GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC30767 structure
    GC30767Heparan Sulfate
    CAS: 9050-30-0
    纯度: {{1-9}Po-58.0 IU/mg}

    硫酸乙酰肝素 (HS) 是一种复杂的聚阴离子多糖，广泛表达于细胞表面和细胞外基质。

  • GC30775 structure
    GC30775Histamine (Ergamine)
    CAS: 51-45-6
    纯度: >99.00% / >98.00%

    A biogenic amine

  • GC30795 structure
    GC30795D-Galactose (D-(+)-Galactose)
    CAS: 59-23-4
    纯度: >99.00%

    A natural aldohexose

  • GC30806 structure
    GC30806Cyclo(his-pro) (Cyclo(histidyl-proline))
    CAS: 53109-32-3
    纯度: >98.00%

    Cyclo(his-pro) (Cyclo(histidyl-proline))是一种内源性、可透过血脑屏障的环状二肽，来源于促甲状腺激素释放激素（TRH）的分解代谢。

  • GC30842 structure
    GC30842Androsterone (5α-Androstan-3α-ol-17-one)
    CAS: 53-41-8
    纯度: >98.00% / >95.00%

    Androsterone (5α-Androstan-3α-ol-17-one)是睾酮的一种代谢产物，可调节癫痫发作的易感性。

  • GC30872 structure
    GC30872Pipecolic acid
    CAS: 535-75-1

    Pipecolic acid (piperidine-2-carboxylic acid), a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and humans alike.

  • GC31180 structure
    GC31180Royal Jelly acid (Queen Bee Acid)
    CAS: 14113-05-4
    纯度: >98.00%

    An unsaturated fatty acid found in royal jelly

  • GC31186 structure
    GC31186Citicoline sodium salt
    CAS: 33818-15-4
    纯度: >99.50%

    Citicoline sodium salt是胞磷胆碱的水溶性形式，胞磷胆碱是磷脂酰胆碱合成过程中的天然中间体，作为乙酰胆碱和磷脂酰胆碱在大脑中的前体，具有抑制活性氧（ROS）产生和细胞凋亡的生物学功能。

  • GC31210 structure
    GC31210Paraxanthine
    CAS: 611-59-6
    纯度: >98.00%

    An active metabolite of caffeine

  • GC31219 structure
    GC312198-Hydroxyguanosine
    CAS: 3868-31-3
    纯度: >99.50%

    An oxidized nucleoside and a marker of RNA oxidative damage

  • GC31222 structure
    GC312222-Hydroxy-3-methylbutanoic acid
    CAS: 4026-18-0

    2-Hydroxy-3-methylbutanoic acid (3-Methyl-2-hydroxybutyric acid, 2-Hydroxyisopentanoic acid, 2-Oxyisovaleric acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, 3-ketothiolase deficiency, isovaleric acidemia, 3-methylcrotonylglycemia, 3-hydroxy-3-methylglutaric acidemia, multiple carboxylase deficiency, glutaric aciduria, ornithine transcarbamylase deficiency, glyceroluria, tyrosinemia type I, galactosemia, and maple syrup urine disease.

  • GC31223 structure
    GC31223Tyramine
    CAS: 51-67-2
    纯度: >99.50%

    A monoamine and TAAR1 agonist

  • GC31240 structure
    GC31240Stearoylethanolamide
    CAS: 111-57-9
    纯度: >98.00% / >95.00%

    An endocannabinoid

  • GC31241 structure
    GC31241D-Arabitol
    CAS: 488-82-4
    纯度: >95.00%

    A fungal metabolite

  • GC31253 structure
    GC31253Palmitoleic acid
    CAS: 373-49-9
    纯度: >99.00% / >98.00% / >99.50%

    Palmitoleic acid是一种omega-7单不饱和脂肪酸，在澳洲坚果植物中含量很高。

  • GC31282 structure
    GC31282p-Hydroxybenzaldehyde
    CAS: 123-08-0

    p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol), which can be found in the orchids Gastrodia elata, Galeola faberi and vanilla, is a hydroxybenzaldehyde that reacts with NAD+ and H2O to produce 4-hydroxybenzoate, NADH, and 2 protons. p-Hydroxybenzaldehyde at 101.7 μM can significantly reduce the GABA-induced chloride current of GABAA receptors(α1β2γ2S subtype) expressed.

  • GC31290 structure
    GC312903-Indolepropionic acid
    CAS: 830-96-6
    纯度: >99.50%

    A bacterial metabolite with antioxidant and neuroprotective activities

  • GC31307 structure
    GC313074-Methyl-2-oxopentanoic acid
    CAS: 816-66-0
    纯度: >99.00% / >98.00%

    4-Methyl-2-oxopentanoic acid是一种异常代谢物、神经毒素和代谢毒素。4-Methyl-2-oxopentanoic acid通过损害 mTOR 和自噬信号通路，增加内质网应激，促进前脂肪细胞脂质积累和胰岛素抵抗。

  • GC31316 structure
    GC31316H-Phe-Phe-OH
    CAS: 2577-40-4
    纯度: >98.00% / >99.50%

    H-Phe-Phe-OH (Phenylalanyl-phenylalanine, Phe-Phe, L-Phe-L-Phe) is a short peptide diphenylalanine with utility for potential applications in biomaterial chemistry, sensors and bioelectronics.

  • GC31328 structure
    GC31328Thyroxine sulfate (T4 Sulfate)
    CAS: 77074-49-8
    纯度: >99.50%

    硫酸甲状腺素 (T4 Sulfate) 是一种甲状腺激素代谢物。

  • GC31337 structure
    GC31337Spermidine (N-(4-Aminobutyl)-1,3-diaminopropane)
    CAS: 124-20-9
    纯度: >99.00%

    Spermidine是一种天然多胺，可通过与DNA/RNA结合并稳定其结构、发挥抗氧化活性、调节酶功能以及参与翻译调控来维持细胞稳态。

  • GC31352 structure
    GC31352Sucrose (D-(+)-Saccharose)
    CAS: 57-50-1
    纯度: >98.00%

    Sucrose (D-(+)-Saccharose), a common sugar produced naturally in plants, is a disaccharide, a molecule composed of two monosaccharides:glucose and fructose.

  • GC31353 structure
    GC31353Glutathione oxidized (L-Glutathione oxidized)
    CAS: 27025-41-8
    纯度: >98.50% / >99.00%

    Glutathione oxidized (L-Glutathione oxidized)，是抗氧化剂L-谷胱甘肽的氧化形式，作为一种信号分子，可触发抗氧化基因的激活。

  • GC31397 structure
    GC31397Guanidine hydrochloride (Guanidinium chloride)
    CAS: 50-01-1

    Guanidine盐酸盐是蛋白代谢产物和蛋白变性剂，由鸟嘌呤氧化形成。