine(GS) treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.
- GC30343Selenomethionine (Seleno-DL-methionine)CAS: 1464-42-2纯度: >98.00%
硒代蛋氨酸(Seleno-DL-methionine)是一种天然存在的含硒氨基酸,是硒的常见天然食物来源。
- GC30646Skatole(3-Methylindole)CAS: 83-34-1纯度: >99.50%
Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.
- GC30744Norepinephrine (Adrenor)CAS: 51-41-2纯度: >98.00%
(-)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.
- GC30761α-Hydroxylinoleic acidCAS: 57818-44-7纯度: >98.00%
ABTL0812 (α-Hydroxylinoleic acid, LP-10218, SCLN-0812) inhibits Akt/mTOR axis by inducing the overexpression of TRIB3 and activating autophagy in lung squamous carcinoma cell lines. ABTL0812 also induces AMPK activation and ROS accumulation.
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC19729 | Adenosine 5′-diphosphoribose sodium | 68414-18-6 | >99.00% | |
Adenosine 5′-diphosphoribose sodium是一种核苷酸衍生物,是Transient receptor potential melastatin 2 (TRPM2)激动剂,在细胞内多种代谢途径中发挥着重要作用。 | ||||
| GC19766 | Heparin sodium salt (MW 15kDa) | 9041-08-1 | >99.50% | |
肝素钠盐(MW 15kDa)(Sodium heparin (MW 15kDa))是肝素的聚合物,分子量为15kDa。 | ||||
| GC25019 | 5-amino-2,4-dimethylpyridine (5A-DMP) | 1193-71-1 | - | |
5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts | ||||
| GC25650 | MRT67307 HCl | 1781882-89-0 | - | |
MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy. | ||||
| GC25651 | MRT68921 HCl | 2070014-87-6 | - | |
MRT68921 HCl是一种强效的ULK1和ULK2双重抑制剂,对ULK1和ULK2的IC 50 值分别为2.9nM和1.1nM。 | ||||
| GC30011 | 20-Deoxyingenol | 54706-99-9 | >98.00% | |
A diterpenoid with antioxidant and osteoprotective activities | ||||
| GC30054 | Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate) | 24868-20-0 | >98.00% | |
Dantrolene sodium hemiheptahydrate (Dantrium) ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. | ||||
| GC30056 | Danthron (Dantron) | 117-10-2 | >98.50% | |
Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes. | ||||
| GC30072 | Dansylcadaverine (Monodansyl cadaverine) | 10121-91-2 | >98.00% / >97.00% | |
A fluorescent marker for autophagic vacuoles | ||||
| GC30158 | p38-α MAPK-IN-1 | 443913-15-3 | >99.50% | |
p38-α MAPK-IN-1 is an inhibitor of p38-α, with IC50 value of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. | ||||
| GC30263 | Glucosamine (D-Glucosamine) | 3416-24-8 | >98.00% | |
Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine(GS) treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites. | ||||
| GC30343 | Selenomethionine (Seleno-DL-methionine) | 1464-42-2 | >98.00% | |
硒代蛋氨酸(Seleno-DL-methionine)是一种天然存在的含硒氨基酸,是硒的常见天然食物来源。 | ||||
| GC30356 | Metofenazate (Methophenazine) | 388-51-2 | - | |
Metofenazate (Methophenazine) 是一种选择性钙调蛋白抑制剂。 | ||||
| GC30360 | Cresol (Cresol mixture of isomers) | 1319-77-3 | - | |
Cresol是一种有机化合物,是芳香族有机化合物广泛存在的天然及合成基团。 | ||||
| GC30366 | FAAH-IN-2 | 184475-71-6 | >99.40% | |
FAAH-IN-2是摘自专利WO/2008/100977A2中的FAAH抑制剂。 | ||||
| GC30537 | BPO-27 racemate | 1314873-02-3 | >98.00% | |
BPO-27racemate是有效的CFTR抑制剂,IC50值为8nM。 | ||||
| GC30565 | BAR502 | 1612191-86-2 | >98.00% | |
A dual agonist of GP-BAR1 and FXR | ||||
| GC30608 | Ipsalazide | 82101-17-5 | - | |
Ipsalazide是一种新的柳氮磺吡啶类似物,旨在释放胃肠道中的5-氨基水杨酸和无毒载体分子。 | ||||
| GC30609 | p38 MAPK-IN-2 | 635725-16-5 | - | |
p38MAPK-IN-2是一种p38kinase的抑制剂。 | ||||
| GC30646 | Skatole(3-Methylindole) | 83-34-1 | >99.50% | |
Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect. | ||||
| GC30676 | MAPK13-IN-1 | 229002-10-2 | >98.00% | |
MPAK13-IN-1是MAPK13(p38δ)的一个抑制剂,其IC50值为620nM。 | ||||
| GC30744 | Norepinephrine (Adrenor) | 51-41-2 | >98.00% | |
(-)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively. | ||||
| GC30751 | FAAH-IN-1 | 1242441-47-9 | - | |
FAAH-IN-1是脂肪酸酰胺水解酶(FAAH)抑制剂,对大鼠和人FAAH的IC50值分别为145nM和650nM。 | ||||
| GC30761 | α-Hydroxylinoleic acid | 57818-44-7 | >98.00% | |
ABTL0812 (α-Hydroxylinoleic acid, LP-10218, SCLN-0812) inhibits Akt/mTOR axis by inducing the overexpression of TRIB3 and activating autophagy in lung squamous carcinoma cell lines. ABTL0812 also induces AMPK activation and ROS accumulation. | ||||
