D-Arabinose is a monosaccharide. It has been found in the O-specific polysaccharide of LPS in P. maltophilia.1 D-Arabinose (50 and 100 mM) inhibits S. oralis, F. nucleatum, and P. gingivalis biofilm formation as well as the activity of autoinducer 2, a quorum-sensing molecule involved in the pathogenesis of periodontitis, in V. harveyi in a reporter assay.2 It reduces the growth of C. elegans (IC50 = 7.5 mM), an effect that can be reversed by D-ribose or D-fructose, but not D-glucose.3
1.Wilkinson, S.G., Galbraith, L., and Anderton, W.J.Lipopolysaccharides from Pseudomonas maltophilia: Composition of the lipopolysaccharide and structure of the side-chain polysaccharide from strain N.C.I.B. 9204Carbohydr. Res.112(2)241-252(1983) 2.An, S.-J., Namkung, J.-U., Ha, K.-W., et al.Inhibitory effect of ?-arabinose on oral bacteria biofilm formation on titanium discsAnaerobe102533(2022) 3.Sakoguchi, H., Yoshihara, A., Shintani, T., et al.Growth inhibitory effect of ?-arabinose against the nematode Caenorhabditis elegans: Discovery of a novel bioactive monosaccharideBioorg. Med. Chem. Lett.26(3)726-729(2106)