GlpBio

RSK

RSK(核糖体S6激酶)

RSK (ribosomal s6 kinase) is a family of protein kinases involved in signal transduction.

RSK 相关产品(32)

  • GC16313 structure
    GC16313SL 0101-1
    CAS: 77307-50-7

    A selective inhibitor of RSK

  • GC16779 structure
    GC16779BRD 7389
    CAS: 376382-11-5

    An inhibitor of RSKs

  • GC10689 structure
    GC10689PF-4708671
    CAS: 1255517-76-0
    纯度: >99.50%

    PF-4708671 是一种新型的细胞渗透性 S6K1 抑制剂，特异性抑制 S6K1 亚型，Ki 为 20 nM，IC50 为 160 nM。

  • GC10918 structure
    GC10918AT7867 dihydrochloride
    CAS: 1431697-86-7
    纯度: >99.00%

    A potent and orally bioavailable pan-Akt inhibitor

  • GC12089 structure
    GC12089LY2584702
    CAS: 1082949-67-4
    纯度: >98.00%

    A p70S6K inhibitor

  • GC12297 structure
    GC12297AT7867
    CAS: 857531-00-1
    纯度: >98.00%

    A potent and orally bioavailable pan-Akt inhibitor

  • GC12982 structure
    GC12982BIX 02565
    CAS: 1311367-27-7
    纯度: >99.00%

    A RSK2 inhibitor with multiple off target effects

  • GC13468 structure
    GC13468BI-D1870
    CAS: 501437-28-1
    纯度: >99.00%

    An inhibitor of RSK1-4

  • GC14125 structure
    GC14125FMK
    CAS: 821794-92-7
    纯度: >98.00%

    An inhibitor of RSK2

  • GC14693 structure
    GC14693CMK
    CAS: 821794-90-5
    纯度: >99.50%

    CMK 是一种 RSK2 激酶抑制剂，与 FMK 相比，具有相似的效力，但化学稳定性较低。

  • GC15240 structure
    GC15240APS-2-79
    CAS: 2002381-31-7
    纯度: >99.00%

    An inhibitor of KSR-dependent MAPK signaling

  • GC16039 structure
    GC16039LJH685
    CAS: 1627710-50-2
    纯度: >98.00%

    An inhibitor of RSKs

  • GC16601 structure
    GC16601LJI308
    CAS: 1627709-94-7
    纯度: >99.00%

    An inhibitor of RSKs

  • GC17407 structure
    GC17407Pluripotin
    CAS: 839707-37-8
    纯度: >98.50%

    A synthetic compound that promotes self-renewal of murine embryonic stem cells

  • GC17712 structure
    GC17712AT13148
    CAS: 1056901-62-2
    纯度: >99.50%

    A multi-AGC kinase inhibitor

  • GC32797 structure
    GC32797AD80
    CAS: 1384071-99-1
    纯度: >99.50%

    AD80, a multikinase inhibitor, shows strong activity against human RET (c-RET), BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR. The IC50 value for RET is 4 nM.

  • GC34197 structure
    GC34197FMK-MEA
    CAS: 1414811-15-6

    FMK-MEA 是一种有效的选择性 p90 核糖体 S6 激酶 (RSK) 抑制剂。

  • GC36505 structure
    GC36505LY-2584702 hydrochloride
    CAS: 1082948-81-9

    LY2584702 is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Phase 1.

  • GC38755 structure
    GC38755CKI-7
    CAS: 120615-25-0
    纯度: >99.00%

    A CK1 inhibitor

  • GC38791 structure
    GC38791GSK-25
    CAS: 874119-56-9
    纯度: >99.50%

    GSK-25 是一种有效的、选择性的，具有口服活性的 ROCK1 抑制剂 (IC50=7 nM)。GSK-25 对 31 种激酶以及 RSK1 和 p70S6K 保持良好的选择性 (RSK1: IC50=398 nM, p70S6K: IC50=1 μM)。GSK-25 可抑制 P450 (CYP2C9、CYP2D6、CYP3A4的IC50 分别为2.5、5.2、2.5 μM)。

  • GC39715 structure
    GC39715M2698
    CAS: 1379545-95-5
    纯度: >99.50%

    A dual inhibitor of p70S6K and Akt1

  • GC43803 structure
    GC43803HA-1077 (hydrochloride)
    CAS: 203911-27-7
    纯度: >98.00%

    A ROCK inhibitor

  • GC44095 structure
    GC44095LY2584702 (tosylate)
    CAS: 1082949-68-5
    纯度: >99.00%

    LY2584702 (tosylate)是一种强效、高选择性的p70 S6激酶的ATP竞争性抑制剂，属于磷脂酰肌醇-3-激酶信号通路的下游组分，IC 50 值为0.004μM。

  • GC49763 structure
    GC49763S6K-18
    CAS: 1265789-88-5
    纯度: >98.00%

    A p70S6K1 inhibitor