GlpBio

GSK-3

GSK-3(糖原合成酶激酶3)

GSK3 (glycogen synthase kinase-3) is a serine/threonine protein kinase which contributes to cell survival, diabetes, insulin resistance and Alzheimer's diseases.

GSK-3 相关产品(69)

  • GC10463 structure
    GC10463SB 216763
    CAS: 280744-09-4
    纯度: >99.00%

    SB 216763是一种强效、选择性且ATP竞争性的GSK-3抑制剂，显著作用于GSK-3α和GSK-3β，其IC50仅为34.3 nM。

  • GC12176 structure
    GC12176CHIR-98014
    CAS: 252935-94-7
    纯度: >98.00%

    CHIR-98014是一种具细胞渗透性的GSK-3α和GSK-3β的强效抑制剂，IC 50 值分别为0.65nM和0.58nM。

  • GC13028 structure
    GC13028SB 415286
    CAS: 264218-23-7
    纯度: >99.50%

    A selective inhibitor of GSK-3

  • GC15425 structure
    GC15425AR-A014418
    CAS: 487021-52-3
    纯度: >99.00%

    A selective inhibitor of GSK3β

  • GC16702 structure
    GC16702CHIR-99021 (CT99021)
    CAS: 252917-06-9
    纯度: >99.00% / >98.00%

    CHIR-99021是最常用的GSK-3β抑制剂，被认为是标准的小分子Wnt激动剂。

  • GC17153 structure
    GC17153CHIR-99021 (CT99021) HCl
    CAS: 1797989-42-4
    纯度: >99.50%

    A selective GSK3 inhibitor

  • GC17187 structure
    GC17187LY2090314
    CAS: 603288-22-8
    纯度: >99.00%

    A potent and selective inhibitor of GSK3

  • GC10336 structure
    GC10336A 1070722
    CAS: 1384424-80-9
    纯度: >99.00%

    A GSK3β inhibitor

  • GC10752 structure
    GC10752Bikinin
    CAS: 188011-69-0
    纯度: >99.50%

    Bikinin是一种具有ATP竞争性的非甾体类植物GSK-3（糖原合酶激酶3）/Shaggy-like激酶抑制剂。

  • GC12661 structure
    GC12661Indirubin-3'-oxime
    CAS: 160807-49-8
    纯度: >99.00%

    Inhibitor of GSK3β and cyclin-dependent kinases

  • GC13176 structure
    GC13176CP21R7
    CAS: 125314-13-8
    纯度: >99.50%

    A GSK3β inhibitor used to differentiate stem cells

  • GC14182 structure
    GC14182Kenpaullone
    CAS: 142273-20-9
    纯度: >98.00%

    A inhibitor of cyclin-dependent kinase and GSK3β

  • GC14233 structure
    GC14233BIO-acetoxime
    CAS: 667463-85-6
    纯度: >98.00%

    A potent, selective inhibitor of GSK3α/β

  • GC14465 structure
    GC14465Tideglusib
    CAS: 865854-05-3
    纯度: >99.50%

    Tideglusib是一种强效、选择性且不可逆的非ATP竞争性糖原合成酶激酶-3（GSK-3）抑制剂，对GSK-3β WT 和GSK-3β C199A 的IC 50 分别为5nM和60nM。

  • GC14736 structure
    GC14736AZD2858
    CAS: 486424-20-8
    纯度: >99.00%

    A GSK3β inhibitor

  • GC15642 structure
    GC15642CHIR 99021 trihydrochloride
    CAS: 1782235-14-6
    纯度: >98.00%

    A selective GSK3 inhibitor

  • GC15841 structure
    GC15841Alsterpaullone
    CAS: 237430-03-4
    纯度: >98.00%

    A dual CDK and GSK3 inhibitor

  • GC16187 structure
    GC16187GSK-3β Inhibitor II
    CAS: 478482-75-6

    An inhibitor of GSK3β signaling

  • GC16584 structure
    GC16584TCS 21311
    CAS: 1260181-14-3
    纯度: >95.00%

    A JAK3 inhibitor

  • GC16617 structure
    GC16617IM-12
    CAS: 1129669-05-1
    纯度: >98.00%

    A GSK3β inhibitor

  • GC17690 structure
    GC17690Cromolyn sodium
    CAS: 15826-37-6
    纯度: >99.00%

    A mast cell stabilizer

  • GC18810 structure
    GC18810GSK3β Inhibitor XI
    CAS: 626604-39-5

    A potent inhibitor of GSK3β

  • GC26049 structure
    GC26049WAY-119064
    CAS: 1198098-03-1

    WAY-119064 is a potent glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 value of 80.5 nM.

  • GC35162 structure
    GC351625-Iodo-indirubin-3'-monoxime
    CAS: 331467-03-9
    纯度: >99.50%

    5-Iodo-indirubin-3'-monoxime 是一种有效的 GSK-3β，CDK5/P25 和 CDK1/cyclin B 抑制剂，与 ATP 竞争性地结合酶的催化位点，IC50 值分别为 9，20 和 25 nM。