GlpBio

Ubiquitination/ Proteasome

Ubiquitination/ Proteasome(泛素化/蛋白酶体)

研究方向

Ubiquitination/ Proteasome 相关产品(1292)

  • GC15578 structure
    GC15578Dienogest
    CAS: 65928-58-7
    纯度: >98.00%

    A synthetic progestin and PR agonist

  • GC15588 structure
    GC15588PHA-848125
    CAS: 802539-81-7
    纯度: >99.50%

    An inhibitor of Cdks

  • GC15600 structure
    GC15600Erlotinib Hydrochloride
    CAS: 183319-69-9
    纯度: >99.50%

    An EGFR tyrosine kinase inhibitor

  • GC15605 structure
    GC15605Ezetimibe
    CAS: 163222-33-1
    纯度: >99.50% / >99.00%

    Ezetimibe是一种选择性胆固醇吸收抑制剂，对肺癌细胞(A549)和人胚肾细胞(HEK293)的IC 50 为50µM，对黑色素瘤细胞(A375)的IC 50 为30µM，作用时间均为48h。

  • GC15610 structure
    GC15610UNC0638
    CAS: 1255580-76-7
    纯度: >99.00%

    A G9a and GLP histone methyltransferase inhibitor

  • GC15617 structure
    GC15617Etoposide
    CAS: 33419-42-0
    纯度: >99.50% / >99.00% / >98.50%

    Etoposide（VP-16）是一种非特异性拓扑异构酶II（Topoisomerase II）抑制剂，IC 50 值为59.2 μM。

  • GC15618 structure
    GC15618Melatonin
    CAS: 73-31-4
    纯度: >99.00% / >98.50%

    An indoleamine neurohormone that entrains circadian rhythms

  • GC15632 structure
    GC15632YM-155 hydrochloride
    CAS: 355406-09-6

    A survivin inhibitor

  • GC15642 structure
    GC15642CHIR 99021 trihydrochloride
    CAS: 1782235-14-6
    纯度: >98.00%

    A selective GSK3 inhibitor

  • GC15654 structure
    GC15654SBI-0206965
    CAS: 1884220-36-3
    纯度: >99.00%

    SBI-0206965，这种嘧啶衍生物是一种高选择性的激酶ULK1抑制剂，IC 50 值为108nM。

  • GC15668 structure
    GC15668Meprednisone
    CAS: 1247-42-3
    纯度: >99.50%

    A corticosteroid

  • GC15680 structure
    GC15680Perifosine
    CAS: 157716-52-4
    纯度: >98.00%

    Perifosine 是 Akt 的抑制剂 。

  • GC15684 structure
    GC15684KB-R7943 mesylate
    CAS: 182004-65-5
    纯度: >98.50%

    An inhibitor of the reverse Na + /Ca 2+ exchanger

  • GC15706 structure
    GC15706Aspirin (Acetylsalicylic acid)
    CAS: 50-78-2
    纯度: >99.50%

    A non-selective, irreversible COX inhibitor

  • GC15725 structure
    GC15725PTC-209
    CAS: 315704-66-6
    纯度: >98.00%

    PTC-209 是一种小分子化合物，可选择性抑制 BMI-1，在 HT1080 细胞中的 IC50 为 0.5μM，是一种很有前途的抗癌药物在体外，PTC-209 以 0.1 到 10μM 之间的剂量处理人结直肠癌细胞，以剂量依赖性方式降低 BMI-1 蛋白水平，同时减少细胞生长。

  • GC15730 structure
    GC15730Kaempferide
    CAS: 491-54-3
    纯度: >98.00%

    A flavonoid with diverse biological activities

  • GC15736 structure
    GC15736Rosuvastatin Calcium
    CAS: 147098-20-2
    纯度: >99.50%

    Rosuvastatin Calcium是一种竞争性HMG-CoA还原酶抑制剂，IC 50 值为11nM。

  • GC15741 structure
    GC15741LY2603618
    CAS: 911222-45-2
    纯度: >98.00%

    A Chk1 inhibitor

  • GC15742 structure
    GC15742OSU-03012 (AR-12)
    CAS: 742112-33-0

    An anti-cancer celecoxib analog

  • GC15785 structure
    GC15785Saquinavir mesylate
    CAS: 149845-06-7
    纯度: >98.50%

    An HIV protease inhibitor

  • GC15794 structure
    GC15794Valproic acid sodium salt (Sodium valproate)
    CAS: 1069-66-5
    纯度: >98.00%

    Valproic acid sodium salt (Sodium valproate)（VPA）是一种具有口服活性的组蛋白脱乙酰酶 （HDAC）抑制剂，IC 50 值为1.5mM，抑制HDAC1的IC 50 值为400μM，同时可诱导HDAC2的降解。

  • GC15810 structure
    GC15810Clinofibrate
    CAS: 30299-08-2
    纯度: >99.50%

    A hypolipidemic agent

  • GC15814 structure
    GC15814Pamapimod (R-1503, Ro4402257)
    CAS: 449811-01-2
    纯度: >99.50%

    An orally bioavailable inhibitor of p38α MAP kinase

  • GC15818 structure
    GC15818RAF265
    CAS: 927880-90-8
    纯度: >99.50%

    A B-Raf and VEGFR2 inhibitor