DNA Damage/DNA Repair
DNA Damage/DNA Repair(DNA损伤/DNA修复)
- MTH1(4)
- PARP(124)
- ATM/ATR(29)
- DNA Alkylating(25)
- DNA Ligases(3)
- DNA Methyltransferase(32)
- DNA-PK(31)
- HDAC(182)
- Nucleoside Antimetabolite/Analogue(160)
- Telomerase(16)
- Topoisomerase(185)
- tankyrase(5)
- Antifolate(33)
- CDK(271)
- Checkpoint Kinase (Chk)(33)
- CRISPR/Cas9(9)
- Deubiquitinase(76)
- DNA Alkylator/Crosslinker(73)
- DNA/RNA Synthesis(473)
- Eukaryotic Initiation Factor (eIF)(27)
- IRE1(23)
- LIM Kinase (LIMK)(12)
- TOPK(6)
- Casein Kinase(48)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Poly(ADP-ribose) Glycohydrolase (PARG)(1)
- Early 2 Factor (E2F)(1)
DNA Damage/DNA Repair 相关产品(1788)
- GC17935PD 0332991 (Palbociclib) HClCAS: 827022-32-2纯度: >98.00% / >99.00%
PD 0332991 作为 CDK4 和 CDK6 激酶的口服活性强效和高选择性抑制剂，可以在低纳摩尔浓度下阻断 pRb 磷酸化并随后在敏感细胞系中诱导 G1 期停滞。
- GC18094Blasticidin S HClCAS: 3513-03-9纯度: >95.00% / >98.00% / >96.00% / >99.50%
Blasticidin S HCl是一种从灰色链霉菌中分离的核苷类抗生素。
- GC18354Bisindolylmaleimide X (hydrochloride)CAS: 145317-11-9纯度: >98.50% / >98.00%
Bisindolylmaleimide X (hydrochloride) 是一种新型的、具有细胞渗透性的蛋白激酶C（PKC）抑制剂。Bisindolylmaleimide X也可抑制细胞周期蛋白依赖性激酶2(CDK2)活性。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC17698 | SJB2-043 | 63388-44-3 | >99.00% | |
An inhibitor of the USP1-UAF1 complex and SARS-CoV-2 PL pro | ||||
| GC17716 | Oxaliplatin | 61825-94-3 | >98.00% / >99.50% | |
奥沙利铂（Oxaliplatin）是一种用于治疗癌症的细胞毒性化疗药物。 | ||||
| GC17750 | Raltitrexed | 112887-68-0 | >98.50% / >98.00% | |
An inhibitor of thymidylate synthase | ||||
| GC17833 | Topotecan | 123948-87-8 | >98.00% | |
Topotecan是一种毒药类的拓扑异构酶I抑制剂。 | ||||
| GC17837 | DMAT | 749234-11-5 | >98.00% | |
A cell-permeable inhibitor of CK2 | ||||
| GC17867 | Pyrimethamine | 58-14-0 | >99.50% | |
A dihydrofolate reductase inhibitor | ||||
| GC17897 | Triapine (3-AP) | 143621-35-6 | - | |
核糖核苷酸还原酶抑制剂 | ||||
| GC17935 | PD 0332991 (Palbociclib) HCl | 827022-32-2 | >98.00% / >99.00% | |
PD 0332991 作为 CDK4 和 CDK6 激酶的口服活性强效和高选择性抑制剂，可以在低纳摩尔浓度下阻断 pRb 磷酸化并随后在敏感细胞系中诱导 G1 期停滞。 | ||||
| GC18014 | Floxuridine | 50-91-9 | >99.50% | |
Floxuridine是一种抗代谢药物类抗癌药，是胸苷酸合酶的特异性抑制剂。 | ||||
| GC18028 | CVT-313 | 199986-75-9 | >99.50% | |
A Cdk2 inhibitor | ||||
| GC18053 | CCT241533 | 1262849-73-9 | - | |
A selective Chk2 inhibitor | ||||
| GC18094 | Blasticidin S HCl | 3513-03-9 | >95.00% / >98.00% / >96.00% / >99.50% | |
Blasticidin S HCl是一种从灰色链霉菌中分离的核苷类抗生素。 | ||||
| GC18100 | Illudin S | 1149-99-1 | >98.50% | |
A DNA alkylating agent | ||||
| GC18117 | XL413 | 1169558-38-6 | - | |
A potent inhibitor of Cdc7 | ||||
| GC18160 | USP7/USP47 inhibitor | 1247825-37-1 | >98.00% | |
A dual inhibitor of USP7 and USP47 | ||||
| GC18172 | E7449 | 1140964-99-3 | >98.00% | |
An inhibitor of PARP1, PARP2, and TNKS1/2 | ||||
| GC18186 | L67 | 325970-71-6 | >98.00% | |
A DNA ligase inhibitor | ||||
| GC18206 | WT161 | 1206731-57-8 | >98.50% | |
A potent inhibitor of HDAC6 | ||||
| GC18303 | MKC-3946 | 1093119-54-0 | >99.50% | |
An inhibitor of IRE1α | ||||
| GC18354 | Bisindolylmaleimide X (hydrochloride) | 145317-11-9 | >98.50% / >98.00% | |
Bisindolylmaleimide X (hydrochloride) 是一种新型的、具有细胞渗透性的蛋白激酶C（PKC）抑制剂。Bisindolylmaleimide X也可抑制细胞周期蛋白依赖性激酶2(CDK2)活性。 | ||||
| GC18396 | PD 407824 | 622864-54-4 | >98.00% | |
An inhibitor of Chk1 and WEE1 | ||||
| GC18402 | GSK3117391 | 1018673-42-1 | >98.50% | |
An HDAC inhibitor | ||||
| GC18404 | Lometrexol | 106400-81-1 | >98.00% / >97.50% | |
A GART inhibitor | ||||
| GC18426 | 8-Nitroguanine | 168701-80-2 | - | |
A mutagenic nitrative guanine derivative | ||||