GlpBio

Filovirus

Filovirus(丝状病毒)

Filoviruses is amongst the most lethal of primate pathogens. Filoviruses cause lethal hemorrhagic fever in humans and nonhuman primates. The family Filoviridae includes two genera: Marburgvirus, comprising various strains of the Lake Victoria marburgvirus (MARV); and Ebolavirus (EBOVs), comprising four species including Sudan ebolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Ivory Coast ebolavirus (CIEBOV), and Reston ebolavirus (REBOV); and a tentative species Bundibugyo ebolavirus (BEBOV).

The infections typically affect multiple organs in the body and are often accompanied by hemorrhage (bleeding). Once the virus has been transmitted from an animal host to a human, it can then spread through person-to-person contact.

Filovirus 相关产品(13)

  • GC14314 structure
    GC14314Aloperine
    CAS: 56293-29-9
    纯度: >98.00%

    An alkaloid with diverse biological activities

  • GC32089 structure
    GC32089Galidesivir hydrochloride (BCX 4430 (hydrochloride))
    CAS: 222631-44-9
    纯度: >99.50%

    Galidesivir (BCX4430) hydrochloride 是一种腺苷类似物和直接作用的抗病毒剂，可破坏病毒 RNA 依赖性 RNA 聚合酶 (RdRp) 活性。

  • GC32092 structure
    GC32092Galidesivir (BCX 4430)
    CAS: 249503-25-1
    纯度: >98.00%

    Galidesivir (BCX 4430) (BCX4430) 是一种腺苷类似物和直接作用的抗病毒剂，可破坏病毒 RNA 依赖性 RNA 聚合酶 (RdRp) 活性。

  • GC43228 structure
    GC43228Cephaeline
    CAS: 483-17-0
    纯度: >98.00%

    An alkaloid with diverse biological activities

  • GC67627 structure
    GC676272'-Deoxy-5'-O-DMT-2'-fluorouridine
    CAS: 146954-74-7

    2'-Deoxy-5'-O-DMT-2'-fluorouridine 是一种核苷类似物，是 5'-O-DMTr-5-FUDR 的衍生物。2'-Deoxy-5'-O-DMT-2'-fluorouridine 具有有效的抗黄热病 (YFV) 活性。

  • GC72368 structure
    GC72368Ansuvimab
    CAS: 2375952-29-5
    纯度: >99.00%

    Ansuvimab（Ansuvimab-zyk）是一种重组人单克隆IgG1抗体，对扎伊尔埃博拉病毒具有抗病毒活性。

  • GC72370 structure
    GC72370Atoltivimab
    CAS: 2135632-29-8
    纯度: >98.00%

    Atoltivimab (REGN3470)或mativimab /odesivimab (Inmazeb)是美国食品和药物管理局(FDA)批准的首个针对扎伊尔埃博拉病毒(ebov)感染的单克隆抗体。

  • GC72421 structure
    GC72421Larcaviximab
    CAS: 1792982-56-9
    纯度: >96.00%

    Larcaviximab（c4G7-N）是一种IgG1κ抗埃博拉病毒糖蛋白嵌合单克隆抗体。

  • GC72425 structure
    GC72425Maftivimab
    CAS: 2135632-36-7
    纯度: >96.00%

    Maftivimab (REGN3470-3471-3479)是丝状病毒抑制剂，是美国食品和药物管理局(FDA)批准的药物。

  • GC72434 structure
    GC72434Odesivimab
    CAS: 2135632-30-1
    纯度: >99.00%

    Odesivimab是一种针对埃博拉病毒糖蛋白的人单克隆抗体，重组组氨酸标记的Makona株埃博拉病毒糖蛋白外结构域蛋白的KD值为7.74nM。

  • GC72436 structure
    GC72436Porgaviximab
    CAS: 1792982-55-8
    纯度: 98.00%

    Porgaviximab是一种单克隆抗体，可用于埃博拉感染研究。

  • GC72446 structure
    GC72446Cosfroviximab
    CAS: 1792982-57-0
    纯度: 95.00%

    Cosfroviximab（c13C6-FR1）是一种针对埃博拉病毒糖蛋白（EBOV-GP）的小鼠/人嵌合单克隆抗体。

  • GC72667 structure
    GC72667EBOV-IN-1
    CAS: 1335113-30-8
    纯度: >97.00%

    EBOV-IN-1（com 3.47）是金刚烷二肽哌嗪和埃博拉病毒（EBOV）抑制剂。