Autophagy

A PKA inhibitor

An inhibitor of LAT1

IITZ-01 是一种有效的溶酶体自噬抑制剂，具有单剂抗肿瘤活性，对 PI3Kγ 的 IC50 为 2.62 μM。

An FXR agonist

SBI-0640756 (SBI-756) 是 eIF4G1 的抑制剂，可破坏 eIF4F 复合物。

A VPS34 inhibitor

AZ304 是一种 ATP 竞争性双 BRAF 激酶抑制剂，有效抑制野生型 BRAF、V600E 突变型 BRAF 和野生型 CRAF，IC50 分别为 79 nM、38 nM 和 68 nM。 AZ304 对其他激酶也有显着影响，例如 p38 (IC50, 6 nM)、CSF1R (IC50, 35 nM)。抗肿瘤活性。

DC661是一种能够抑制棕榈酰蛋白硫酯酶1（PPT1）并有效抑制细胞自噬的小分子化合物，可作为抗溶酶体剂。

Adenosine 5′-diphosphoribose sodium是一种核苷酸衍生物，是Transient receptor potential melastatin 2 (TRPM2)激动剂，在细胞内多种代谢途径中发挥着重要作用。

肝素钠盐（MW 15kDa）（Sodium heparin (MW 15kDa)）是肝素的聚合物，分子量为15kDa。

MRT67307 is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. MRT67307 potently inhibits ULK1 and ULK2 and blocks autophagy.

MRT68921 HCl是一种强效的ULK1和ULK2双重抑制剂，对ULK1和ULK2的IC 50 值分别为2.9nM和1.1nM。

A diterpenoid with antioxidant and osteoprotective activities

Dantrolene sodium hemiheptahydrate (Dantrium) ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.

Danthron (Chrysazin, Antrapurol) functions in regulating glucose and lipid metabolism by activating AMPK. Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron used to be a laxativa and now is currently used as an antioxidant in synthetic lubricants, in the synthesis of experimental antitumor agents, as a fungicide and as an intermediate for making dyes.

A fluorescent marker for autophagic vacuoles

p38-α MAPK-IN-1 is an inhibitor of p38-α, with IC50 value of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.

Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.

硒代蛋氨酸（Seleno-DL-methionine）是一种天然存在的含硒氨基酸，是硒的常见天然食物来源。

Metofenazate (Methophenazine) 是一种选择性钙调蛋白抑制剂。

Cresol是一种有机化合物，是芳香族有机化合物广泛存在的天然及合成基团。

FAAH-IN-2是摘自专利WO/2008/100977A2中的FAAH抑制剂。

BPO-27racemate是有效的CFTR抑制剂，IC50值为8nM。