Ubiquitination/ Proteasome

Ubiquitination/ Proteasome(泛素化/蛋白酶体)

研究方向

Ubiquitination/ Proteasome 相关产品(1292)

  • GC19729 structure
    GC19729Adenosine 5′-diphosphoribose sodium
    CAS: 68414-18-6
    纯度: >99.00%

    Adenosine 5′-diphosphoribose sodium是一种核苷酸衍生物,是Transient receptor potential melastatin 2 (TRPM2)激动剂,在细胞内多种代谢途径中发挥着重要作用。

  • GC19766 structure
    GC19766Heparin sodium salt (MW 15kDa)
    CAS: 9041-08-1
    纯度: >99.50%

    肝素钠盐(MW 15kDa)(Sodium heparin (MW 15kDa))是肝素的聚合物,分子量为15kDa。

  • GC25019 structure
    GC250195-amino-2,4-dimethylpyridine (5A-DMP)
    CAS: 1193-71-1

    5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts

  • GC25650 structure
    GC25650MRT67307 HCl
    CAS: 1781882-89-0

    MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy.

  • GC25651 structure
    GC25651MRT68921 HCl
    CAS: 2070014-87-6

    MRT68921 HCl是一种强效的ULK1和ULK2双重抑制剂,对ULK1和ULK2的IC 50 值分别为2.9nM和1.1nM。

  • GC30011 structure
    GC3001120-Deoxyingenol
    CAS: 54706-99-9
    纯度: >98.00%

    A diterpenoid with antioxidant and osteoprotective activities

  • GC30054 structure
    GC30054Dantrolene sodium hemiheptahydrate (Dantrolene sodium hydrate)
    CAS: 24868-20-0
    纯度: >98.00%

    Dantrolene sodium hemiheptahydrate (Dantrium) ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.

  • GC30056 structure
    GC30056Danthron (Dantron)
    CAS: 117-10-2
    纯度: >98.50%

    Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.

  • GC30072 structure
    GC30072Dansylcadaverine (Monodansyl cadaverine)
    CAS: 10121-91-2
    纯度: >98.00% / >97.00%

    A fluorescent marker for autophagic vacuoles

  • GC30158 structure
    GC30158p38-α MAPK-IN-1
    CAS: 443913-15-3
    纯度: >99.50%

    p38-α MAPK-IN-1 is an inhibitor of p38-α, with IC50 value of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.

  • GC30263 structure
    GC30263Glucosamine (D-Glucosamine)
    CAS: 3416-24-8
    纯度: >98.00%

    Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine(GS) treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.

  • GC30343 structure
    GC30343Selenomethionine (Seleno-DL-methionine)
    CAS: 1464-42-2
    纯度: >98.00%

    硒代蛋氨酸(Seleno-DL-methionine)是一种天然存在的含硒氨基酸,是硒的常见天然食物来源。

  • GC30356 structure
    GC30356Metofenazate (Methophenazine)
    CAS: 388-51-2

    Metofenazate (Methophenazine) 是一种选择性钙调蛋白抑制剂。

  • GC30360 structure
    GC30360Cresol (Cresol mixture of isomers)
    CAS: 1319-77-3

    Cresol是一种有机化合物,是芳香族有机化合物广泛存在的天然及合成基团。

  • GC30366 structure
    GC30366FAAH-IN-2
    CAS: 184475-71-6
    纯度: >99.40%

    FAAH-IN-2是摘自专利WO/2008/100977A2中的FAAH抑制剂。

  • GC30537 structure
    GC30537BPO-27 racemate
    CAS: 1314873-02-3
    纯度: >98.00%

    BPO-27racemate是有效的CFTR抑制剂,IC50值为8nM。

  • GC30565 structure
    GC30565BAR502
    CAS: 1612191-86-2
    纯度: >98.00%

    A dual agonist of GP-BAR1 and FXR

  • GC30608 structure
    GC30608Ipsalazide
    CAS: 82101-17-5

    Ipsalazide是一种新的柳氮磺吡啶类似物,旨在释放胃肠道中的5-氨基水杨酸和无毒载体分子。

  • GC30609 structure
    GC30609p38 MAPK-IN-2
    CAS: 635725-16-5

    p38MAPK-IN-2是一种p38kinase的抑制剂。

  • GC30646 structure
    GC30646Skatole(3-Methylindole)
    CAS: 83-34-1
    纯度: >99.50%

    Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

  • GC30676 structure
    GC30676MAPK13-IN-1
    CAS: 229002-10-2
    纯度: >98.00%

    MPAK13-IN-1是MAPK13(p38δ)的一个抑制剂,其IC50值为620nM。

  • GC30744 structure
    GC30744Norepinephrine (Adrenor)
    CAS: 51-41-2
    纯度: >98.00%

    (-)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.

  • GC30751 structure
    GC30751FAAH-IN-1
    CAS: 1242441-47-9

    FAAH-IN-1是脂肪酸酰胺水解酶(FAAH)抑制剂,对大鼠和人FAAH的IC50值分别为145nM和650nM。

  • GC30761 structure
    GC30761α-Hydroxylinoleic acid
    CAS: 57818-44-7
    纯度: >98.00%

    ABTL0812 (α-Hydroxylinoleic acid, LP-10218, SCLN-0812) inhibits Akt/mTOR axis by inducing the overexpression of TRIB3 and activating autophagy in lung squamous carcinoma cell lines. ABTL0812 also induces AMPK activation and ROS accumulation.