Endogenous Metabolite
Endogenous Metabolite(内源性代谢物)
Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Endogenous Metabolite 相关产品(1712)
- GC38299(2-Aminoethyl)phosphonic acidCAS: 2041-14-7
2-Aminoethylphosphonic acid (2-AEP, (2-Aminoethyl)phosphonic acid) is a type of abundant and ubiquitous naturally occurring phosphonate used as sources of phosphorus by many prokaryotic lineages.
- GC38300Phytic acid potassiumCAS: 129832-03-7纯度: >98.00%
Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM.
- GC38320L-Methionine sulfoxideCAS: 3226-65-1纯度: >99.50%
L-Methionine sulfoxide (H-Met(O)-OH),甲硫氨酸的代谢产物,诱导 M1/classical 巨噬细胞极化,并调节氧化应激和嘌呤能的信号传递参数。
- GC38323Tetrahydro-2H-pyran-2-oneCAS: 542-28-9纯度: >99.50%
δ-Valerolactone (Tetrahydro-2H-pyran-2-one, 5-Valerolactone, oxan-2-one) is an endogenous metabolite.
- GC38327Sodium 1-hydroxypropane-1,2,3-tricarboxylate hydrateCAS: 1637-73-6纯度: >97.00%
Sodium 1-hydroxypropane-1,2,3-tricarboxylate hydrate是三羧酸循环(TCA Cycle)中的关键中间产物,能够作为反应底物测定Isocitrate Dehydrogenase的活性
- GC38356Imidazoleacetic acid hydrochlorideCAS: 3251-69-2纯度: >99.00%
Imidazole-4(5)-acetic Acid Hydrochloride is a competitive antagonist at GABAC receptors.
- GC383591H-pyrazoleCAS: 288-13-1
Pyrazole (1H-pyrazole) is a five membered heteroaromatic ring with two nitrogen atoms is of immense significance. Pyrazole is an indispensable anchor for design and development of new pharmacological agents.
- GC383603-Methylbut-2-enoic acidCAS: 541-47-9
Senecioic acid (3-Methylcrotonic acid, 3,3-Dimethylacrylic acid, β-Methylcrotonic Acid) is an unsaturated fatty acid found in the pheromones of mealybug species and appears in the urine of patients with 3-Methylcrotonic aciduria.
- GC38363(R)-pyrrolidine-2-carboxylic acidCAS: 344-25-2
D-proline is an isomer of the naturally occurring amino acid, L-Proline.
- GC383672,4-Dihydroxypyrimidine-5-carboxylic AcidCAS: 23945-44-0
2,4-Dihydroxypyrimidine-5-carboxylic Acid (Uracil 5-carboxylic acid, Isoorotic acid, 5-Carboxyuracil) is an endogenous metabolite.
- GC383683-Furanoic acidCAS: 488-93-7纯度: >98.00%
3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals.
- GC38370N-Acetyl-L-leucineCAS: 1188-21-2纯度: >99.00%
N-acetyl-L-leucine is an active endogenous metabolite that accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC38298 | Pteridine-2,4(1H,3H)-dione | 487-21-8 | >99.50% | |
Pteridine-2,4(1H,3H)-dione 是一种内源性代谢产物。 | ||||
| GC38299 | (2-Aminoethyl)phosphonic acid | 2041-14-7 | - | |
2-Aminoethylphosphonic acid (2-AEP, (2-Aminoethyl)phosphonic acid) is a type of abundant and ubiquitous naturally occurring phosphonate used as sources of phosphorus by many prokaryotic lineages. | ||||
| GC38300 | Phytic acid potassium | 129832-03-7 | >98.00% | |
Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM. | ||||
| GC38301 | 2-(1H-Indol-3-yl)ethan-1-ol | 526-55-6 | - | |
An indole with diverse biological activities | ||||
| GC38317 | Acetamide | 60-35-5 | - | |
Acetamide (ethanamide, Acetic acid amide) is an organic compound that can be used as a plasticizer and an industrial solvent. | ||||
| GC38320 | L-Methionine sulfoxide | 3226-65-1 | >99.50% | |
L-Methionine sulfoxide (H-Met(O)-OH),甲硫氨酸的代谢产物,诱导 M1/classical 巨噬细胞极化,并调节氧化应激和嘌呤能的信号传递参数。 | ||||
| GC38321 | 2-Aminopyrimidin-5-ol | 143489-45-6 | >99.00% | |
2-Aminopyrimidin-5-ol 是一种内源性代谢产物。 | ||||
| GC38323 | Tetrahydro-2H-pyran-2-one | 542-28-9 | >99.50% | |
δ-Valerolactone (Tetrahydro-2H-pyran-2-one, 5-Valerolactone, oxan-2-one) is an endogenous metabolite. | ||||
| GC38324 | D-Galacturonic acid (hydrate) | 91510-62-2 | >98.00% | |
A monosaccharide | ||||
| GC38325 | N-Acetyl-D-mannosamine monohydrate | 7772-94-3 | - | |
A precusor of sialic acid | ||||
| GC38326 | NSC 13138 | 486-74-8 | >98.00% | |
Quinoline-4-carboxylic acid (4-Carboxyquinoline) is a very important structure in a synthetic medicinal chemistry. | ||||
| GC38327 | Sodium 1-hydroxypropane-1,2,3-tricarboxylate hydrate | 1637-73-6 | >97.00% | |
Sodium 1-hydroxypropane-1,2,3-tricarboxylate hydrate是三羧酸循环(TCA Cycle)中的关键中间产物,能够作为反应底物测定Isocitrate Dehydrogenase的活性 | ||||
| GC38356 | Imidazoleacetic acid hydrochloride | 3251-69-2 | >99.00% | |
Imidazole-4(5)-acetic Acid Hydrochloride is a competitive antagonist at GABAC receptors. | ||||
| GC38358 | 5'-Cytidylic acid | 63-37-6 | - | |
A pyrimidine nucleotide | ||||
| GC38359 | 1H-pyrazole | 288-13-1 | - | |
Pyrazole (1H-pyrazole) is a five membered heteroaromatic ring with two nitrogen atoms is of immense significance. Pyrazole is an indispensable anchor for design and development of new pharmacological agents. | ||||
| GC38360 | 3-Methylbut-2-enoic acid | 541-47-9 | - | |
Senecioic acid (3-Methylcrotonic acid, 3,3-Dimethylacrylic acid, β-Methylcrotonic Acid) is an unsaturated fatty acid found in the pheromones of mealybug species and appears in the urine of patients with 3-Methylcrotonic aciduria. | ||||
| GC38362 | KSD 2405 | 620-24-6 | >98.00% | |
3-Hydroxybenzyl alcohol is used as an intermediate to produce other chemicals. | ||||
| GC38363 | (R)-pyrrolidine-2-carboxylic acid | 344-25-2 | - | |
D-proline is an isomer of the naturally occurring amino acid, L-Proline. | ||||
| GC38364 | (R)-Ornithine hydrochloride | 16682-12-5 | >98.00% | |
An enantiomer of L-ornithine | ||||
| GC38366 | Pyridoxylamine dihydrochloride | 524-36-7 | >99.50% | |
A 4-methylamine form of vitamin B 6 | ||||
| GC38367 | 2,4-Dihydroxypyrimidine-5-carboxylic Acid | 23945-44-0 | - | |
2,4-Dihydroxypyrimidine-5-carboxylic Acid (Uracil 5-carboxylic acid, Isoorotic acid, 5-Carboxyuracil) is an endogenous metabolite. | ||||
| GC38368 | 3-Furanoic acid | 488-93-7 | >98.00% | |
3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals. | ||||
| GC38369 | (±)-Leucine | 328-39-2 | >98.00% | |
(±)-Leucine 是一种内源性代谢产物。 | ||||
| GC38370 | N-Acetyl-L-leucine | 1188-21-2 | >99.00% | |
N-acetyl-L-leucine is an active endogenous metabolite that accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus. | ||||
