Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC36621 MK-0773

PF-05314882
MK-0773 是一种选择性雄激素受体调节剂 (selective androgen receptor modulators)，与 AR 结合，IC50 值为 6.6 nM。
GC14525 ML 190 ML 190 是一种选择性 κ 阿片受体 (KOR) 拮抗剂，IC50 分别为 120 nM 和 EC50 分别为 129 nM 。
GC44216 ML-180

SR1848
An inverse agonist of LRH-1
GC10212 MM 11253 A selective antagonist of RARγ
GC47698 Mometasone

莫米松-d3EP杂质G)
A synthetic glucocorticoid with anti-inflammatory and anti-allergic activities
GC18349 Motilin (porcine) A polypeptide hormone
GC47705 Mozavaptan-d6

OPC-31260-d6
A neuropeptide with diverse biological activities
GC11881 MPP dihydrochloride

MPP二盐酸盐
MPP dihydrochloride是一种选择性雌激素受体α（ERα）拮抗剂。
GC73494 MSU-42011 MSU-42011是一种口服活性类视黄醇X受体（RXR）激动剂。
GC70268 MT-7716 hydrochloride MT-7716 hydrochloride（W-212393盐酸盐）是一种选择性非肽伤害感受素受体（NOP）激动剂，有望成为预防酒精滥用和复发的潜在治疗药物。
GC49802 N-Acetyl-L-thyroxine

N-乙酰基L-甲状腺素
A thyroid hormone derivative
GC12663 N-Benzylnaltrindole hydrochloride δ2 opioid receptor antagonist
GC49399 N-Desbutyl Dronedarone (hydrochloride)

N-[2-丁基-3-[4-[3-(丁基氨基)丙氧基]苯甲酰基]-5-苯并呋喃基]甲磺酰胺盐酸盐,SR35021 hydrochloride
An active metabolite of dronedarone
GC32907 N-desmethyl Enzalutamide (N-desmethyl MDV 3100)

4-[3-[4-氰基-3-(三氟甲基)苯基]-5,5-二甲基-4-氧代-2-硫代-1-咪唑烷基]-2-氟苯甲酰胺,N-desmethyl MDV 3100
N-desMethyl EnzalutaMide (N-desmethyl MDV 3100) is the active metabolite of Enzalutamide, which is an oral androgen receptor inhibitor for treatment of castration-resistant prostate cancer.
GC16553 N-Desmethylclozapine

N-去甲基氯氮平; Norclozapine; Desmethylclozapine; Normethylclozapine
An active metabolite of clozapine
GC14979 N-MPPP Hydrochloride High affinity κ agonist
GC36778 N-terminally acetylated Leu-enkephalin

Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
N-terminally acetylated Leu-enkephalin 是N-末端乙酰化的 Leu-enkephalin。Leu-enkephalin是一种五氨基酸的内源性肽，作为阿片受体的激动剂。
GC44310 Nafarelin (acetate) A GNRH agonist
GC45997 Naftifine-d3 (hydrochloride)

盐酸萘替芬 d3 (盐酸盐)
An internal standard for the quantification of naftifine
GC31314 Nagilactone B

竹柏内酯 B

NagilactoneB，是从Podocarpusnagi根皮中提取的，是一种肝X受体(LXR)激动剂。
GC46182 Naldemedine

S-297995
Naldemedine (S-297995) 是一种口服有效的 μ-阿片受体拮抗剂 (PAMORA)。
GC71539 Naldemedine tosylate Naldemedine tosylate是一种口服活性μ阿片受体拮抗剂（PAMORA）。
GC44312 Nalfurafine

纳呋拉啡; TRK-820

纳呋法芬（TRK-820）是一种强效选择性口服活性G蛋白偏向kappa阿片受体（KOR）激动剂。
GC36689 Nalfurafine hydrochloride

盐酸纳呋拉啡; TRK-820 hydrochloride
An Analytical Reference Standard
GC30932 Naloxegol (NKTR-118)
Naloxegol(NKTR-118;AZ-13337019)是阿片受体拮抗剂。
GC30881 Naloxegol oxalate (NKTR-118 oxalate)

聚乙二醇纳诺醇

A peripherally acting antagonist of the μ-opioid receptor
GC16588 Naloxonazine dihydrochloride Naloxonazine dihydrochloride 是一种特异性的 μ-阿片受体拮抗剂，IC50 为 5.4 nM。
GC11807 Naloxone (hydrochloride)

盐酸纳洛酮
Naloxone (hydrochloride)是一种纯阿片受体拮抗剂。
GC63686 Naloxone methiodide Naloxone methiodide 是一种外周限制性、非选择性和竞争性阿片受体 (opioid receptor) 拮抗剂。Naloxone methiodide 不能穿透血脑屏障。
GC19865 Naltrexone Hydrochloride

盐酸纳曲酮, Trexan
An Analytical Reference Material
GC13688 Naltrindole hydrochloride

纳曲吲哚盐酸盐
A potent, selective δ-opioid receptor antagonist
GC64586 Nandrolone laurate

月桂酸诺龙
Nandrolone laurate 是一种雄激素合成代谢类固醇 (androgenic anabolic steroid)。Nandrolone laurate 增加心肌对缺血/再灌注损伤的易感性。Nandrolone laurate 增加运动后肌糖原的补充率。
GC63096 Nandrolone phenylpropionate

苯丙酸诺龙
Nandrolone phenylpropionate，19-nortestosterone 的衍生物，是一种合成代谢类固醇，可促进蛋白质合成。Nandrolone phenylpropionate 用于缓解组织分解代谢，可以用于骨质疏松症和特纳综合征的研究。
GC47747 Napyradiomycin A1 A fungal metabolite with diverse biological activities
GC69541 NDB NDB 是一种选择性人 FXRα (hFXRα) 拮抗剂，可有效调节 FXRα 下游基因的转录。NDB可用于抗糖尿病研究。
GC44363 Neoaureothin

NSC 260179, Spectinabilin
A bacterial metabolite
GC17200 Nestoron

醋酸烯诺孕酮; ST-1435; Elcometrine
A synthetic progestin
GC44375 Neuromedin C (trifluoroacetate salt)

GRP(18-27), NMC
A bombesin-like neuropeptide
GC44376 Neuromedin N (trifluoroacetate salt)

NMN
A neurotensin-like neuropeptide
GC15408 Neuropeptide AF (human)

神经肽AF（人类）,Neuropeptide AF (93-110), human
Neuropeptide AF（人）是一种内源性抗阿片肽。
GC47769 Neuropeptide S (human) (acetate)

NPS
A neuropeptide NSPR agonist
GC18277 Neuropeptide S (rat)

NPS
A neuropeptide NSPR agonist
GC63595 NH-3 NH-3 是一种具有口服活性的，可逆甲状腺激素受体 (THR) 拮抗剂，IC50 为 55 nM。NH-3 是选择性甲状腺素 GC-1 的衍生物，可抑制甲状腺激素与其受体的结合，并抑制辅因子募集。
GC34686 Nidufexor

LMB763

An FXR partial agonist
GC44405 Nilutamide

尼鲁米特,Nilandron; RU 23908
A non-steroidal androgen receptor antagonist
GC45760 Nilutamide-d6

尼鲁米特D6
An internal standard for the quantification of nilutamide
GC44446 NO-Losartan A A potent AT₁ receptor antagonist linked to an NO-donor
GC63115 Nociceptin (1-13), amide TFA Nociceptin (1-13), amide TFA 是一种有效的阿片受体 ORL1 (OP4) 受体激动剂，对小鼠输精管 pEC50 值为 7.9，与大鼠前脑膜结合的 Ki 值为 0.75 nM。
GC52189 Nomegestrol

诺美孕酮
A derivative of 19-norprogesterone
GC45529 Nonapeptide-1 (acetate)

Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2, MPFRWFKPV-NH2, 153N-6
An MC1R antagonist