Ferroptosis
Ferroptosis(铁死亡)
Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.
Ferroptosis 相关产品(193)
- GC30067Butylhydroxyanisole (Butylated hydroxyanisole)CAS: 25013-16-5纯度: >99.00%
丁基羟基茴香醚（Butylated hydroxyanisole）（Butylated hydroxyanisole）是一种抗氧化剂，用作食品添加剂防腐剂。
- GC30512Vatiquinone (EPI-743)CAS: 1213269-98-7纯度: >98.00%
A metabolite of α-tocotrienol with antioxidant and ferroptosis inhibitory activity
- GC30788L-Glutamic acid monosodium salt (Monosodium glutamate)CAS: 142-47-2纯度: >98.00% / >99.50%
L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
- GC32723CDDO-Im (RTA-403)CAS: 443104-02-7纯度: >98.00%
CDDO-Im (RTA-403)是一种合成三萜类化合物，通过与Kelch样ECH相关蛋白1（Keap1）结合抑制核因子E2相关因子（Nrf2）的降解，从而激活Nrf2信号通路并提高其蛋白水平。
- GC33023D,L-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine)CAS: 5072-26-4纯度: >98.00%
A γ-glutamylcysteine synthetase inhibitor
- GC33098L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine)CAS: 83730-53-4纯度: >98.00%
L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine)是一种谷胱甘肽合成抑制剂。
- GC34057TBHQ (tert-Butylhydroquinone)CAS: 1948-33-0纯度: >99.50%
TBHQ(tert-Butylhydroquinone)是一种强效的酚类抗氧化剂，能够减轻氧化应激和炎症反应。
- GC34058NADPH tetrasodium saltCAS: 2646-71-1纯度: >99.50% / >98.00%
NADPH tetrasodium salt是还原型烟酰胺腺嘌呤二核苷酸磷酸（NADPH）的一种钠盐形式，NADPH是细胞内必需的辅因子，充当电子供体。
- GC34980(E)-Ferulic acidCAS: 537-98-4纯度: >99.00%
Trans-ferulic acid is a potent activator of AMPKunder high glucose condition.
- GC35398Arteannuin BCAS: 50906-56-4纯度: >98.00%
A precursor to artemisinin with diverse biological activities
- GC35876DL-GlutamineCAS: 6899-04-3纯度: >98.00%
DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.
- GC36011Ethylenediaminetetraacetic acid trisodium saltCAS: 150-38-9纯度: >98.00%
Ethylenediaminetetraacetic acid (EDTA) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity.
- GC37664Sorafenib (D3)CAS: 1130115-44-4纯度: >99.00%
An internal standard for the quantification of sorafenib
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC30039 | FIN56 | 1083162-61-1 | >98.00% | |
FIN56 是一种新型的铁死亡诱导剂，它通过增加 GPX4 的降解来触发铁死亡 。 | ||||
| GC30067 | Butylhydroxyanisole (Butylated hydroxyanisole) | 25013-16-5 | >99.00% | |
丁基羟基茴香醚（Butylated hydroxyanisole）（Butylated hydroxyanisole）是一种抗氧化剂，用作食品添加剂防腐剂。 | ||||
| GC30512 | Vatiquinone (EPI-743) | 1213269-98-7 | >98.00% | |
A metabolite of α-tocotrienol with antioxidant and ferroptosis inhibitory activity | ||||
| GC30788 | L-Glutamic acid monosodium salt (Monosodium glutamate) | 142-47-2 | >98.00% / >99.50% | |
L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. | ||||
| GC31492 | Vildagliptin dihydrate (LAF237 dihydrate) | 2133364-01-7 | - | |
A DPP-4 inhibitor | ||||
| GC31940 | Docebenone (AA 861) | 80809-81-0 | >99.00% | |
A 5-LO inhibitor | ||||
| GC32237 | CIL56 | 300802-28-2 | - | |
An inducer of non-apoptotic cell death | ||||
| GC32723 | CDDO-Im (RTA-403) | 443104-02-7 | >98.00% | |
CDDO-Im (RTA-403)是一种合成三萜类化合物，通过与Kelch样ECH相关蛋白1（Keap1）结合抑制核因子E2相关因子（Nrf2）的降解，从而激活Nrf2信号通路并提高其蛋白水平。 | ||||
| GC33023 | D,L-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) | 5072-26-4 | >98.00% | |
A γ-glutamylcysteine synthetase inhibitor | ||||
| GC33098 | L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine) | 83730-53-4 | >98.00% | |
L-Buthionine-(S,R)-sulfoximine (L-Butionine sulfoximine)是一种谷胱甘肽合成抑制剂。 | ||||
| GC33469 | NADPH tetracyclohexanamine | 100929-71-3 | - | |
A reduced form of NADP + | ||||
| GC34057 | TBHQ (tert-Butylhydroquinone) | 1948-33-0 | >99.50% | |
TBHQ(tert-Butylhydroquinone)是一种强效的酚类抗氧化剂，能够减轻氧化应激和炎症反应。 | ||||
| GC34058 | NADPH tetrasodium salt | 2646-71-1 | >99.50% / >98.00% | |
NADPH tetrasodium salt是还原型烟酰胺腺嘌呤二核苷酸磷酸（NADPH）的一种钠盐形式，NADPH是细胞内必需的辅因子，充当电子供体。 | ||||
| GC34070 | Brusatol | 14907-98-3 | >98.00% | |
Brusatol是一种Nrf2抑制剂，由从鸦嘴茅中分离提取。 | ||||
| GC34939 | UAMC-3203 hydrochloride | 2271358-65-5 | >98.50% | |
A ferroptosis inhibitor | ||||
| GC34980 | (E)-Ferulic acid | 537-98-4 | >99.00% | |
Trans-ferulic acid is a potent activator of AMPKunder high glucose condition. | ||||
| GC35398 | Arteannuin B | 50906-56-4 | >98.00% | |
A precursor to artemisinin with diverse biological activities | ||||
| GC35399 | Artefenomel | 1029939-86-3 | >99.00% | |
An antimalarial agent | ||||
| GC35692 | Chrysosplenetin | 603-56-5 | >99.50% | |
A flavonoid with diverse biological activities | ||||
| GC35795 | D,L-Buthionine-(S,R)-sulfoximine hydrochloride | - | - | |
A γ-glutamylcysteine synthetase inhibitor | ||||
| GC35876 | DL-Glutamine | 6899-04-3 | >98.00% | |
DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. | ||||
| GC36011 | Ethylenediaminetetraacetic acid trisodium salt | 150-38-9 | >98.00% | |
Ethylenediaminetetraacetic acid (EDTA) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity. | ||||
| GC36926 | Piperazine Erastin | 1538593-71-3 | - | |
A ferroptosis inducer | ||||
| GC37664 | Sorafenib (D3) | 1130115-44-4 | >99.00% | |
An internal standard for the quantification of sorafenib | ||||