GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC38371 structure
    GC38371(S)-(-)-Phenylethanol
    CAS: 1445-91-6
    纯度: >99.50%

    (S)-(-)-1-Phenylethanol ((S)-1-Phenylethanol, (S)-(-)-Phenylethanol) is an enantiomer of 1-Phenylethanol with flavor properties.

  • GC38438 structure
    GC38438Synephrine
    CAS: 94-07-5
    纯度: >98.50%

    Synephrine (Oxedrine), a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.

  • GC38440 structure
    GC38440Guaiazulene
    CAS: 489-84-9
    纯度: >99.00%

    A sesquiterpene with diverse biological activities

  • GC38457 structure
    GC38457Lapaquistat
    CAS: 189059-71-0
    纯度: >99.50%

    Lapaquistat (T-91485) 是一种胆固醇生物合成 cholesterol biosynthesis 的抑制剂，是 TAK-475 的活性代谢产物。Lapaquistat 可以降低他汀类药物在降脂治疗中的肌毒性。

  • GC38552 structure
    GC38552Tetrahydrocortisol
    CAS: 53-02-1
    纯度: >97.00%

    An endogenous metabolite of cortisol

  • GC38556 structure
    GC385561-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine
    CAS: 76343-22-1
    纯度: >99.00%

    1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine 是一种内源性代谢产物。

  • GC38560 structure
    GC38560Oleoylcarnitine
    CAS: 38677-66-6
    纯度: >96.00%

    A long-chain acylcarnitine

  • GC38574 structure
    GC38574Cholesteryl arachidonate
    CAS: 604-34-2
    纯度: >98.00%

    A cholesterol ester

  • GC38587 structure
    GC38587H-Arg-Lys-OH TFA
    纯度: >98.00%

    H-Arg-Lys-OH TFA 是由 L-精氨酸和 L-赖氨酸残基形成的二肽。

  • GC38593 structure
    GC38593Ethyl glucuronide
    CAS: 17685-04-0
    纯度: >98.00%

    Ethyl glucuronide是乙醇的一种非挥发性、水溶性的直接代谢物，可在体液、组织和毛发中检测到。

  • GC38638 structure
    GC38638Euphol
    CAS: 514-47-6
    纯度: >98.00%

    真酚(Euphol)是Euphorbia tirucalli中的主要成分,真酚可逆的抑制丝氨酸水解酶MGL活性(IC50 = 315 nM)。

  • GC38644 structure
    GC38644Glycodeoxycholic Acid
    CAS: 360-65-6
    纯度: >98.00%

    Glycodeoxycholic Acid是脱氧胆酸的甘氨酸结合形式。

  • GC38654 structure
    GC38654Bis(2-ethylhexyl) phthalate
    CAS: 117-81-7
    纯度: >99.00%

    Bis(2-ethylhexyl) phthalate，通常称为DEHP，是一种合成化合物，主要用作增塑剂。接触Bis(2-ethylhexyl) phthalate会对生物体产生各种不良影响，如生殖和发育受损、癌症、代谢改变以及神经和行为障碍。

  • GC38669 structure
    GC386693-Hydroxybenzoic acid
    CAS: 99-06-9

    3-Hydroxybenzoic acid 是一种内源性代谢产物。

  • GC38670 structure
    GC386701-Hydroxyoctadecane
    CAS: 112-92-5
    纯度: >98.00%

    1-Hydroxyoctadecane 是一种内源性代谢产物。

  • GC38684 structure
    GC38684(E)-m-Coumaric acid
    CAS: 14755-02-3
    纯度: >99.50%

    3-hydroxycinnamic acid (meta-Coumaric acid, m-Coumaric acid, m-Coumarate) is an aromatic acid that can be found in vinegar.

  • GC38688 structure
    GC38688Inosine 5'-monophosphate disodium salt (hydrate)
    CAS: 352195-40-5
    纯度: >99.50%

    Disodium 5'-inosinate monohydrate (Inosine 5'-monophosphate disodium salt hydrate) is an endogenous metabolite.

  • GC38689 structure
    GC38689Poly(4-vinylphenol)
    CAS: 24979-70-2
    纯度: >99.00%

    Poly(4-vinylphenol) 是一种内源性代谢产物。

  • GC38690 structure
    GC38690D-Glucuronic acid lactone
    CAS: 32449-92-6
    纯度: >98.00%

    D-Glucurone is a glucuronic acid derivative that is used for treating canine hepatitis.

  • GC38700 structure
    GC38700D-Arabinose
    CAS: 28697-53-2
    纯度: >98.00%

    A monosaccharide

  • GC38703 structure
    GC38703NSC 8751
    CAS: 107-93-7
    纯度: >99.50%

    NSC 8751 是一种内源性代谢产物。

  • GC38729 structure
    GC387292,5-Dimethylpyrazine
    CAS: 123-32-0
    纯度: >99.50%

    2,5-Dimethylpyrazine (NSC 49139) is an endogenous metabolite.

  • GC38734 structure
    GC38734Allotetrahydrocortisol
    CAS: 302-91-0
    纯度: >98.00%

    Allotetrahydrocortisol (5a-Tetrahydrocortisol) 是一种皮质醇的代谢产物。Cortisol 是皮质醇是人体主要的糖皮质激素，在肾上腺皮质产生，在许多生理过程中起着至关重要的作用。

  • GC38761 structure
    GC38761Cyclo(his-pro) TFA
    CAS: 936749-56-3
    纯度: >99.00%

    Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) 是一种具有口服活性的，结构上与促甲状腺激素释放激素相关的环状二肽。Cyclo(his-pro) TFA 可以抑制 NF-κB 核积累。Cyclo(his-pro) TFA 可以穿越脑血屏障并影响多种炎症和应激反应。