Phenylacetylglutamine (NSC203800) is a colic microbial metabolite that comes from amino acid fermentation phenylacetylglutamine is a colic microbial metabolite of amino acid fermentation and it comes from the glutamine binding of phenylacetic acid, phenylacetic acid is almost entirely from the microbial conversion of phenylalanine[1].
Phenylacetylglutamine (NSC203800) might be a potential biomarker for ischemic stroke (IS) and unfavorable functional outcomes in patients with IS[2].
References:
[1]. Poesen R, Claes K, et,al. Microbiota-Derived Phenylacetylglutamine Associates with Overall Mortality and Cardiovascular Disease in Patients with CKD. J Am Soc Nephrol. 2016 Nov;27(11):3479-3487. doi: 10.1681/ASN.2015121302. Epub 2016 May 26. PMID: 27230658; PMCID: PMC5084895.
[2]. Yu F, Li X, Feng X, Wei M, Luo Y, Zhao T, Xiao B, Xia J. Phenylacetylglutamine, a Novel Biomarker in Acute Ischemic Stroke. Front Cardiovasc Med. 2021 Dec 23;8:798765. doi: 10.3389/fcvm.2021.798765. PMID: 35004911; PMCID: PMC8733610.