Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC18301 Fadrozole (hydrochloride)
盐酸法倔唑,CGS 16949A; (Rac)-FAD286 hydrochloride
A non-steroidal aromatase inhibitor
GC18277 Neuropeptide S (rat)
NPS
A neuropeptide NSPR agonist
GC18270 22(S)-hydroxy Cholesterol
22(S)-羟基胆固醇,22β-hydroxy Cholesterol
A synthetic oxysterol and LXR modulator
GC18243 MGL-3196
MGL-3196; VIA-3196
MGL-3196是一种高选择性的口服甲状腺激素受体β（THRβ）激动剂，EC₅₀为0.21μM。
GC18231 Urocortin II (human) (trifluoroacetate salt) A neuropeptide hormone
GC18212 Cilofexor
GS-9674
An FXR ligand
GC18205 3,5-Diiodothyroacetic Acid
4-(4-羟基苯氧基)-3,5-二碘-苯基-乙酸
A thyroid hormone derivative
GC11807 Naloxone (hydrochloride)
盐酸纳洛酮
Naloxone (hydrochloride)是一种纯阿片受体拮抗剂。
GC10413 Thyroid Hormone Receptor Antagonist (1-850) Blocks T3 binding to the thyroid hormone receptor
GC10002 Coumestrol
拟雌内酯
A naturally-occurring phytoestrogen
GC13431 24α-methyl Cholesterol
菜油甾醇; (24R)-5-Ergosten-3β-ol
A phytosterol
GC17433 Phytol
植物醇; (E)?-?Phytol
A precursor of phytanic acid
GC10684 Zearalanone
玉米赤霉酮
A mycotoxin with estrogen-like effects
GC17588 Bavachin
补骨脂二氢黄酮; Corylifolin
A phytoestrogen
GC11425 Lasofoxifene (tartrate)
酒石酸拉索昔芬,CP 336,156
A selective estrogen receptor modulator
GC15483 Luffariellolide A natural inhibitor of several sPLA₂ isoforms
GC10384 3,3',5'-Triiodo-L-thyronine
碘塞罗宁,Reverse T3,rT3,3,3’,5’-T3
A thyroid hormone variant
GC11700 25(S)-27-hydroxy Cholesterol
(25S)-26-hydroxy cholesterol
An endogenous agonist for LXR
GC14638 SR9238 A liver-specific inverse agonist of LXR
GC16719 Ormeloxifene
苯并吡喃,Centchroman

estrogen receptor modulator
GC13917 4’-hydroxy Tamoxifen
4-羟基他莫昔芬; (Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen; (Z)-Afimoxifene
An active tamoxifen metabolite
GC17679 GSK2881078 A selective androgen receptor modulator
GC17119 8-Prenylnaringenin
8-异戊烯基柚皮素
A phytoestrogen
GC17160 2-hydroxy Flutamide
羟基氟他胺,Hydroxyniphtholide,SCH 16423
An active metabolite of the antiandrogen flutamide
GC12644 Quinestrol
炔雌醇环戊醚,Estrovis?,Ethynyl Estradiol-3-cyclopentyl ether,W 3566

A synthetic estrogen
GC15774 5α-dihydro-11-keto Testosterone
17BETA-羟基-5ALPHA-雄甾烷-3,11-二酮,5α-Androstane-3,11-dione-17β-ol,11-keto Dihydrotestosterone,17β-hydroxy-5α-Androstane-3,11-dione
An Analytical Reference Standard
GC17827 24(R)-hydroxy Cholesterol
24-Epicerebrosterol
A synthetic enantiomer of a brain-derived oxysterol
GC13887 25(R)-27-hydroxy Cholesterol
27-羟基胆固醇
25(R)-27-hydroxy Cholesterol是肝脏X受体（LXR）α和LXRβ的激动剂，EC₅₀值分别为0.085μM和0.071μM。
GC14511 All-trans Retinal
视黄醛,Retinaldehyde,Vitamin A aldehyde
All-trans Retinal 是一种具有活性的vitamin A aldehyde，对CRBP-I和CRBP-II蛋白的K_d值分别为50nM和90nM。
GC10785 Danazol
达那唑
An androgen receptor agonist
GC14596 9-cis-Retinoic Acid
9-顺式维甲酸,Alitretinoin
9-cis-Retinoic Acid是一种对视黄酸受体(RAR)具有高亲和力的配体，对RARα的EC₅₀值为0.2μM。
GC18076 24(S)-hydroxy Cholesterol
(3Β,24S)-胆甾-5-烯-3,24-二醇,Cerebrosterol
An agonist of LXR receptors
GC10663 Dihydrodaidzein
二氢大豆苷元; (±)-Dihydrodaidzein
An active metabolite of daidzein
GC11606 4-Methylbenzylidene camphor
4-甲基苄亚基樟脑; 4-MBC; Enzacamene
A UV blocker with estrogenic effects
GC17059 Acetyl Podocarpic Acid Anhydride
APD
An endogenous LXR agonist
GC12890 α-Naphthoflavone
α-萘黄酮
A flavone that modulates xenobiotic metabolism
GC11734 α-Zearalenol
ALPHA-玉米赤霉烯醇
A major hepatic metabolite of zearalenone
GC17161 Methylpiperidino pyrazole
MPP
Methylpiperidino pyrazole是一种对雌激素受体α（Erα）具有高度选择性的拮抗剂，其半数抑制浓度（IC₅₀）为20.01nM。
GC14221 HE-3235
Apoptone,17α-Ethynyl-5α-androstane-3α,17ß-diol
Androgen receptor antagonist
GC11957 RD162
N-甲基-4-[7-(4-氰基-3-三氟甲基苯基)-8-氧代-6-硫酮-5,7-二氮杂螺[3.4]辛烷-5-基]-2-氟苯甲酰胺
A second-generation androgen receptor antagonist
GC14972 22(R)-hydroxy Cholesterol
22(R)-羟基胆固醇,Narthesterol
22(R)-hydroxy Cholesterol是一种肝X受体（LXR）的内源性激动剂，其EC₅₀值为325nM。
GC14405 AZD9496
(E)-3-[3,5-二氟-4-[(1R,3R)-2-(2-氟-2-甲基丙基)-3-甲基-2,3,4,9-四氢-1H-吡啶并[3,4-B]吲哚-1-基]苯基]丙烯酸
A SERD
GC17803 4-Hydroxytamoxifen
(E/Z)-4-羟基他莫昔芬; Afimoxifene
4-hydroxytamoxifen 是他莫昔芬和选择性雌激素受体拮抗剂的主要代谢产物。
GC11837 MI-136 A menin-MLL inhibitor
GC10618 Fluoxymesterone
氟甲睾酮
An Analytical Reference Standard
GC15599 Hydroxyprogesterone caproate
己酸孕酮; 17α-Hydroxyprogesterone hexanoate; 17α-Hydroxyprogesterone caproate
A synthetic progestogen
GC11144 Chlormadinone acetate
醋酸氯地孕酮
A synthetic progestin
GC17475 17-Hydroxyprogesterone
17α-羟孕酮; 17-Hydroxyprogesterone; 17-OHP
A steroid and precursor in the synthesis of adrenal androgens
GC16631 EPI-001
双酚A
An androgen receptor antagonist
GC11386 ODM-201
达洛鲁胺,ODM-201; BAY-1841788
ODM-201是一种强效的雄激素受体拮抗剂，K_i值为11nM，IC₅₀值为26nM。