GlpBio

Ubiquitination/ Proteasome

Ubiquitination/ Proteasome(泛素化/蛋白酶体)

研究方向

Ubiquitination/ Proteasome 相关产品(1292)

  • GC14920 structure
    GC14920VX-661
    CAS: 1152311-62-0
    纯度: >98.00%

    An investigational compound that promotes the maturation of delta F508 CFTR

  • GC14945 structure
    GC14945Sirtinol
    CAS: 410536-97-9
    纯度: >98.00%

    Inhibitor of sirtuin deacetylases

  • GC14961 structure
    GC14961Cytarabine hydrochloride
    CAS: 69-74-9
    纯度: >99.00%

    A nucleoside analog and prodrug form of ara-CTP

  • GC14968 structure
    GC14968Esmolol HCl
    CAS: 81161-17-3
    纯度: >99.00%

    A β 1 -AR antagonist

  • GC14969 structure
    GC14969Idarubicin HCl
    CAS: 57852-57-0
    纯度: >99.50%

    Idarubicin HCl是一种口服蒽环类抗白血病药物。

  • GC15002 structure
    GC15002Sodium Phenylbutyrate
    CAS: 1716-12-7
    纯度: >99.50%

    Sodium Phenylbutyrate是一种组蛋白去乙酰化酶（HDAC）抑制剂。

  • GC15004 structure
    GC15004URMC-099
    CAS: 1229582-33-5
    纯度: >99.50%

    URMC-099作为一种基于7-氮杂吲哚的MLK3抑制剂，其IC50为14 nM，可特异性影响参与疾病病理生物学的特定aβ物种。

  • GC15014 structure
    GC15014A-867744
    CAS: 1000279-69-5
    纯度: >99.50%

    A positive allosteric modulator of α7 nAChRs

  • GC15017 structure
    GC15017NSC 624206
    CAS: 13116-77-3

    An inhibitor of ubiquitin-activating enzyme (E1)

  • GC15022 structure
    GC15022Vandetanib (ZD6474)
    CAS: 443913-73-3
    纯度: >99.50%

    A multi-kinase inhibitor

  • GC15023 structure
    GC15023Telmisattan
    CAS: 144701-48-4
    纯度: >99.50%

    Selective angiotensin II receptor antagonist

  • GC15024 structure
    GC15024Nifedipine
    CAS: 21829-25-4
    纯度: >99.00% / >98.00%

    An L-type calcium channel blocker

  • GC15031 structure
    GC15031Rapamycin (Sirolimus)
    CAS: 53123-88-9
    纯度: >98.00% / >99.50%

    Rapamycin曾经被用作抗真菌抗生素。

  • GC15064 structure
    GC15064Purmorphamine
    CAS: 483367-10-8
    纯度: >99.50% / >98.00%

    Purmorphamine是第一个针对Smoothened蛋白开发的小分子激动剂, 能够直接结合并激活Smo,阻断BODIPY-cyclopamine与Smo结合。

  • GC15072 structure
    GC15072GSK2126458
    CAS: 1086062-66-9
    纯度: >99.50%

    A potent pan-PI3K and mTOR inhibitor

  • GC15077 structure
    GC15077SA 47
    CAS: 792236-07-8
    纯度: >99.00%

    SA 47 是一种选择性强效的脂肪酸酰胺水解酶 (FAAH) 和氨基甲酸酯抑制剂 。

  • GC15084 structure
    GC150842-Methoxyestradiol (2-MeOE2)
    CAS: 362-07-2
    纯度: >99.50% / >98.00%

    2-Methoxyestradiol (2-MeOE2/2-Me)是一种HIF-1α抑制剂。

  • GC15089 structure
    GC15089Carfilzomib (PR-171)
    CAS: 868540-17-4
    纯度: >99.00%

    A proteasome inhibitor

  • GC15094 structure
    GC15094LY2183240
    CAS: 874902-19-9
    纯度: >99.00%

    A potent, competitive inhibitor of anandamide uptake

  • GC15114 structure
    GC15114LAQ824 (NVP-LAQ824,Dacinostat)
    CAS: 404951-53-7
    纯度: >98.00%

    LAQ824 (NVP-LAQ824,Dacinostat)是一种新型、高效的组蛋白去乙酰化酶（HDAC）抑制剂，IC 50 为32nM。

  • GC15168 structure
    GC15168Urolithin A
    CAS: 1143-70-0
    纯度: >98.00%

    Urolithin A是由鞣花酸和鞣花单宁代谢产生的一种活性成分，可作为酪氨酸酶（IC 50 值为71.44±10.07µmol/L）和单胺氧化酶A（IC 50 值为29.41±9.01µmol/L）的强效抑制剂。

  • GC15184 structure
    GC15184Taurine
    CAS: 107-35-7
    纯度: >99.00%

    A sulfur-containing amino acid

  • GC15197 structure
    GC15197Saracatinib (AZD0530)
    CAS: 379231-04-6
    纯度: >99.50% / >99.00%

    A dual inhibitor of c-Src and Abl

  • GC15217 structure
    GC15217Danusertib (PHA-739358)
    CAS: 827318-97-8
    纯度: >98.50%

    A pan-Aurora kinase and Abl inhibitor