MAPK Signaling
MAPK Signaling(MAPK信号通路)
MAPK Signaling 相关产品(575)
- GC48920β-Carboline-1-carboxylic AcidCAS: 26052-96-0纯度: >95.00%
An alkaloid with diverse biological activities
- GC49285Adenosine 5’-methylenediphosphate (hydrate)纯度: >98.00%
An inhibitor of ecto-5’-nucleotidase
- GC49686N-desmethyl Regorafenib N-oxideCAS: 835621-12-0纯度: >90.00%
An active metabolite of regorafenib
- GC60037A-3 hydrochlorideCAS: 78957-85-4纯度: >99.50%
A-3 hydrochloride, a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases, againsts cAMP-dependent protein kinase (PKA) (Ki=4.3 ?M), casein kinase II (CK2) (Ki=5.1 ?M) and myosin light chain kinase (MLCK) (Ki=7.4 ?M), also inhibits Protein Kinase C (PKC) and casein kinase I (CK1) with Ki values of 47 ?M and 80 ?M, respectively.
- GC60262N-FeruloyloctopamineCAS: 66648-44-0纯度: >98.00%
N-Feruloyloctopamine，从 Garlic 皮中分离出来的，是一种抗氧化剂成分。N-Feruloyloctopamine 显着降低 Akt 和 p38 MAPK 磷酸化水平。
- GC60393(-)-Zuonin ACAS: 84709-25-1纯度: >99.50%
(-)-ZuoninA(D-Epigalbacin)是一种天然木质素，是有效的、选择性的JNKs抑制剂，对JNK1、JNK2和JNK3作用的IC50值分别为1.7μM,2.9μM和1.74μM。
- GC60812ASTX029 (ERK1/2 inhibitor 2)CAS: 2095719-92-7纯度: >99.50%
ASTX029 (ERK1/2 inhibitor 2)是一种高效且选择性的具有口服生物利用活性的细胞外信号调节激酶（ERK）1/2抑制剂（对于ERK2的IC 50 为2.7nM）。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC48920 | β-Carboline-1-carboxylic Acid | 26052-96-0 | >95.00% | |
An alkaloid with diverse biological activities | ||||
| GC49150 | Tpl2 Kinase Inhibitor (hydrochloride) | - | >98.00% | |
A Tpl2 inhibitor | ||||
| GC49186 | O-Demethyl Apremilast | 1384441-38-6 | >95.00% | |
An active metabolite of apremilast | ||||
| GC49241 | Methyl Diethyldithiocarbamate | 686-07-7 | >95.00% | |
An active metabolite of disulfiram | ||||
| GC49265 | PKI (14-22) amide (myristoylated) (trifluoroacetate salt) | - | >98.00% | |
A PKA inhibitor | ||||
| GC49285 | Adenosine 5’-methylenediphosphate (hydrate) | - | >98.00% | |
An inhibitor of ecto-5’-nucleotidase | ||||
| GC49686 | N-desmethyl Regorafenib N-oxide | 835621-12-0 | >90.00% | |
An active metabolite of regorafenib | ||||
| GC49700 | Takeda-6d | 1125632-93-0 | >95.00% | |
A dual inhibitor of RAF kinases and VEGFR2 | ||||
| GC49763 | S6K-18 | 1265789-88-5 | >98.00% | |
A p70S6K1 inhibitor | ||||
| GC50181 | CW 008 | 1134613-19-6 | - | |
PKA signaling activator; promotes osteogenesis from hMSCs | ||||
| GC50252 | PF 06260933 dihydrochloride | - | - | |
MAP4K4 (HGK) inhibitor; also inhibits MINK and TNIK | ||||
| GC50294 | RMM 46 | 1307896-46-3 | - | |
An inhibitor of RSK2 | ||||
| GC50295 | TL4-12 | 1620820-12-3 | >98.50% | |
TL4 12 是一种有效的选择性 GCK（生发中心激酶）抑制剂。 | ||||
| GC50316 | Org 48762-0 | 755753-89-0 | - | |
Selective p38α/β inhibitor; orally bioavailable | ||||
| GC50400 | CC 401 dihydrochloride | 2250025-96-6 | - | |
A potent, specific pan-JNK inhibitor | ||||
| GC50406 | st-Ht31 | 188425-80-1 | - | |
Inhibits PKA/AKAP interactions; cell permeable | ||||
| GC50407 | st-Ht31 P | 252869-81-1 | - | |
Negative control for st-Ht31 | ||||
| GC50501 | STAD 2 | 1542100-77-5 | >98.00% | |
STAD 2 是 PKA-RII 的有效选择性破坏剂，Kd 为 6.2 nM。 | ||||
| GC50502 | RI-STAD 2 | - | - | |
AKAP disruptor; selectively binds PKA-RI with high affinity and blocks its interaction with AKAP; cell permeable | ||||
| GC60037 | A-3 hydrochloride | 78957-85-4 | >99.50% | |
A-3 hydrochloride, a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases, againsts cAMP-dependent protein kinase (PKA) (Ki=4.3 ?M), casein kinase II (CK2) (Ki=5.1 ?M) and myosin light chain kinase (MLCK) (Ki=7.4 ?M), also inhibits Protein Kinase C (PKC) and casein kinase I (CK1) with Ki values of 47 ?M and 80 ?M, respectively. | ||||
| GC60262 | N-Feruloyloctopamine | 66648-44-0 | >98.00% | |
N-Feruloyloctopamine，从 Garlic 皮中分离出来的，是一种抗氧化剂成分。N-Feruloyloctopamine 显着降低 Akt 和 p38 MAPK 磷酸化水平。 | ||||
| GC60393 | (-)-Zuonin A | 84709-25-1 | >99.50% | |
(-)-ZuoninA(D-Epigalbacin)是一种天然木质素，是有效的、选择性的JNKs抑制剂，对JNK1、JNK2和JNK3作用的IC50值分别为1.7μM,2.9μM和1.74μM。 | ||||
| GC60592 | APS6-45 | 2188236-41-9 | >99.50% | |
APS6-45(Compound 10) is an orally active tumor-calibrated inhibitor (TCI) that inhibits RAS/MAPK signaling and exhibits antitumor activity. | ||||
| GC60812 | ASTX029 (ERK1/2 inhibitor 2) | 2095719-92-7 | >99.50% | |
ASTX029 (ERK1/2 inhibitor 2)是一种高效且选择性的具有口服生物利用活性的细胞外信号调节激酶（ERK）1/2抑制剂（对于ERK2的IC 50 为2.7nM）。 | ||||