5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine .1 It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.2
1.Tezuka, M., Chiba, Y., Okada, S., et al.Enhancement of antitumor activity of 5-fluorouracil by ribothymidineJ. Pharmacobiodyn.9(8)683-687(1986) 2.Magni, G., Fioretti, E., Ipata, P.L., et al.Bakers' yeast uridine nucleosidase. Purification, composition, and physical and enzymatic propertiesJ. Biol. Chem.250(1)9-13(1975)
















