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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for  Endogenous Metabolite

  1. Cat.No. 产品名称 Information
  2. GC34123 Deoxycytidine triphosphate (dCTP)

    脱氧胞苷三磷酸; dCTP; 2′-Deoxycytidine-5′-triphosphate

     脱氧胞苷三磷酸 (dCTP) (dCTP) 是一种核苷三磷酸，可用于 DNA 合成。
  3. GC34113 N-(5-Aminopentyl)acetamide (Monoacetylcadaverine)

    N-(5-氨基戊基)乙酰胺,Monoacetylcadaverine

     N-(5-Aminopentyl)acetamide (Monoacetylcadaverine, N-Acetylcadaverine) is the acetylated form of the polyamine cadaverine, which is a foul-smelling diamine compound.
  4. GC34092 Glycochenodeoxycholic acid (Chenodeoxycholylglycine)

    甘氨鹅脱氧胆酸; Chenodeoxycholylglycine

     A quantitative analytical standard guaranteed to meet MaxSpec? identity, purity, stability, and concentration specifications
  5. GC34052 Fosfructose (Diphosphofructose)

    二磷酸果糖; Diphosphofructose; Esafosfan; FDP

     Fosfructose (Diphosphofructose) (Diphosphofructose;Esafosfan;FDP) 是一种具有细胞保护作用的天然磷酸糖，可用于治疗心血管缺血、镰状细胞性贫血和哮喘。
  6. GC34040 Fosfructose trisodium (Diphosphofructose (trisodium))

    D-果糖-1,6-二磷酸三钠盐,Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium

     D-Fructose-1,6-diphosphate trisodium salt octahydrate (FBP trisodium salt octahydrate), a common metabolic sugar, is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway.
  7. GC34021 Vitamin K4 (acetomenaphthone)

    维生素K4; acetomenaphthone

     A synthetic form of vitamin K
  8. GC34016 11beta-Hydroxyprogesterone (11β-Hydroxyprogesterone)

    11β-羟孕酮; 11β-Hydroxyprogesterone

     A metabolite of progesterone
  9. GC33995 DL-3-Phenyllactic acid

    DL-Β-苯乳酸

     DL-3-Phenyllacticacid是一种广谱抗菌化合物。
  10. GC33991 Hydroxyphenyllactic acid

    3-(4-羟基苯基)乳酸

     Hydroxyphenyllactic acid是一种酪氨酸代谢物。
  11. GC33976 4',7-Dimethoxyisoflavone (Dimethoxydaidzein)

    4',7-二甲氧基异黄酮; Dimethoxydaidzein

     4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
  12. GC33930 Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid)

    对羟基苯丙酸; 3-(4-Hydroxyphenyl)propionic acid

     Phloretic acid (Desaminotyrosine, Hydro-p-coumaric acid, Phloretate, 3-(4-Hydroxyphenyl)propanoic acid) is a naturally occurring phenolic compound which can be produced by the hydrogenation of p-coumaric acid or synthesized from phloretin, a by-product of apple tree leaves.
  13. GC33901 Pentanoic acid Pentanoicacid是一种短链脂肪酸，是细菌代谢产物，与过敏性皮肤病有关系。Pentanoicacid能够激活ROCK信号通路。
  14. GC33860 25-Hydroxycholesterol

    25-羟基胆固醇

     25-羟基胆固醇是胆固醇代谢生成的一种侧链氧甾醇，由巨噬细胞响应 Toll 样受体(TLR)激活分泌。
  15. GC33855 DL-α-Tocopherol acetate (Vitamin E acetate)

    生育酚乙酸酯; Vitamin E acetate

     DL-α-Tocopherol acetate (DL-Alpha-tocopherol acetate , Vitamin E acetate), a vitamin E derivative, is used as a vitamin E supplement in poultry feeds.
  16. GC33846 Xanthine

    黄嘌呤

     Xanthine是一种天然存在的嘌呤碱基，广泛存在于茶叶和可可等植物中，也是生物体内嘌呤代谢途径的关键中间体。
  17. GC33839 Cortisone (17-Hydroxy-11-dehydrocorticosterone)

    可的松

     A precursor and metabolite of cortisol
  18. GC33838 Taurocholic Acid sodium hydrate (Sodium taurocholate hydrate)

    牛磺胆酸钠水合物; Sodium taurocholate hydrate; N-Choloyltaurine sodium salt hydrate

     Taurocholic acid (Sodium taurocholate hydrate), a bile salt formed in the liver, is the product of conjugation of cholic acid with taurine that is involved in the emulsification of lipids. Its sodium salt is the chief ingredient of the bile of carnivorous animals.
  19. GC33830 Uridine triphosphate (UTP)

    三磷酸尿苷; UTP; Uridine 5'-triphosphate

     三磷酸尿苷 (UTP) (UTP;Uridine 5'-triphosphate) 是一种核苷酸，可在正常和疾病状态下调节胰腺在内分泌和外分泌分泌、增殖、通道、转运体和细胞内信号传导方面的功能。
  20. GC33827 Uric acid

    尿酸

     Uric Acid (2,6,8-Trioxypurine, 2,6,8-Trihydroxypurine, 2,6,8-Trioxopurine), a normal component of urine, is a product of the metabolic breakdown of purine nucleotides.
  21. GC33825 Taurochenodeoxycholic acid (12-Deoxycholyltaurine)

    牛磺鹅去氧胆酸; 12-Deoxycholyltaurine

     Taurochenodeoxycholic acid (12-Deoxycholyltaurine)是一种牛磺酸结合胆汁酸。
  22. GC33824 SDMA (Symmetric dimethylarginine)

    对称N,N-二甲基精氨酸,Symmetric dimethylarginine; NG,NG'-Dimethyl-L-arginine

     SDMA (Symmetric dimethylarginine)是精氨酸的甲基化形式，是一氧化氮合酶（NOS）的内源性抑制剂。
  23. GC33819 Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid)

    四氢叶酸; L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid; THFA

     Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid)是维生素B9（叶酸或蝶酰-L-谷氨酸）的衍生物，在甲基四氢叶酸介导的吲哚胺甲基化过程中形成，并对甲基四氢叶酸依赖性甲基转移酶具有抑制作用，Ki值为0.1mM。
  24. GC33818 18-Hydroxycorticosterone

    18-羟基皮质酮

    18-Hydroxycorticosterone是皮质类固醇和皮质酮的衍生物，可能会引起严重的电解质失衡。
  25. GC33817 3,5-Dihydroxybenzoic acid 3,5-Dihydroxybenzoicacid是啤酒，坚果，花生和豆类等食物摄入的潜在生物标记。
  26. GC33815 4-Hydroxyphenylacetic acid

    4-羟基苯乙酸

     A phenolic acid with anti-inflammatory and anti-steatotic activities
  27. GC33814 Glutaric acid

    戊二酸

     Glutaric acid (GA) is an attractive C5 dicarboxylic acid with wide applications in the biochemical industry.
  28. GC33811 Pimelic acid (1,5-Pentanedicarboxylic acid)

    庚二酸,Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid

     Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) originating from fatty acid synthesis pathway is a bona fide precursor of biotin in B. subtilis.
  29. GC33810 2-Methoxyestrone

    2-甲基雌酮

     An active metabolite of estrone
  30. GC33807 Alloepipregnanolone

    别孕烯醇酮

     An Analytical Reference Standard
  31. GC33806 Tricosanoic acid

    二十三烷酸

     A saturated fatty acid
  32. GC33805 Adipic acid

    己二酸

     Adipic acid (Hexanedioic acid) is an important dicarboxylic acid used for the manufacture of nylon and polyurethane plastics.
  33. GC33804 Glycogen

    糖原

     Glycogen (糖原)是一种多糖，在动物和细菌中作为重要的能量储存分子。
  34. GC33803 Pi-Methylimidazoleacetic acid

    Pi-Methylimidazoleaceticacid是一种潜在的神经毒素。
  35. GC33802 N-Acetyl-L-tyrosine

    N-乙酰-L-酪氨酸

     An active metabolite of, and precursor to, L-tyrosine
  36. GC33801 1,5-Anhydrosorbitol

    1,5-酐-D-山梨糖醇

     1,5-anhydro-D-glucitol 是 D-glucitol 的脱水糖。它具有作为人体代谢物的作用，在功能上与D-葡萄糖醇有关，是评价短期血糖控制情况的指标
  37. GC33800 10Z-Nonadecenoic acid

    十九碳烯酸(顺-10)

     10Z-Nonadecenoic acid 是一种具有抗肿瘤活性的长链脂肪酸。也可以抑制 p53 活性
  38. GC33799 Ursocholic acid

    熊果胆酸

     Ursocholic acid是胆酸的7β-羟基差向异构体，具有高亲水性。
  39. GC33798 21-Hydroxypregnenolone 21-Hydroxypregnenolone是皮质酮合成的重要中间体。
  40. GC33797 (3-Carboxypropyl)trimethylammonium chloride

    (3-羧丙基)三甲基氯化铵,γ-Butyrobetaine hydrochloride

     (3-Carboxypropyl)trimethylammonium chloride (γ-Butyrobetaine, γBB hydrochloride) is an intermediary metabolite by gut microbes from dietary L-carnitine in mice.
  41. GC33789 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE)

    1,2-二硬酯酰-SN-甘油-3-磷酰乙醇胺,DSPE

     1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE)是一种磷脂酰乙醇胺（PE）脂质，可用于制备脂质体。
  42. GC33779 Cysteamine (β-Mercaptoethylamine)

    巯基乙胺

     2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.
  43. GC33778 Hippuric acid (2-Benzamidoacetic acid)

    马尿酸,2-Benzamidoacetic acid

     Hippuric acid (2-Benzamidoacetic acid) 是一种口服活性代谢物。
  44. GC33777 Creatine

    肌酸

     Creatine (Methylguanidoacetic acid) is a nitrogenous organic acid that occurs naturally in vertebrates. It facilitates the recycling of adenosine triphosphate (ATP) primarily in muscle and brain tissue.Creatine can inhibits the JAK-STAT1 signal transmission by inhibiting the interaction of IFN-γ receptors with JAK2 in an ATP-independent manner, thereby inhibiting downstream pro-inflammatory gene expression.
  45. GC33773 Elaidic acid

    反油酸

     A trans fatty acid
  46. GC33768 Deoxycholic acid sodium salt (Sodium deoxycholate)

    脱氧胆酸钠; Sodium deoxycholate

     Deoxycholic acid sodium salt (Sodium deoxycholate)是一种胆汁酸，是肠道代谢的副产物，可激活 G 蛋白偶联胆汁酸受体 TGR5。
  47. GC33762 Deoxycholic acid (Cholanoic Acid)

    去氧胆酸; Cholanoic Acid; Desoxycholic acid

     Deoxycholic acid (Cholanoic Acid)是一种胆汁酸，肠道代谢副产物，可以激活G 蛋白偶联胆汁酸受体TGR5。
  48. GC33748 Ethylmalonic acid

    乙基丙二酸

     Ethylmalonicacid是一种非致癌性的潜在有毒物质，与神经性厌食和甲氧基脱羧酶缺乏症有关。
  49. GC33746 Dehydroascorbic acid

    脱氢抗坏血酸

     An oxidized form of ascorbic acid
  50. GC33742 2-Hydroxyphenylacetic acid

    邻羟基苯乙酸

     2-Hydroxyphenylacetic acid (2-Hydroxybenzeneacetate, ortho-Hydroxyphenylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway styrene degradation.
  51. GC33739 3-Methoxytyramine (3-O-methyl Dopamine)

    4-(2-氨基乙基)-2-甲氧基苯酚,3-O-methyl Dopamine

     3-Methoxytyramine (3-O-methyl Dopamine) 是一种众所周知的 3-羟基酪胺/多巴胺的细胞外代谢物，是一种神经调节剂。

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