AMPK
AMPK(AMP活化蛋白激酶)
AMPK (5'AMP-activated protein kinase) acts as a metabolic master switch regulating several intracellular systems including the cellular uptake of glucose, the β-oxidation of fatty acids and the biogenesis of GLUT4 (glucose transporter 4) and mitochondria.
AMPK 相关产品(79)
- GC30056Danthron (Dantron)CAS: 117-10-2纯度: >98.50%
Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.
- GC31383Chitosan oligosaccharide COSCAS: 148411-57-8纯度: >98.00%
Chitosan oligosaccharide (COS) is an oligomer of β-(1?4)-linked d-glucosamine, of which actions involve the modulation of several important pathways including the suppression of nuclear factor kappa B (NF-κB) and mitogen-activated protein kinases (MAPK) and the activation of AMP-activated protein kinase (AMPK).
- GC33765Palmitelaidic Acid (9-trans-Hexadecenoic acid)CAS: 10030-73-6纯度: >99.00% / >98.00%
Palmitelaidic Acid (9-trans-Hexadecenoic acid)是palmitoleic acid的反式异构体，是一种在乳制品脂肪和各种部分氢化油中发现的膳食脂肪酸。
- GC351243α-HydroxymogrolCAS: 1343402-73-2纯度: >98.00%
3α-Hydroxymogrol 是从罗汉果中得到的三萜类化合物，为有效的 AMPK 激活剂，可增强 AMPK 的磷酸化水平。
- GC35327AMPK activator 1CAS: 1152423-98-7纯度: >98.50%
AMPK activator 1 是一种代表性的 AMPK 激活剂，EC50<0.1 μM。详细信息请参考专利文献 WO2013116491A1 中的化合物 No.1-75。
- GC38815Methyl cinnamateCAS: 103-26-4纯度: >99.00%
Methyl cinnamate, an active component of Zanthoxylum armatum, is a widely used natural flavor compound with antimicrobial and tyrosinase inhibitor activities. Methyl Cinnamate Inhibits Adipocyte Differentiation via Activation of the CaMKK2--AMPK Pathway in 3T3-L1 Preadipocytes.
- GC42776AmarogentinCAS: 21018-84-8纯度: >98.50%
Amarogentin是一种 Swertia 和 Gentiana 植物根中提取的裂环烯醚萜苷类天然产物，Amarogentin具有多种生物学活性，包括免疫调节、抗糖尿病和抗肿瘤。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC19269 | O-304 | 1261289-04-6 | >99.50% | |
A pan-activator of AMPK | ||||
| GC19286 | PF-06409577 | 1467057-23-3 | >99.00% | |
An AMPK activator | ||||
| GC25648 | MOTS-c | 1627580-64-6 | - | |
MOTS-c是一种线粒体衍生的具有代谢调节功能的多肽。 | ||||
| GC30056 | Danthron (Dantron) | 117-10-2 | >98.50% | |
Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes. | ||||
| GC31348 | 7-Methoxyisoflavone | 1621-56-3 | >99.50% | |
A synthetic isoflavone | ||||
| GC31361 | MK-3903 | 1219737-12-8 | >98.00% | |
An AMPK activator | ||||
| GC31383 | Chitosan oligosaccharide COS | 148411-57-8 | >98.00% | |
Chitosan oligosaccharide (COS) is an oligomer of β-(1?4)-linked d-glucosamine, of which actions involve the modulation of several important pathways including the suppression of nuclear factor kappa B (NF-κB) and mitogen-activated protein kinases (MAPK) and the activation of AMP-activated protein kinase (AMPK). | ||||
| GC31411 | EX229 | 1219739-36-2 | >98.00% | |
EX229是一种苯并咪唑衍生物，是一种有效的变构激动剂作用于AMP活化蛋白激酶（AMPK）。 | ||||
| GC31470 | MK8722 | 1394371-71-1 | >99.50% / >98.00% | |
MK8722是一种口服变构泛AMPK激活剂，能够调节葡萄糖稳态，EC 50 值在1-60nM范围内。 | ||||
| GC33765 | Palmitelaidic Acid (9-trans-Hexadecenoic acid) | 10030-73-6 | >99.00% / >98.00% | |
Palmitelaidic Acid (9-trans-Hexadecenoic acid)是palmitoleic acid的反式异构体，是一种在乳制品脂肪和各种部分氢化油中发现的膳食脂肪酸。 | ||||
| GC35124 | 3α-Hydroxymogrol | 1343402-73-2 | >98.00% | |
3α-Hydroxymogrol 是从罗汉果中得到的三萜类化合物，为有效的 AMPK 激活剂，可增强 AMPK 的磷酸化水平。 | ||||
| GC35327 | AMPK activator 1 | 1152423-98-7 | >98.50% | |
AMPK activator 1 是一种代表性的 AMPK 激活剂，EC50<0.1 μM。详细信息请参考专利文献 WO2013116491A1 中的化合物 No.1-75。 | ||||
| GC36178 | Gomisin J | 66280-25-9 | >99.00% | |
A lignan with diverse biological activities | ||||
| GC37694 | STO-609 | 52029-86-4 | >98.00% | |
STO-609是一种选择性且细胞可渗透的Ca²⁺/钙调蛋白依赖性蛋白激酶激酶（CaM-KK）抑制剂，对重组CaM-KKα和CaM-KKβ的K i 值分别为80ng/mL和15ng/mL。 | ||||
| GC37970 | ZLN024 | 723249-01-2 | - | |
An allosteric activator of AMPK | ||||
| GC38101 | Demethyleneberberine | 25459-91-0 | >98.00% | |
去亚甲基小檗碱(DMB)作为药用植物黄柏的天然活性成分，具有良好的生物活性。 | ||||
| GC38209 | Kahweol | 6894-43-5 | >99.50% | |
A natural diterpene with anti-inflammatory and antiangiogenic properties | ||||
| GC38422 | Euphorbiasteroid | 28649-59-4 | >99.50% | |
A tricyclic diterpene | ||||
| GC38567 | Nepodin | 3785-24-8 | >99.50% | |
A naphthol with diverse biological activities | ||||
| GC38679 | Urolithin B | 1139-83-9 | >99.50% | |
A metabolite of ellagic acid | ||||
| GC38815 | Methyl cinnamate | 103-26-4 | >99.00% | |
Methyl cinnamate, an active component of Zanthoxylum armatum, is a widely used natural flavor compound with antimicrobial and tyrosinase inhibitor activities. Methyl Cinnamate Inhibits Adipocyte Differentiation via Activation of the CaMKK2--AMPK Pathway in 3T3-L1 Preadipocytes. | ||||
| GC39377 | EB-3D | 1839150-63-8 | >98.50% | |
EB-3D is a potent and selective inhibitor of choline kinase α (ChoKα) with IC50 of 1 μM for ChoKα1. EB-3D induces deregulation of the AMPK-mTOR pathway and apoptosis in leukemia T-cells. | ||||
| GC42776 | Amarogentin | 21018-84-8 | >98.50% | |
Amarogentin是一种 Swertia 和 Gentiana 植物根中提取的裂环烯醚萜苷类天然产物，Amarogentin具有多种生物学活性，包括免疫调节、抗糖尿病和抗肿瘤。 | ||||
| GC42987 | Buformin (hydrochloride) | 1190-53-0 | >98.00% | |
An antihyperglycemic biguanide | ||||