GlpBio

PIKfyve

PIKfyve(含FYVE指磷酸肌醇激酶)

PIKfyve (1-phosphatidylinositol 3-phosphate 5-kinase) catalyzes the production of PtdIns5P and PtdIns(3,5)biphosphate from the phosphorylation o f D-5 position in PtdIns and phosphatidylinositol-3-phosphate. It is involved in endosome carrier vesicle biogenesis in early endosomes and endomembrane homeostasis.

PIKfyve 相关产品(6)

  • GC10982 structure
    GC10982YM201636
    CAS: 371942-69-7
    纯度: >98.00%

    Inhibitor of PIKfyve

  • GC31661 structure
    GC31661APY0201
    CAS: 1232221-74-7
    纯度: >98.00%

    An inhibitor of PIKFYVE

  • GC66013 structure
    GC66013MOMIPP
    CAS: 1363421-46-8
    纯度: >98.00%

    MOMIPP，一种巨胞饮作用的诱导剂，是一种 PIKfyve 抑制剂。MOMIPP 可穿过血脑屏障 (BBB)。

  • GC69711 structure
    GC69711PIKfyve-IN-1
    CAS: 2857982-26-2

    PIKfyve-IN-1 是一种高效且具有细胞活性的化学探针，可抑制 3 磷酸磷脂酰肌醇 5-激酶 (PIKfyve)，IC50 值为 6.9 nM。PIKfyve-IN-1 可用于病毒学中 PIKfyve 的研究。

  • GC73606 structure
    GC73606PIK5-12d
    纯度: >99.00%

    PIK5-12d是PROTAC PIKfyve降降剂（DC50: 1.48 nM）。

  • GC74025 structure
    GC74025PIKfyve-IN-3
    纯度: >99.00%

    PIKfyve-IN-3（化合物L22）与PIKfyve激酶具有显著的相互作用，Kd值为0.47nM。