Ferroptosis
Ferroptosis(铁死亡)
Ferroptosis is a unique iron-dependent form of nonapoptotic cell death. It is triggered by oncogenic RAS-selective lethal small molecule erastin. Acitvation of ferroptosis lead to nonapoptotic destruction of cancer cells.
Ferroptosis 相关产品(193)
- GC37665Sorafenib (D4)CAS: 1207560-07-3
Sorafenib D4 (Bay 43-9006 D4) 是 Sorafenib 氘代化合物标准品。Sorafenib 是一种多激酶抑制剂，抑制 Raf-1，B-Raf 和 VEGFR-3 的 IC50 分别为6 nM，20 nM，22 nM。
- GC40226Curcumin-d6CAS: 1335198-02-1纯度: >99.00%
An internal standard for the quantification of curcumin
- GC40228Fluvastatin-d6 (sodium salt)纯度: >95.00%
An internal standard for the quantification of fluvastatin
- GC43297Coenzyme Q2CAS: 606-06-4纯度: >95.00%
A biosynthetic precursor to CoQ 10 and an inhibitor of mitochondrial complex I
- GC45792Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)CAS: 39916-28-4纯度: >95.00%
An inducer of ferroptosis
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC37665 | Sorafenib (D4) | 1207560-07-3 | - | |
Sorafenib D4 (Bay 43-9006 D4) 是 Sorafenib 氘代化合物标准品。Sorafenib 是一种多激酶抑制剂，抑制 Raf-1，B-Raf 和 VEGFR-3 的 IC50 分别为6 nM，20 nM，22 nM。 | ||||
| GC38429 | Dihydroartemisinic acid | 85031-59-0 | >99.00% | |
A precursor to artemisinin | ||||
| GC40193 | UAMC-3203 | 2271358-64-4 | >98.00% | |
A ferroptosis inhibitor | ||||
| GC40211 | Ferrostatin-1 Diyne | 2226204-90-4 | >98.00% | |
A ferroptosis inhibitor | ||||
| GC40226 | Curcumin-d6 | 1335198-02-1 | >99.00% | |
An internal standard for the quantification of curcumin | ||||
| GC40228 | Fluvastatin-d6 (sodium salt) | - | >95.00% | |
An internal standard for the quantification of fluvastatin | ||||
| GC40922 | SRS11-92 | 1467047-25-1 | >98.00% | |
A ferroptosis inhibitor | ||||
| GC41293 | Glutathione ethyl ester | 92614-59-0 | >95.00% | |
A cell-permeable derivative of glutathione | ||||
| GC42039 | 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC | 154436-51-8 | >98.00% | |
An oxidized phospholipid | ||||
| GC42040 | 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE | 947381-58-0 | >98.00% | |
An oxidized phospholipid | ||||
| GC42041 | 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC | 154436-48-3 | >98.00% | |
An oxidized phospholipid | ||||
| GC42042 | 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE | 154436-49-4 | >90.00% | |
An oxidized phospholipid | ||||
| GC42928 | BHT | 128-37-0 | >99.00% | |
A synthetic antioxidant | ||||
| GC43231 | Cerivastatin (sodium salt) | 143201-11-0 | >98.00% | |
An inhibitor of HMG-CoA reductase | ||||
| GC43297 | Coenzyme Q2 | 606-06-4 | >95.00% | |
A biosynthetic precursor to CoQ 10 and an inhibitor of mitochondrial complex I | ||||
| GC43329 | Cu-ATSM | 68341-09-3 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC43623 | Erastin2 | 1695533-44-8 | >98.00% | |
Erastin2 是一种有效的系统 xc 抑制剂和铁死亡诱导剂。 | ||||
| GC44214 | ML-162 | 1035072-16-2 | >99.50% | |
ML-162是一种可抑制谷胱甘肽过氧化物酶4（GPX4）的小分子化合物，IC 50 值为1.42μM。 | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
A PPARγ agonist | ||||
| GC44893 | Siramesine (fumarate) | 163630-79-3 | >98.00% | |
A selective σ 2 receptor agonist | ||||
| GC44947 | SRS16-86 | 1793052-96-6 | >98.00% | |
SRS16-86是一种第三代ferrostatin类铁死亡抑制剂。 | ||||
| GC45248 | (-)-FINO2 | 869298-31-7 | >98.00% | |
(-)-FINO2一种能够选择性激活铁死亡的有机过氧化物，用于研究铁死亡机制及抗肿瘤治疗 | ||||
| GC45764 | Ciclopirox-d11 (sodium salt) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45792 | Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III) | 39916-28-4 | >95.00% | |
An inducer of ferroptosis | ||||