MAPK Signaling

MAPK Signaling(MAPK信号通路)

研究方向

MAPK Signaling 相关产品(575)

  • GN10752 structure
    GN10752Pachymic acid
    CAS: 29070-92-6
    纯度: >98.00%

    A triterpenoid with diverse biological activities

  • GN10784 structure
    GN10784Rhoifolin
    CAS: 17306-46-6
    纯度: >98.00%

    A flavonoid glycoside with diverse biological activities

  • GN10804 structure
    GN10804Isovitexin
    CAS: 38953-85-4 ; 29702-25-8
    纯度: >98.00%

    Isovitexin是从水稻稻壳中提取的一种物质,具有多种生物活性,包括抗炎和抗氧化活性。

  • GN10814 structure
    GN10814Quercitrin
    CAS: 522-12-3
    纯度: >98.00%

    A flavonoid glycoside

  • GC10074 structure
    GC10074H 89 2HCl
    CAS: 130964-39-5
    纯度: >98.00%

    H-89 2HCl 是一种有效的选择性 camp 依赖性蛋白激酶 A 抑制剂,IC50 值为 48 nM,对 PKG、PKC、酪蛋白激酶和其他激酶表现出较弱的抑制作用 。

  • GC10209 structure
    GC10209TAK-733
    CAS: 1035555-63-5
    纯度: >99.00%

    A MEK1 inhibitor

  • GC11488 structure
    GC11488TCS JNK 5a
    CAS: 312917-14-9
    纯度: >98.00%

    A selective inhibitor of JNK2 and JNK3

  • GC12141 structure
    GC12141RO4987655
    CAS: 874101-00-5
    纯度: >99.00%

    A MEK inhibitor

  • GC13529 structure
    GC13529CC-401
    CAS: 395104-30-0

    A potent, specific pan-JNK inhibitor

  • GC14247 structure
    GC14247GDC-0623
    CAS: 1168091-68-6
    纯度: >98.00%

    A potent, ATP-uncompetitive inhibitor of MEK1

  • GC16872 structure
    GC16872Refametinib
    CAS: 923032-37-5
    纯度: >99.50%

    An allosteric inhibitor of MEK1/2

  • GC17031 structure
    GC17031VRT752271
    CAS: 869886-67-9
    纯度: >99.50%

    VRT752271 (BVD-523; VRT752271) 是一种有效的、具有口服活性、高度选择性、ATP 竞争性和可逆的 ERK1/2 激酶共价抑制剂,对 ERK2 的 IC50 <0.3 nM。 VRT752271 (BVD-523; VRT752271) 抑制 A375 黑色素瘤细胞系中的磷酸化 ERK2 (pERK) 和下游激酶 RSK (pRSK)。

  • GC10647 structure
    GC10647FR 180204
    CAS: 865362-74-9
    纯度: >98.00%

    FR 180204是一种选择性的ERK抑制剂,对ERK1和ERK2的IC 50 值分别为0.51μM和0.33μM。

  • GC13001 structure
    GC13001SB 203580 hydrochloride
    CAS: 869185-85-3
    纯度: >98.00%

    A water soluble p38 MAPK inhibitor

  • GC10054 structure
    GC10054SB 239063
    CAS: 193551-21-2
    纯度: >99.50%

    A selective p38 MAPK inhibitor

  • GC13968 structure
    GC13968SB202190 (FHPI)
    CAS: 152121-30-7
    纯度: >99.50% / >99.00%

    SB 202190是一种选择性p38 MAP激酶抑制剂,对p38α和p38β2的IC50分别为50 nM和100 nM。

  • GC10204 structure
    GC10204AEG 3482
    CAS: 63735-71-7
    纯度: >99.00%

    An inhibitor of p75 NTR - and NRAGE-induced apoptosis

  • GC10534 structure
    GC10534B-Raf IN 1
    CAS: 950736-05-7
    纯度: >98.50%

    An inhibitor of B-RAF and C-RAF

  • GC12321 structure
    GC12321PKI 14-22 amide, myristoylated
    CAS: 201422-03-9

    A PKA inhibitor

  • GC12674 structure
    GC12674IQ 3
    CAS: 312538-03-7
    纯度: >98.50%

    IQ 3 是 c-Jun N-末端激酶 (JNK) 家族的特异性抑制剂,优先考虑 JNK3。

  • GC12904 structure
    GC12904BI 78D3
    CAS: 883065-90-5
    纯度: >99.00%

    A competitive inhibitor of JNK

  • GC13717 structure
    GC13717Losmapimod
    CAS: 585543-15-3
    纯度: >98.00%

    A dual p38α and p38β MAPK inhibitor

  • GC14648 structure
    GC14648KT 5720
    CAS: 108068-98-0
    纯度: >98.00%

    A potent inhibitor of PKA