3-hydroxy Decanoic acid is a hydroxy fatty acid and the predominant monomer in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by P. putida CA-3.1 It is present in LPS from the H. pylori strain SS1 and in the lipid A component of clinical isolates of P. aeruginosa isolated from patients with cystic fibrosis but not the environment or patients with other conditions.2,3 3-hydroxy Decanoic acid inhibits mitotic progression of O. virens pollens via impairment of plasma membrane function.4 It also induces a reversible shape change of the membrane crenation in human erythrocytes. [Matreya, LLC. Catalog No. 1727]
1.O'Connor, S., Szwej, E., Nikodinovic-Runic, J., et al.The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoateBiomaterials34(11)2710-2718(2013) 2.Leker, K., Lozano-Pope, I., Bandyopadhyay, K., et al.Comparison of lipopolysaccharides composition of two different strains of Helicobacter pyloriBMC Microbiol.17(1)226(2017) 3.Ernst, R.K., Moskowitz, S.M., Emerson, J.C., et al.Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosisJ. Infect. Dis.196(7)1088-1092(2007) 4.Kanaho, Y., Sato, T., Fuji, T., et al.Shape-transforming action of myrmicacin (3-hydroxydecanoic acid) and some related compounds on the membrane of intact human erythrocytesChem. Pharm. Bull. (Tokyo)29(10)3063-3066(1981)