Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for Endogenous Metabolite

Cat.No. 产品名称 Information
GC41778 1,2,3-Tripalmitoyl-rac-glycerol
(三)棕榈酸甘油酯
A triacylglycerol
GC41774 1,2,3-Trimyristoyl-rac-glycerol
三肉豆蔻酸甘油酯
A triacylglycerol
GC41768 1,2,3-Tridecanoyl-rac-glycerol
甘油三癸酸酯; Tricaprin; Glyceryl tridecanoate
A triacylglycerol
GC41767 1,2,3-Triarachidonoyl-rac-glycerol
三花生精
A triacylglycerol
GC41765 1,2,3-Tri-13(Z)-Docosenoyl-rac-glycerol
三芥精
A triacylglycerol
GC41721 (R)-α-Lipoic Acid
硫辛酸; (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid
A cyclic disulfide antioxidant
GC41670 (±)-Epinephrine (hydrochloride)
肾上腺素盐酸盐
(±)-Epinephrine (hydrochloride)是一种肾上腺素能受体激动剂，在低剂量时，主要激活β受体，增强支气管扩张和心脏活动；而在高剂量时，(±)-Epinephrine (hydrochloride)会与α受体结合，引起血管收缩并增加血管张力。
GC41586 cis-Petroselinic Acid
岩芹酸；芹子酸；岩芹炔酸；十八碳 6 烯酸
A monounsaturated fatty acid
GC41478 L-α-Hydroxyglutaric Acid
S-2-羟基戊二酸,2(S)-HG, 2(S)-Hydroxyglutaric Acid, L-2-HG, L-2-Hydroxyglutaric Acid
L-α-羟基戊二酸是生命各个领域的重要代谢产物。
GC41477 3-Hydroxyglutaric Acid
3-羟基戊二酸
A biomarker for GCDH deficiency
GC41390 Aldosterone
醛固酮

醛固酮是由肾上腺皮质分泌的一种类固醇激素，是控制钠和钾平衡的主要矿物质皮质激素
GC41362 OMDM-1
(S)Noleoyl Tyrosinol
An inhibitor of AEA uptake
GC41283 N-acetyl-D-Glucosamine
N-乙酰-D-氨基葡萄糖; N-Acetyl-2-amino-2-deoxy-D-glucose
N-acetyl-D-Glucosamine（GlcNAc）是葡萄糖的单糖衍生物，具有抗肿瘤和抗炎活性。
GC41282 2'-O-Methyladenosine
2'-O-甲基腺苷
An adenosine analog
GC41183 α-Carotene
α-胡萝卜素

A precursor of vitamin A
GC41003 4'-O-methyl Quercetin
柽柳黄素,4'-O-Methyl Quercetin
A flavonoid with anticancer and antiplasmodial activity
GC40994 N-Methylnicotinamide
N-甲基烟酰胺
An isomer of nicotinamide
GC40928 Trimethylamine N-oxide
三甲胺N-氧化物

A metabolite of choline, phosphatidylcholine, and L-carnitine
GC40926 8-Hydroxy-2'-deoxyguanosine
8-OH-脱氧鸟嘌呤,8-OHdG
8-Hydroxy-2'-deoxyguanosine是氧化应激诱导的DNA损伤的关键生物标志物，用于评估多种癌症和退行性疾病的风险。
GC40913 Glycohyodeoxycholic Acid
甘氨猪去氧胆酸
A metabolite of hyodeoxycholic acid
GC40794 Sphinganine (d18:0)
D-赤式-C18-二氢-D-神经鞘氨醇
Sphinganine (d18:0)是一种鞘脂代谢途径的中间体。
GC40777 β-D-Glucose
D-无水葡萄糖
A cyclic monosaccharide
GC40743 3-deoxy Galactosone
3-脱氧-山梨糖酮
A galactose degradation product
GC40730 11-cis Vaccenyl Acetate Male mating pheromone of D. melanogaster
GC40719 β-Muricholic Acid
Β-鼠胆酸,5β-Cholanic Acid-3α,6β,7β-triol, β-MCA
β-胆酸β-muricholic acid是一种天然存在的三羟基亲水性胆汁酸，作为胆道胆固醇去饱和剂，促进胆固醇胆结石的溶解。
GC40718 α-Muricholic Acid
5β-Cholanic Acid-3α,6β,7α-triol
A murine-specific primary bile acid
GC40661 D-Carnitine
右旋肉碱
An isomer of L-carnitine
GC40620 Heneicosanoic Acid
二十一碳酸
A very long-chain saturated fatty acid
GC40612 Resolvin E1
RvE1

A specialized pro-resolving mediator
GC40495 DL-Mevalonolactone
甲瓦龙酸内酯,(±)-Mevalonolactone; Mevalolactone
A precursor in the mevalonate pathway
GC40442 (±)8-HETE
(±)8-Hydroxyeicosatetraenoic Acid
A monohydroxy fatty acid produced by the non-enzymatic oxidation of arachidonic acid
GC40399 Linoelaidic Acid
亚麻酸; Linoelaidic acid
An all-trans fatty acid homolog of linoleic acid
GC40394 11-deoxy Corticosterone
去氧皮质酮
11-deoxy Corticosterone是一种由肾上腺产生的类固醇激素，具有盐皮质激素活性，并作为醛固酮的前体。
GC10559 Erythrodiol
高根二醇,Oleanolic alcohol; olean-12-ene-3,28-diol; ERYTHODIOL; Erythrodiol; 12-OLEANENE-3,28-DIOL; HOMOOLESTRANOL;
A triterpene with diverse biological activities
GC10456 Fucosterol
岩皂甾醇,24-ethylidene Cholesterol
A natural phytosterol with diverse biological activities
GC34914 LysoPC(14:0/0:0)
1-十四酰-2-羟基卵磷脂
A lysophospholipid
GC34881 5-Methyltetrahydrofolic acid
甲基叶酸盐,5-Methyl THF
5-Methyltetrahydrofolicacid是一种具有生物活性的叶酸形式。5-Methyltetrahydrofolicacid是四氢叶酸的甲基化衍生物。5-Methyltetrahydrofolicacid是主要的天然膳食叶酸，是血浆和脑脊液中叶酸的主要形式。
GC34609 Guanosine 5'-diphosphate disodium salt
鸟苷-5'-二磷酸二钠盐,GDP disodium salt
Guanosine 5'-diphosphate disodium salt作为一种关键的核苷二磷酸，通过G蛋白信号转导作为细胞内信号级联反应的调节剂。
GC34442 (R)-(+)-Citronellal
(R)-(+)-香茅醛; (+)-Citronellal
(R)-(+)-Citronellal可从柑橘、薰衣草和桉树油中分离得到，是一种单萜化合物，是香茅醛的主要成分，具有独特的柠檬香味。是一种调味剂。可用于驱虫和抗真菌。
GP24734 Streptolysin-O 链球菌溶血素-O 化脓性链球菌重组体
GC19495 DL-Folinic Acid (calcium salt)
亚叶酸钙; Leucovorin calcium; Calcium folinate
A reduced folic acid
GC40183 1-Oleoyl Glycerol
甘油单油酸酯
A monoacylglycerol
GC40097 4-HOBA
4-羟基苄胺
An isomer of 2-HOBA
GC40087 7α-hydroxy-4-Cholesten-3-one
7-羟基-4-胆甾烯-3-酮
7α-Hydroxy-4-cholesten-3-one是一种由胆固醇合成胆汁酸的中间体，是pregnane X receptor（PXR）激动剂。
GC40038 Heptanoyl-L-carnitine (chloride)
C7:0 Carnitine, CAR 7:0, L-Carnitine heptanoyl ester, L-Heptanoylcarnitine
Heptanoyl-L-carnitine (chloride)是L-肉碱的衍生物，L-肉碱是一种在脂肪酸转运至线粒体进行β-氧化过程中发挥关键作用的化合物。Heptanoyl-L-carnitine (chloride)在生物化学研究中被广泛用于研究代谢过程和线粒体功能。
GC40037 Linoleoyl-L-carnitine (chloride)
CAR 18:2, C18:2 Carnitine, L-Carnitine linoleoyl ester, L-Linoleoylcarnitine
A long-chain acylcarnitine
GC34193 2-(4-Methoxyphenyl)acetic acid (4-Methoxyphenylacetic acid)
对甲氧基苯乙酸,4-Methoxyphenylacetic acid
2-(4-Methoxyphenyl)acetic acid (p-Anisylacetic acid, 4-Methoxyphenylacetic acid) is a 4-O-Methylated catecholamine metabolite found in normal human urine, cerebrospinal fluid and brain tissue.
GC34181 Tauroursodeoxycholate (TUDCA)
牛磺熊去氧胆酸; Tauroursodeoxycholic acid; TUDCA; UR 906
牛磺酸脱氧胆酸盐(TUDCA)是包括肝细胞在内的多种细胞的细胞保护剂,也是癌症细胞凋亡的诱导剂。
GC34179 2-Methoxybenzoic acid (NSC 3778)
邻甲氧基苯甲酸,NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether
2-Methoxybenzoic acid (o-Anisic acid) is a flavouring agent.
GC34134 Glycocholic acid
甘氨胆酸
Glycocholic acid是一种参与脂肪乳化的结晶胆汁酸，是胆酸与甘氨酸的结合物，它以钠盐的形式存在于哺乳动物的胆汁中。