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Endocrinology and Hormones

Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

研究方向

Endocrinology and Hormones 相关产品(940)

  • GC13680 structure
    GC13680SR-9243
    CAS: 1613028-81-1
    纯度: >99.50%

    An LXR inverse agonist

  • GC13685 structure
    GC13685Andarine
    CAS: 401900-40-1
    纯度: >99.50%

    A selective androgen receptor modulator

  • GC13887 structure
    GC1388725(R)-27-hydroxy Cholesterol
    CAS: 20380-11-4
    纯度: >98.00%

    25(R)-27-hydroxy Cholesterol是肝脏X受体（LXR）α和LXRβ的激动剂，EC 50 值分别为0.085μM和0.071μM。

  • GC13917 structure
    GC139174’-hydroxy Tamoxifen
    CAS: 82413-23-8
    纯度: ≥98% (may contain up to 10% of the (E) isomer)

    An active tamoxifen metabolite

  • GC13954 structure
    GC13954LXR-623
    CAS: 875787-07-8
    纯度: >99.50%

    An LXR modulator

  • GC13959 structure
    GC13959Adarotene
    CAS: 496868-77-0
    纯度: >99.00%

    An atypical retinoid

  • GC13984 structure
    GC13984Tamibarotene
    CAS: 94497-51-5
    纯度: >99.50%

    A selective RARα agonist

  • GC14131 structure
    GC14131FERb 033
    CAS: 1111084-78-6

    FERb 033 是一种选择性有效的 ERβ 激动剂（Ki=7.1 nM，EC50=4.8 nM）。

  • GC14158 structure
    GC14158Obeticholic Acid
    CAS: 459789-99-2
    纯度: >98.00%

    Obeticholic Acid（奥贝胆酸；INT-747；6-ECDCA；6-Ethylchenodeoxycholic acid）是一种有效的，选择性的和口服活性的法尼醇X受体（FXR ）激动剂，EC 50 为99nM。

  • GC14185 structure
    GC14185BMS 753
    CAS: 215307-86-1

    A synthetic retinoid and RARα agonist

  • GC14221 structure
    GC14221HE-3235
    CAS: 183387-50-0

    Androgen receptor antagonist

  • GC14273 structure
    GC14273TTNPB (Arotinoid Acid)
    CAS: 71441-28-6
    纯度: >99.00%

    A potent, selective RAR agonist

  • GC14304 structure
    GC14304Palovarotene
    CAS: 410528-02-8
    纯度: >99.00%

    A RARγ agonist

  • GC14370 structure
    GC14370Propyl pyrazole triol (PPT)
    CAS: 263717-53-9
    纯度: >98.00%

    Propyl pyrazole triol (PPT)是一种选择性雌激素受体α（ERα）激动剂，可通过在神经系统激活ERα，保护神经元免受氧化应激与炎症损伤。

  • GC14379 structure
    GC14379Adapalene sodium salt
    CAS: 911110-93-5

    An RARβ and RARγ agonist

  • GC14405 structure
    GC14405AZD9496
    CAS: 1639042-08-2
    纯度: >99.00%

    A SERD

  • GC14511 structure
    GC14511All-trans Retinal
    CAS: 116-31-4
    纯度: >98.00%

    All-trans Retinal 是一种具有活性的vitamin A aldehyde，对CRBP-I和CRBP-II蛋白的K d 值分别为50nM和90nM。

  • GC14560 structure
    GC14560Cl-4AS-1
    CAS: 188589-66-4

    Cl-4AS-1 是一种有效的甾体雄激素受体 (AR) 激动剂 (IC50 = 12 nM)，也是 5α-还原酶 I 型和 II 型的抑制剂（IC50 分别为 6 和 10 nM）。

  • GC14596 structure
    GC145969-cis-Retinoic Acid
    CAS: 5300-03-8
    纯度: ≥90.00%

    9-cis-Retinoic Acid是一种对视黄酸受体(RAR)具有高亲和力的配体，对RARα的EC 50 值为0.2μM。

  • GC14638 structure
    GC14638SR9238
    CAS: 1416153-62-2
    纯度: >99.50%

    A liver-specific inverse agonist of LXR

  • GC14902 structure
    GC14902G-36
    CAS: 1392487-51-2
    纯度: >98.00%

    G-36是一种具有细胞渗透性的G蛋白偶联雌激素受体（GPER/GPR30）拮抗剂，可抑制雌激素介导的钙动员（IC 50 =112nM）。

  • GC14972 structure
    GC1497222(R)-hydroxy Cholesterol
    CAS: 17954-98-2
    纯度: >98.00% / >99.50%

    22(R)-hydroxy Cholesterol是一种肝X受体（LXR）的内源性激动剂，其EC 50 值为325nM。

  • GC15001 structure
    GC15001Tiratricol
    CAS: 51-24-1
    纯度: >99.50% / >98.00%

    A thyroid hormone receptor agonist

  • GC15382 structure
    GC15382Isotretinoin
    CAS: 4759-48-2
    纯度: >99.50%

    A retinoid