GlpBio

PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR Signaling(PI3K/Akt/mTOR 信号传导)

研究方向

PI3K/Akt/mTOR Signaling 相关产品(648)

  • GC19328 structure
    GC19328SF2523
    CAS: 1174428-47-7

    A dual inhibitor of PI3K and BRD4

  • GC19355 structure
    GC19355Umbralisib
    CAS: 1532533-67-7
    纯度: >98.50%

    A PI3K p110δ inhibitor

  • GC19390 structure
    GC19390YU238259
    CAS: 1943733-16-1
    纯度: >99.50%

    An inhibitor of homology-dependent DNA repair

  • GC19411 structure
    GC19411IITZ-01
    CAS: 1807988-47-1
    纯度: >99.00%

    IITZ-01 是一种有效的溶酶体自噬抑制剂，具有单剂抗肿瘤活性，对 PI3Kγ 的 IC50 为 2.62 μM。

  • GC19471 structure
    GC19471Leniolisib
    CAS: 1354690-24-6
    纯度: >99.00%

    An inhibitor of PI3Kδ

  • GC19484 structure
    GC19484BAY1125976
    CAS: 1402608-02-9
    纯度: >99.50%

    An allosteric inhibitor of Akt1/2

  • GC19540 structure
    GC19540α-Linolenic Acid
    CAS: 463-40-1
    纯度: >98.00% / >99.00% / >99.50%

    An essential ω-3 polyunsaturated fatty acid

  • GC19843 structure
    GC19843Nimbolide
    CAS: 25990-37-8
    纯度: >98.00%

    An anticancer phytochemical

  • GC19921 structure
    GC19921Phenylarsine Oxide
    CAS: 637-03-6
    纯度: >98.00%

    An organoarsenic compound

  • GC25626 structure
    GC25626MELK-8a Dihydrochloride
    CAS: 1922153-17-0 (free base)

    MELK-8a Dihydrochloride is a novel inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 of 2 nM.

  • GC25638 structure
    GC25638Miransertib (ARQ 092) HCl
    CAS: 1313883-00-9

    Miransertib (ARQ 092) HCl is a novel, orally bioavailable and selective AKT pathway inhibitor exhibiting a manageable safety profile among patients with advanced solid tumors.

  • GC25648 structure
    GC25648MOTS-c
    CAS: 1627580-64-6

    MOTS-c是一种线粒体衍生的具有代谢调节功能的多肽。

  • GC25913 structure
    GC25913Selective PI3Kδ Inhibitor 1 (compound 7n)
    CAS: 2088525-31-7

    Selective PI3Kδ Inhibitor 1 (compound 7n) is an inhibitor of PI3Kδ with an IC50 of 0.9 nM and >1000-fold selectivity against other class I PI3K isoforms [PI3K α/γ/β=3670/1460/21300 nM].

  • GC26044 structure
    GC26044VPS34 inhibitor 1 (Compound 19)
    CAS: 1383716-46-8

    VPS34 inhibitor 1 (Compound 19, PIK-III analogue) is a potent and selective inhibitor of VPS34 with an IC50 of 15 nM.

  • GC26049 structure
    GC26049WAY-119064
    CAS: 1198098-03-1

    WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.

  • GC30056 structure
    GC30056Danthron (Dantron)
    CAS: 117-10-2
    纯度: >98.50%

    Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.

  • GC30156 structure
    GC30156Brevianamide F (Cyclo(L-Pro-L-Trp))
    CAS: 38136-70-8
    纯度: >99.00%

    An alkaloid with diverse biological activities

  • GC30229 structure
    GC30229Cbz-B3A
    CAS: 1884710-81-9

    Cbz-B3A是mTORC1转导的有效选择性抑制剂，与泛素1、2、4结合，Cbz-B3A还能抑制eIF4E结合蛋白的磷酸化。

  • GC30582 structure
    GC30582Crosstide
    CAS: 171783-05-4

    A peptide substrate for Akt

  • GC30770 structure
    GC30770LM22B-10
    CAS: 342777-54-2
    纯度: >98.00%

    An activator of TrkB and TrkC

  • GC30777 structure
    GC30777PI4KIIIbeta-IN-10
    CAS: 1881233-39-1
    纯度: >99.50%

    PI4KIIIbeta-IN-10是一种有效的PI4KIIIβ抑制剂，IC50为3.6nM。

  • GC30884 structure
    GC30884LX2343
    CAS: 333745-53-2
    纯度: >99.50%

    An inhibitor of BACE1 and PI3K

  • GC31348 structure
    GC313487-Methoxyisoflavone
    CAS: 1621-56-3
    纯度: >99.50%

    A synthetic isoflavone

  • GC31361 structure
    GC31361MK-3903
    CAS: 1219737-12-8
    纯度: >98.00%

    An AMPK activator