Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC13959 Adarotene
(2E)-3-(4'-羟基-3'-金刚烷-1-基[1,1'-联苯]-4-基)-2-丙烯酸,ST 1926;ST-1926;ST1926
An atypical retinoid
GC12791 3,3'-Diindolylmethane
3,3'-二吲哚甲烷,diindolylmethane, 3,3'-Methylenediindole,DIM,Arundine,HB236
A phytochemical with antiradiation and chemopreventative effects
GC17557 17 alpha-propionate
克拉司酮,17α-propionate; CB-03-01
A peripherally selective androgen receptor antagonist
GC15373 (E)-2-Decenoic acid
反式-2-癸烯酸,trans-2-Decenoic acid
An unsaturated fatty acid found in royal jelly
GC15382 Isotretinoin
异维A酸; 13-cis-Retinoic acid
A retinoid
GC16649 TAK-700 (Orteronel) A non-steroidal inhibitor of the 17,20-lyase activity of CYP17A1
GC16223 Captopril
卡托普利; SQ 14225
Captopril是一种具有口服活性的血管紧张素转化酶（ACE）抑制剂，IC₅₀值为0.025μM。
GC12385 MDV3100 (Enzalutamide)
恩杂鲁胺; MDV3100
MDV3100(enzalutamide) 是第二代 AR 拮抗剂，在 LNCaP 前列腺细胞中的 IC50 为 36nM。
GN10213 Sinomenine Hydrochloride
盐酸青藤碱; Cucoline hydrochloride
Sinomenine Hydrochloride是NF-κB活化的抑制剂。
GN10268 Triptophenolide
雷酚内酯; Hypolide; (+)-Triptophenolide
A diterpenoid with antiandrogenic activity
GN10024 Saikosaponin A
柴胡皂苷 A
A triterpenoid saponin with diverse biological activities
GN10457 Oleuropein
橄榄苦苷
Oleuropein是橄榄树中的主要酚类化合物，具有强效的抗氧化和抗炎特性。
GN10135 Sec-O-Glucosylhamaudol
亥茅酚苷
Sec-O-Glucosylhamaudol 是一种从前胡中提取的天然化合物，可降低 μ-阿片受体水平，具有镇痛作用。
GN10301 Magnolol
厚朴酚
A CB₂ receptor agonist
GN10142 Lupeol
羽扇豆醇; Clerodol; Monogynol B; Fagarasterol
A dietary triterpene with anti-inflammatory and anticancer activity
GP10088 Luteinizing hormone releasing hormone human acetate salt (LHRH)
醋酸戈那瑞林
MMP-2 和 MMP-9 的激活剂，选择性
GP10024 Growth Hormone (1-43), human
H2N-Phe-Pro-Thr-Ile-Pro-Leu-Ser-Arg-Leu-Phe-Asp-Asn-Ala-Met-Leu-Arg-Ala-His-Arg-Leu-His-Gln-Leu-Ala-Phe-Asp-Thr-Tyr-Gln-Glu-Phe-Glu-Glu-Ala-Tyr-Ile-Pro-Lys-Glu-Gln-Lys-Tyr-Ser-OH
Human Growth Hormone (1-43) peptide
GP10131 Peptide YY(3-36), PYY, human
人多肽YY(3-36),H2N-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
Peptide YY(3-36), PYY, human 是一种内源性食欲抑制肽。
GP10106 Parathyroid Hormone (1-34), bovine
牛甲状旁腺激活素-(1-34),H2N-Ala-Val-Ser-Glu-Ile-Gln-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH
甲状旁腺激素 (1-34), bovine 是一种有效的甲状旁腺激素 (PTH) 受体激动剂。
GP10014 parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]
H2N-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH

Enhancer of blood calcium level
GP10120 Angiotensin 1/2 + A (2 - 8)
H2N-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Vasoconstrictor
GP10012 Angiotensin 1/2 (1-8) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide

Vasoconstrictor
GP10144 Angiotensin 1/2 (1-7) amide
H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide

Vasoconstrictor
GP10045 Angiotensin 1/2 (2-7)
H2N-Arg-Val-Tyr-Ile-His-Pro-OH

Vasoconstrictor
GP10079 Angiotensin 1/2 (5-7)
H2N-Ile-His-Pro-OH

Vasoconstrictor
GP10067 Angiotensin 1/2 (1-6)
H2N-Asp-Arg-Val-Tyr-Ile-His-OH

血管紧张素 I/II 1-6 含有氨基酸 1-6，由血管紧张素 I/II 肽转化而来。
GP10074 Angiotensin 1/2 (1-5)
H2N-Asp-Arg-Val-Tyr-Ile-OH

血管紧张素 I/II 1-5 是一种含有氨基酸 1-5 的肽，由血管紧张素 I/II 转化而来。
GP10112 TRH Precursor Peptide
H2N-Lys-Arg-Gln-His-Pro-Gly-Lys-Arg-OH

Thyrotropin Releasing Hormone Precursor Peptide
GP10059 Acetyl Angiotensinogen (1-14), porcine
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH

Angiotensinogen precursor
GP10109 Adrenorphin
H2N-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-amide

Adrenorphin 是一种阿片样物质八肽，作为 μ-阿片样物质受体的有效激动剂，Ki 为 12 nM。
GP10060 a-MSH, amide
Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-amide, α-MSH, amide
a-MSH(α-黑素细胞刺激素)通过G蛋白转运体与黑色素皮质素-1受体结合并激活环磷酸腺苷(cAMP)信号通路,可以合成黑色素。它是内源性神经肽,是促阿皮黑色素皮质素(POMC)的翻译后衍生物。
GP10043 GnRH Associated Peptide (GAP) (1-13), human
H2N-Asp-Ala-Glu-Asn-Leu-Ile-Asp-Ser-Phe-Gln-Glu-Ile-Val-OH

Inhibitor of prolactin secretion
GP10122 Glucagon (19-29), human
H2N-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH

Glucagon (19-29), human 是一种有效的胰岛素分泌抑制剂。
GP10051 Beta-Lipotropin (1-10), porcine
H2N-Glu-Leu-Ala-Gly-Ala-Pro-Pro-Glu-Pro-Ala-OH

Morphine-like substance
GP10025 Angiotensin 1/2 (1-9)
血管紧张素I,H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-OH

血管收缩药
GP10069 Parathyroid hormone (1-34) (human)
Teriparatide Acetate; 醋酸特立帕肽; Human parathyroid hormone-(1-34); hPTH (1-34)
Parathyroid hormone (1-34) (human)是人类甲状旁腺激素（PTH）的N端片段（34个氨基酸），是甲状旁腺激素1（PTH1）受体的激动剂。
GP10066 Melanocyte stimulating hormone release inhibiting factor
Pro-Leu-Gly
A tripeptide with diverse biological activities
GP10031 Leptin (116-130) amide (mouse)
Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser
Leptin (116-130) amide (mouse) 是一种合成的瘦素肽片段。
GP10065 Endomorphin-1
内吗啡肽 1

An endogenous neuropeptide and μ-opioid receptor agonist
GP10087 Angiotensin I (human, mouse, rat)
血管紧张素 1 (人)
Angiotensin I (human, mouse, rat)是一种十肽激素，为血管紧张素II的前体。