GlpBio

DNA Damage/DNA Repair

DNA Damage/DNA Repair(DNA损伤/DNA修复)

研究方向

DNA Damage/DNA Repair 相关产品(1788)

  • GC12054 structure
    GC12054KU-60019
    CAS: 925701-46-8
    纯度: >98.50% / >98.00%

    A potent ATM kinase inhibitor

  • GC12064 structure
    GC12064SB1317
    CAS: 937270-47-8
    纯度: >99.50%

    A multi-kinase inhibitor

  • GC12067 structure
    GC12067P005091
    CAS: 882257-11-6
    纯度: >99.50%

    P005091是一种有效的选择性泛素特异性蛋白酶7 (USP7) 抑制剂，EC50 值为4.2 μM。

  • GC12074 structure
    GC12074BG45
    CAS: 926259-99-6
    纯度: >99.50%

    A selective HDAC3 inhibitor

  • GC12092 structure
    GC12092TMPyP4 tosylate
    CAS: 36951-72-1
    纯度: >98.00% / >95.00%

    TMPyP4 tosylate是一种四链体特异性配体，可以抑制G-四链体与胰岛素样生长因子I（IGF-1）之间的相互作用。

  • GC12106 structure
    GC12106SCR7
    CAS: 1533426-72-0
    纯度: >98.00% / >97.50%

    SCR7是一种DNA连接酶IV的小分子抑制剂 ，通过结合连接酶IV的DNA结合域（DBD）来抑制非同源末端连接（NHEJ）途径 。

  • GC12131 structure
    GC12131L189
    CAS: 64232-83-3
    纯度: >98.00%

    A DNA ligase inhibitor

  • GC12153 structure
    GC12153Zebularine
    CAS: 3690-10-6
    纯度: >99.50%

    Zebularine是一种缺失4-氨基基团的胞苷类似物，作为DNA甲基转移酶抑制剂可抑制DNA甲基化。

  • GC12181 structure
    GC12181TBB
    CAS: 17374-26-4
    纯度: >99.00% / >99.50% / >98.00%

    TBB是一种细胞可渗透的ATP竞争性CK2抑制剂，对大鼠肝脏CK2的IC 50 为0.15μM。

  • GC12193 structure
    GC121936-Thio-dG
    CAS: 789-61-7
    纯度: >98.00%

    A purine nucleoside analog

  • GC12201 structure
    GC12201HI TOPK 032
    CAS: 487020-03-1
    纯度: >99.00%

    An inhibitor of TOPK, Chk1, and MEK1 kinases

  • GC12266 structure
    GC12266Didox
    CAS: 69839-83-4
    纯度: >98.00%

    Antioxidant and ribonucleotide reductase inhibitor

  • GC12304 structure
    GC12304OTS514
    CAS: 1338540-63-8
    纯度: >98.00%

    A TOPK inhibitor

  • GC12334 structure
    GC12334HNHA
    CAS: 926908-04-5

    HDAC inhibitor

  • GC12348 structure
    GC12348Ro 3306
    CAS: 872573-93-8
    纯度: >98.00%

    Ro 3306是一种ATP竞争性抑制剂，主要靶向CDK1/cyclin B1（K i 值为35nmol/L）和CDK1/cyclin A复合物（K i 值为110nmol/L）。

  • GC12350 structure
    GC12350T-705 (Favipiravir)
    CAS: 259793-96-9
    纯度: >99.50%

    T-705 (Favipiravir)是一种广谱抗病毒药物。T-705通过选择性抑制RNA病毒的RNA依赖性RNA聚合酶（RdRp），发挥抗病毒作用。

  • GC12353 structure
    GC12353Mitomycin C
    CAS: 50-07-7
    纯度: >98.00%

    Mitomycin C是一种抗生素，从链霉菌（Streptomyces Caespitosus）或淡紫色链霉菌（Streptomyces Lavendulae）中分离出来。

  • GC12367 structure
    GC12367CM-272
    CAS: 1846570-31-7
    纯度: >98.00%

    An inhibitor of G9a, GLP, and DNA methyltransferases

  • GC12423 structure
    GC12423Mycophenolate mofetil hydrochloride
    CAS: 116680-01-4

    A prodrug form of mycophenolic acid

  • GC12425 structure
    GC12425CDK inhibitor II
    CAS: 1269815-17-9
    纯度: >98.50%

    CDK inhibitor II 是一种有效且特异性的 CDK9 抑制剂，IC50 <8 nM，取自参考文献 1，实施例 4。

  • GC12438 structure
    GC12438AZD-5438
    CAS: 602306-29-6
    纯度: >99.50%

    A potent inhibitor of CDKs

  • GC12475 structure
    GC12475NSC 632839 hydrochloride
    CAS: 157654-67-6
    纯度: >98.50%

    A deubiquitylase and deSUMOylase inhibitor

  • GC12484 structure
    GC12484BRD73954
    CAS: 1440209-96-0
    纯度: >98.00%

    A dual inhibitor of HDAC6 and HDAC8

  • GC12503 structure
    GC12503Pixantrone
    CAS: 144510-96-3

    A DNA topoisomerase II inhibitor