DL-Homocysteine thiolactone is a derivative of DL-homocysteine .1 It inhibits the growth of B. campestris, L. sativa, and E. utilis roots when used at a concentration of 50 ?M.2 DL-Homocysteine thiolactone (10 ?M) decreases the maximum rate of left ventricular developed pressure, systolic left ventricular pressure, and coronary flow in isolated rat hearts.3 It induces arteriosclerotic plaque formation in rabbits when administered at a dose of 30 mg/kg for eight weeks.1 DL-Homocysteine thiolactone has also been used as a precursor in the synthesis of thiolactone-containing monomers for use in polymer-based formaldehyde-scavenging coatings.4
1.McCully, K.S., and Wilson, R.B.Homocysteine theory of arteriosclerosisAtherosclerosis22(2)215-227(1975) 2.Inamori, Y., Muro, C., Toyoda, M., et al.Root-growth inhibition by ??-homocysteine thiolactone and its related compoundsBiosci. Biotech. Biochem.59(3)523-525(1995) 3.Zivkovic, V., Jakovljevic, V., Pechanova, O., et al.Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: The role of different gasotransmittersBiomed. Res. Int.318471(2013) 4.Resetco, C., Frank, D., Diki?, T., et al.Thiolactone-based polymers for formaldehyde scavenging coatingsEur. Polym. J.82166-174(2016)