Microbiology & Virology

Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.

LL-37, human is a 37-residue, amphipathic, cathelicidin-derived peptide, which exhibits a broad spectrum of antimicrobial activity.

Mupirocin Calcium (Pseudomonic acid A) is the calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens,which inhibits bacterial protein synthesis and is used as an antibiotic.

NK01-63 (Coronastat) is a potent inhibitor of the SARS-CoV-2 3CL protease, which is a critical drug target for small molecule COVID-19, given its likely druggability and essentiality in the viral maturation and replication cycle.

Olanexidine (OPB-2045, OPB-2045G) is a monobiguanide compound with bactericidal activity.

Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture.

OX02983 is a novel anthelmintic agent, actives against both egg and adult stages of Trichuris parasites, immobilising whipworm and reducing the ability of embryonated Trichuris muris eggs to establish infection in the mouse host.

Piperaquine phosphate is an orally active bisquinolone antimalarial drug.

Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.

Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R), a crystalline complex combining penicillin G with procaine, is a β-lactam antibiotic.

Proflavine (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria. It is a topical antiseptic used mainly in wound dressings.

Riamilovir (Triazavirin) is a broad-spectrum antiviral drug candidate, which can be used for potential application against the Coronavirus 2019-nCoV.

Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.

Sulfamethoxazole sodium is an antibiotic used for bacterial infections.

WAY-297407 is a bioactive compound.

WAY-383487 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.

Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.

Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.

9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.

Sudan I (C.I. Solvent Yellow 14) is an azo dye. It causes tumors in the liver or urinary bladder in rats, mice, and rabbits and may be a potential carcinogen for humans.

Coixol (6-Methoxy-2-benzoxazolinone)是一种从薏苡仁（ Coix lacryma-jobi ）中提取的多酚类化合物，具有抗肿瘤、抗炎和抗氧化活性。

An alkaloid with diverse biological activities