Endogenous Metabolite
Endogenous Metabolite(内源性代谢物)
Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Endogenous Metabolite 相关产品(1712)
- GC30715Guanosine 5'-diphosphateCAS: 146-91-8纯度: >98.00% / >95.00%
Guanosine 5'-diphosphate作为一种关键的核苷二磷酸，通过G蛋白信号转导作为细胞内信号级联反应的调节剂。
- GC30716Levulinic acid (4-Oxovaleric acid)CAS: 123-76-2纯度: >98.00%
Levulinic acid (4-oxopentanoic acid, β-Acetylpropionic acid, 3-Acetopropionic acid, γ-ketovaleric acid) is used as a precursor for pharmaceuticals, plasticizers, and various other additives.
- GC307182-Amino-1-phenylethanolCAS: 7568-93-6纯度: >97.00%
2-Amino-1-phenylethanol (2-APE) is a noradrenaline analogue.
- GC307193-Amino-4-methylpentanoic acidCAS: 5699-54-7纯度: >98.00%
3-Amino-4-methylpentanoic acid (beta-Leucine, DL-Homovaline, DL-beta-leucine, beta-Aminoisocaproic acid) is a human metabolite.
- GC307202-NaphtholCAS: 135-19-3纯度: >99.50%
2-Naphthol (2-Hydroxynaphthalene, 2-Naphthalenol, beta-Naphthol, Naphth-2-ol, β-naphthol), a potential antinematodal drug, is a widely used intermediate for the production of dyes and other compounds.
- GC30724trans-Vaccenic acidCAS: 693-72-1纯度: >99.00%
trans-Vaccenic acid是一种单不饱和脂肪酸，是反刍动物来源的脂质中最主要的一种反式异构体。
- GC30726Eicosadienoic acidCAS: 2091-39-6纯度: >98.00%
Eicosadienoic acid能够抑制小鼠5'-单磷酸肌苷脱氢酶（IMPDH）的活性，并且与IMPDH的结合具有竞争性（K i =3.1μM）。
- GC307293-Hydroxyvaleric acidCAS: 10237-77-1纯度: >98.00%
3-Hydroxyvalericacid是一种五碳酮体。3-Hydroxyvalericacid可以发生回补反应，即可以补充三羧酸循环的中间产物。
- GC30730Monoisobutyl phthalic acidCAS: 30833-53-5纯度: >96.50%
Monoisobutylphthalicacid是一种邻苯二甲酸酯代谢物，存在于人的精液和肽粪中。
- GC30735(S)-Leucic acidCAS: 13748-90-8纯度: >98.00%
Leucic acid ((S)-α-hydroxyisocaproic acid) is a metabolite of the branched chain amino acid known as leucine, which plays a significant role in the synthesis of muscle protein.
- GC30744Norepinephrine (Adrenor)CAS: 51-41-2纯度: >98.00%
(-)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively.
- GC30745L-PalmitoylcarnitineCAS: 2364-67-2纯度: >98.00% / >97.00%
L-Palmitoylcarnitine 是一种重要的内源性脂肪酸代谢物，可同时提高离子通道对 ATP 的敏感性，IC 50 值在 30.3 ± 5.5μM和62.0 ± 2.7之间。
- GC307491,3-Dimethyluric acidCAS: 944-73-0纯度: >98.00%
1,3-二甲基尿酸（1,3-Dimethyluric acid）是一种氧嘌呤，它是 7,9-二氢-1H-嘌呤-2,6,8(3H)-三酮，在 N-1 和 N-3 被甲基取代。是人体茶碱代谢的产物。1,3-二甲基尿酸是尿路结石中的嘌呤成分之一。
- GC30753Ureidopropionic acidCAS: 462-88-4纯度: >98.00%
Ureidopropionic acid is an intermediate in the metabolism of uracil.
- GC30765Docosahexaenoic Acid (DHA)CAS: 6217-54-5纯度: >98.00% / >99.50% / >95.00%
二十二碳六烯酸 (DHA) 是一种长链多不饱和脂肪酸，对婴儿和成人均有活性。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC30715 | Guanosine 5'-diphosphate | 146-91-8 | >98.00% / >95.00% | |
Guanosine 5'-diphosphate作为一种关键的核苷二磷酸，通过G蛋白信号转导作为细胞内信号级联反应的调节剂。 | ||||
| GC30716 | Levulinic acid (4-Oxovaleric acid) | 123-76-2 | >98.00% | |
Levulinic acid (4-oxopentanoic acid, β-Acetylpropionic acid, 3-Acetopropionic acid, γ-ketovaleric acid) is used as a precursor for pharmaceuticals, plasticizers, and various other additives. | ||||
| GC30718 | 2-Amino-1-phenylethanol | 7568-93-6 | >97.00% | |
2-Amino-1-phenylethanol (2-APE) is a noradrenaline analogue. | ||||
| GC30719 | 3-Amino-4-methylpentanoic acid | 5699-54-7 | >98.00% | |
3-Amino-4-methylpentanoic acid (beta-Leucine, DL-Homovaline, DL-beta-leucine, beta-Aminoisocaproic acid) is a human metabolite. | ||||
| GC30720 | 2-Naphthol | 135-19-3 | >99.50% | |
2-Naphthol (2-Hydroxynaphthalene, 2-Naphthalenol, beta-Naphthol, Naphth-2-ol, β-naphthol), a potential antinematodal drug, is a widely used intermediate for the production of dyes and other compounds. | ||||
| GC30722 | Anserine | 584-85-0 | - | |
Anserine (β-alanyl-N-methylhistidine) is a dipeptide containing β-alanine and 1-methylhistidine. It is normally absent from human tissues and body fluids, and its appearance there is an artifact of diet and serum carnosinase deficiency. | ||||
| GC30723 | Ubiquinone-1 | 727-81-1 | >99.00% | |
Ubiquinone-1是辅酶Q合成过程中的中间体。 | ||||
| GC30724 | trans-Vaccenic acid | 693-72-1 | >99.00% | |
trans-Vaccenic acid是一种单不饱和脂肪酸，是反刍动物来源的脂质中最主要的一种反式异构体。 | ||||
| GC30726 | Eicosadienoic acid | 2091-39-6 | >98.00% | |
Eicosadienoic acid能够抑制小鼠5'-单磷酸肌苷脱氢酶（IMPDH）的活性，并且与IMPDH的结合具有竞争性（K i =3.1μM）。 | ||||
| GC30727 | Beta-Cortol | 667-65-2 | >98.00% | |
An endogenous metabolite of cortisol | ||||
| GC30728 | Isobutyryl-L-carnitine | 25518-49-4 | - | |
An acylcarnitine | ||||
| GC30729 | 3-Hydroxyvaleric acid | 10237-77-1 | >98.00% | |
3-Hydroxyvalericacid是一种五碳酮体。3-Hydroxyvalericacid可以发生回补反应，即可以补充三羧酸循环的中间产物。 | ||||
| GC30730 | Monoisobutyl phthalic acid | 30833-53-5 | >96.50% | |
Monoisobutylphthalicacid是一种邻苯二甲酸酯代谢物，存在于人的精液和肽粪中。 | ||||
| GC30732 | Guanosine (DL-Guanosine) | 118-00-3 | >98.00% | |
A purine nucleoside | ||||
| GC30735 | (S)-Leucic acid | 13748-90-8 | >98.00% | |
Leucic acid ((S)-α-hydroxyisocaproic acid) is a metabolite of the branched chain amino acid known as leucine, which plays a significant role in the synthesis of muscle protein. | ||||
| GC30742 | 1,3-Diaminopropane | 109-76-2 | >98.00% | |
1,3-Diaminopropane是一种三碳二胺，是鸟氨酸脱羧酶抑制剂。 | ||||
| GC30744 | Norepinephrine (Adrenor) | 51-41-2 | >98.00% | |
(-)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline) is a natural neurotransmitter and hormone. It is an agonist of adrenergic receptors with Ki values of 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively. | ||||
| GC30745 | L-Palmitoylcarnitine | 2364-67-2 | >98.00% / >97.00% | |
L-Palmitoylcarnitine 是一种重要的内源性脂肪酸代谢物，可同时提高离子通道对 ATP 的敏感性，IC 50 值在 30.3 ± 5.5μM和62.0 ± 2.7之间。 | ||||
| GC30749 | 1,3-Dimethyluric acid | 944-73-0 | >98.00% | |
1,3-二甲基尿酸（1,3-Dimethyluric acid）是一种氧嘌呤，它是 7,9-二氢-1H-嘌呤-2,6,8(3H)-三酮，在 N-1 和 N-3 被甲基取代。是人体茶碱代谢的产物。1,3-二甲基尿酸是尿路结石中的嘌呤成分之一。 | ||||
| GC30753 | Ureidopropionic acid | 462-88-4 | >98.00% | |
Ureidopropionic acid is an intermediate in the metabolism of uracil. | ||||
| GC30757 | DL-Homocysteine thiolactone hydrochloride | 6038-19-3 | - | |
A derivative of DL-homocysteine | ||||
| GC30758 | m-Coumaric acid | 588-30-7 | - | |
m-Coumaricacid是来自咖啡酸的多酚代谢物，由肠道微生物群形成，体液中的量是饮食依赖性的。 | ||||
| GC30760 | Pentadecanoic acid | 1002-84-2 | >98.00% | |
A saturated fatty acid | ||||
| GC30765 | Docosahexaenoic Acid (DHA) | 6217-54-5 | >98.00% / >99.50% / >95.00% | |
二十二碳六烯酸 (DHA) 是一种长链多不饱和脂肪酸，对婴儿和成人均有活性。 | ||||