MTH1

MTH1(人MutT 同源物 1)

MTH1 (human MutT homolog 1) is an antimutagenic purine nucleoside triphosphatase that sanitize oxidized nucleotide pools. It protects the cell from oxidative stress-induced cell dysfunction or death. It is a target for anticancer treatment.

MTH1 相关产品(4)

  • GC13136 structure
    GC13136(S)-Crizotinib
    CAS: 1374356-45-2
    纯度: >99.50%

    An MTH1 inhibitor

  • GC12716 structure
    GC12716TH588
    CAS: 1609960-31-7
    纯度: >98.50%

    TH588是一种MTH1(NUDT1;IC 50 =5nM)抑制剂。

  • GC17601 structure
    GC17601TH287
    CAS: 1609960-30-6
    纯度: >98.00%

    A selective MTH1 inhibitor

  • GC17613 structure
    GC17613SCH 51344
    CAS: 171927-40-5

    An inhibitor of Ras/Rac transformation