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Endocrinology and Hormones

Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

研究方向

Endocrinology and Hormones 相关产品(940)

  • GC11885 structure
    GC11885Sevelamer HCl
    CAS: 152751-57-0
    纯度: >98.00%

    Sevelamer HCl 是一种磷酸盐结合药物，用于治疗慢性肾病患者的高磷血症；由与环氧氯丙烷交联的聚烯丙胺组成。

  • GC11957 structure
    GC11957RD162
    CAS: 915087-27-3

    A second-generation androgen receptor antagonist

  • GC11996 structure
    GC11996Ospemifene
    CAS: 128607-22-7
    纯度: >99.50%

    A selective estrogen receptor modulator

  • GC12072 structure
    GC12072CD 2665
    CAS: 170355-78-9
    纯度: >98.00%

    A selective RARβ and RARγ antagonist

  • GC12140 structure
    GC12140Endoxifen
    CAS: 112093-28-4

    Endoxifen Z-异构体是最重要的他莫昔芬代谢物，负责在表达雌激素受体-α (ERα) 的乳腺癌细胞中引发该药物的抗雌激素作用。

  • GC12271 structure
    GC12271Bicalutamide
    CAS: 90357-06-5
    纯度: >98.00%

    Bicalutamide是一种非甾体抗雄激素药物，可通过选择性和竞争性地阻断雄激素与雄激素受体（AR）的结合，在外周组织中发挥抗雄激素作用。

  • GC12294 structure
    GC12294LE 135
    CAS: 155877-83-1
    纯度: >99.00%

    A RARβ antagonist

  • GC12385 structure
    GC12385MDV3100 (Enzalutamide)
    CAS: 915087-33-1
    纯度: >99.50%

    MDV3100(enzalutamide) 是第二代 AR 拮抗剂，在 LNCaP 前列腺细胞中的 IC50 为 36nM。

  • GC12409 structure
    GC12409Liothyronine Sodium
    CAS: 55-06-1
    纯度: >99.00%

    Liothyronine sodium 是一种强效的甲状腺激素受体TRα和TRβ激动剂，其 Ki 值为 2.33nM。

  • GC12445 structure
    GC12445TFM-4AS-1
    CAS: 188589-61-9

    androgen receptor modulator

  • GC12577 structure
    GC12577ER 50891
    CAS: 187400-85-7

    ER-50891 是一种有效的视黄酸受体 α(RARα) 拮抗剂。 ER-50891 显着减弱 ATRA 对 BMP 2 诱导的成骨细胞生成的抑制作用。

  • GC12644 structure
    GC12644Quinestrol
    CAS: 152-43-2
    纯度: >98.00%

    A synthetic estrogen

  • GC12766 structure
    GC12766G-1
    CAS: 881639-98-1
    纯度: >99.50%

    G-1 is a selective and potent agonist of GPR30 with EC50 value about 2 nM.

  • GC12767 structure
    GC12767Zearalenone
    CAS: 17924-92-4
    纯度: >98.50% / >98.00%

    Zearalenone是一种雌激素样镰刀菌毒素，可与包括17β-雌二醇特异性亚型在内的雌激素受体结合。

  • GC12791 structure
    GC127913,3'-Diindolylmethane
    CAS: 1968-05-4
    纯度: >98.00%

    A phytochemical with antiradiation and chemopreventative effects

  • GC12890 structure
    GC12890α-Naphthoflavone
    CAS: 604-59-1
    纯度: >99.00%

    A flavone that modulates xenobiotic metabolism

  • GC12903 structure
    GC12903Sobetirome
    CAS: 211110-63-3
    纯度: >98.00%

    Sobetirome是一种甲状腺激素受体β（TRβ）选择性激动剂，对TRβ-1的EC 50 为0.16μM。

  • GC12933 structure
    GC12933RU 58841
    CAS: 154992-24-2
    纯度: >99.50%

    A non-steroidal antiandrogen

  • GC12938 structure
    GC12938PF 998425
    CAS: 1076225-27-8
    纯度: >98.00%

    A non-steroidal androgen receptor antagonist

  • GC13196 structure
    GC13196NVP-QAV680
    CAS: 872365-16-7

    potent and selective CRTh2 receptor antagonist

  • GC13199 structure
    GC13199UVI 3003
    CAS: 847239-17-2
    纯度: >98.00%

    A pan-RXR antagonist

  • GC13309 structure
    GC13309WAY 200070
    CAS: 440122-66-7
    纯度: >99.00%

    A potent and selective ERβ agonist

  • GC13373 structure
    GC13373(R)-DPN
    CAS: 524047-78-7

    R)-DPN (compound 3) 是一种选择性 ERβ 配体，对 ERα 和 ERβ 的 EC50 分别为 2.9 和 0.8 nM。

  • GC13431 structure
    GC1343124α-methyl Cholesterol
    CAS: 474-62-4
    纯度: >98.00%

    A phytosterol