E3 Ligase
E3 Ligase(E3 连接酶)
E3 ligases perform the last step in the ubiquitination cascade. They transfer the ubiquitin from the active site cysteine of E2 enzyme to the substrate lysine or N terminus. The loss of function or mis-targeting of the E3 ligases are associated with various cancer types.
E3 Ligase 相关产品(7)
- GC250195-amino-2,4-dimethylpyridine (5A-DMP)CAS: 1193-71-1
5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC10940 | PRT 4165 | 31083-55-3 | >98.50% | |
An inhibitor of PRC1 ubiquitin ligases | ||||
| GC11869 | SZL P1-41 | 222716-34-9 | >98.00% | |
SZL P1-41是一种特异性S期激酶相关蛋白2（Skp2）抑制剂。 | ||||
| GC15017 | NSC 624206 | 13116-77-3 | - | |
An inhibitor of ubiquitin-activating enzyme (E1) | ||||
| GC15492 | SMER 3 | 67200-34-4 | >98.00% | |
SMER 3是一种选择性抑制SCFMet30泛素E3连接酶的小分子化合物。 | ||||
| GC25019 | 5-amino-2,4-dimethylpyridine (5A-DMP) | 1193-71-1 | - | |
5-amino-2,4-dimethylpyridine (5A-DMP) is a novel tandem Tudor domain (TTD)-binding compound that inhibits the full-length UHRF1:LIG1 interaction in Xenopus egg extracts | ||||
| GC44291 | NAB 2 | 1504588-00-4 | >98.00% | |
An inhibitor of α-synuclein-induced toxicity | ||||
| GC50234 | N106 | 862974-25-2 | - | |
An activator of SERCA2A sumoylation | ||||