Ubiquitination/ Proteasome
Ubiquitination/ Proteasome(泛素化/蛋白酶体)
Ubiquitination/ Proteasome 相关产品(1292)
- GC33779Cysteamine (β-Mercaptoethylamine)CAS: 60-23-1纯度: >95.00%
2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.
- GC33833Tetrahydrocurcumin (HZIV 81-2)CAS: 36062-04-1
A metabolite of curcumin with diverse biological activities
- GC33848Fludrocortisone acetate (9α-Fludrocortisone acetate)CAS: 514-36-3纯度: >99.50%
A mineralocorticoid agonist
- GC34009Nitroprusside disodium dihydrate (Sodium nitroprusside dihydrate)CAS: 13755-38-9纯度: >99.50% / >99.00%
Sodium Nitroprusside Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood.
- GC34010Danshensu (Dan shen suan A)CAS: 76822-21-4纯度: >98.00%
丹参素是丹参的一种活性成分，通过激活 Nrf2 信号通路显示出广泛的心血管益处。
- GC34014Trimetazidine dihydrochlorideCAS: 13171-25-0纯度: >99.50%
Trimetazidine dihydrochloride是一种亲脂性piperazine衍生物，用于治疗心绞痛。
- GC34057TBHQ (tert-Butylhydroquinone)CAS: 1948-33-0纯度: >99.50%
TBHQ(tert-Butylhydroquinone)是一种强效的酚类抗氧化剂，能够减轻氧化应激和炎症反应。
- GC34096(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid))CAS: 866541-93-7纯度: >98.00%
(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid))是一种新型的、具有口服活性的Bcl-2家族蛋白抑制剂，可抑制Bcl-2（K i =260±30nM），Mcl-1（K i =170±10nM）和Bcl-xL（K i =480±40nM）。
- GC34390Autocamtide 2, amide纯度: >99.00%
Autocamtide2,amide是钙调蛋白激酶(CaMK)家族实验的底物(100μMfinalconcentration)。
- GC34532CFTR corrector 2CAS: 1628416-28-3纯度: >99.50%
FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein.
- GC34817Sulfosuccinimidyl oleate sodiumCAS: 1212012-37-7纯度: >95.00% / >98.00%
Sulfosuccinimidyl oleate sodium是一种不可逆的CD36抑制剂。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC33779 | Cysteamine (β-Mercaptoethylamine) | 60-23-1 | >95.00% | |
2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine. | ||||
| GC33833 | Tetrahydrocurcumin (HZIV 81-2) | 36062-04-1 | - | |
A metabolite of curcumin with diverse biological activities | ||||
| GC33848 | Fludrocortisone acetate (9α-Fludrocortisone acetate) | 514-36-3 | >99.50% | |
A mineralocorticoid agonist | ||||
| GC34009 | Nitroprusside disodium dihydrate (Sodium nitroprusside dihydrate) | 13755-38-9 | >99.50% / >99.00% | |
Sodium Nitroprusside Dihydrate is a potent vasodilator working through releasing NO spontaneously in blood. | ||||
| GC34010 | Danshensu (Dan shen suan A) | 76822-21-4 | >98.00% | |
丹参素是丹参的一种活性成分，通过激活 Nrf2 信号通路显示出广泛的心血管益处。 | ||||
| GC34014 | Trimetazidine dihydrochloride | 13171-25-0 | >99.50% | |
Trimetazidine dihydrochloride是一种亲脂性piperazine衍生物，用于治疗心绞痛。 | ||||
| GC34035 | Meglutol (Dicrotalic acid) | 503-49-1 | >98.00% | |
An HMG-CoA reductase inhibitor | ||||
| GC34057 | TBHQ (tert-Butylhydroquinone) | 1948-33-0 | >99.50% | |
TBHQ(tert-Butylhydroquinone)是一种强效的酚类抗氧化剂，能够减轻氧化应激和炎症反应。 | ||||
| GC34072 | Talmapimod (SCIO-469) | 309913-83-5 | >98.00% | |
A p38 MAPK inhibitor | ||||
| GC34094 | Mycro 3 | 944547-46-0 | >99.00% | |
Mycro 3 is a potent and selective inhibitor of c-Myc in whole cell assays. Mycro 3 also shows weak inhibitory activity against AP-1. | ||||
| GC34096 | (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) | 866541-93-7 | >98.00% | |
(R)-(-)-Gossypol acetic acid (AT-101 (acetic acid))是一种新型的、具有口服活性的Bcl-2家族蛋白抑制剂，可抑制Bcl-2（K i =260±30nM），Mcl-1（K i =170±10nM）和Bcl-xL（K i =480±40nM）。 | ||||
| GC34117 | SMER18 | 944153-47-3 | - | |
SMER18是Rapamycin的一种小分子增强剂,充当mTOR非依赖性的的自噬诱导剂。 | ||||
| GC34173 | LG-100064 | 153559-46-7 | >99.50% | |
LG-100064是一种类视黄醇X受体(retinoid-X-receptor(RXR))激动剂，对RXRα，RXRβ和RXRγ的EC50值分别为330nM，200nM和260nM；LG-100064可用于癌症研究。 | ||||
| GC34315 | ULK-101 | 2443816-45-1 | >99.50% | |
ULK-101是一种选择性的ULK1（ IC 50 =1.6nM）抑制剂，还可抑制 ULK2（ IC 50 =30nM）的活性。 | ||||
| GC34330 | XRK3F2 | 2375193-43-2 | >95.00% / >98.50% | |
XRK3F2 is an inhibitor of the p62-ZZ domain that blunts MM-induced Runx2 suppression in vitro, and induces new bone formation and remodeling in the presence of tumor in vivo. | ||||
| GC34390 | Autocamtide 2, amide | - | >99.00% | |
Autocamtide2,amide是钙调蛋白激酶(CaMK)家族实验的底物(100μMfinalconcentration)。 | ||||
| GC34532 | CFTR corrector 2 | 1628416-28-3 | >99.50% | |
FDL169 is a CFTR corrector that is designed to fix and restore the function of the defective CFTR protein. | ||||
| GC34649 | LMP7-IN-1 | 2285330-15-4 | >98.00% | |
LMP7-IN-1 是一种可口服的、有效的、可逆的和高度选择性的免疫蛋白酶体亚基 LMP7 (β5i) 抑制剂。 LMP7-IN-1 对 LMP7 亚基具有高生化 (IC50=3.6 nM) 和细胞 (IC50=3.4 nM) 效力。 LMP7-IN-1 在多发性骨髓瘤异种移植模型中显示出强大的抗肿瘤功效。 LMP7-IN-1 可显着长期抑制肿瘤 LMP7 活性和泛素化蛋白转换，并诱导多发性骨髓瘤细胞凋亡。 | ||||
| GC34686 | Nidufexor | 1773489-72-7 | >98.50% | |
An FXR partial agonist | ||||
| GC34745 | PTI-428 | 1953130-87-4 | >99.50% | |
PTI-428是一种可增强并稳定囊性纤维化跨膜传导调节因子（CFTR）蛋白功能的特异性调节剂。 | ||||
| GC34817 | Sulfosuccinimidyl oleate sodium | 1212012-37-7 | >95.00% / >98.00% | |
Sulfosuccinimidyl oleate sodium是一种不可逆的CD36抑制剂。 | ||||
| GC34849 | UBCS039 | 358721-70-7 | >98.50% | |
UBCS039 is the first synthetic SIRT6 activator with EC50 of 38 μM,induces a time-dependent activation of autophagy in several human tumor cell lines. | ||||
| GC34862 | WYC-209 | 2131803-90-0 | >99.50% | |
WYC-209是一种合成类视黄醇，能抑制恶性小鼠黑色素瘤肿瘤再生细胞(TRC)的增殖，IC50值为0.19μM。WYC-209主要细胞靶点是维甲酸受体(RARs)。 | ||||
| GC34918 | MW-150 dihydrochloride dihydrate | 1661020-92-3 | - | |
An inhibitor of p38α MAPK | ||||