PPAR
PPAR(过氧化物酶体增殖剂激活受体)
The peroxisome proliferator-activated receptors (PPARs), belonging to the nuclear receptor superfamily, are a group of nuclear receptor proteins that are composed of three isoforms, including PPARγ, PPARα and PPARδ, encoded by separate genes. PPARs have a modular structure characterized by the presence of two highly conserved domains, including the DNA binding domain (DBD) of two zinc fingers and the ligand binding domain (LBD) of 13 α-helices and a small 4-stranded β-sheet. PPARs are ligand-regulated transcription factors controlling gene expression by binding to specific response elements (PPREs) within promoters, where PPARs bind as heterodimers with a retinoid X receptor and interact with cofactors upon binding leading to the increasing of rate of transcription initiation.
PPAR 相关产品(215)
- GC45726Bezafibrate-d4CAS: 1189452-53-6纯度: >99.00%
An internal standard for the quantification of bezafibrate
- GC45829Troglitazone-d4纯度: >99.00%
Troglitazone-d4 是氘标记的曲格列酮。 Troglitazone 是一种 PPARγ 激动剂，对人和鼠 PPARγ 受体的 EC50 分别为 550 nM 和 780 nM。
- GC45921(±)8(9)-EET-d11 methyl ester纯度: >99.00%
A neuropeptide with diverse biological activities
- GC45981Pristanic Acid-d3CAS: 1383920-14-6纯度: >99.00%
An internal standard for the quantification of pristanic acid
- GC4644315-deoxy-δ12,14-Prostaglandin D2-d4CAS: 2750534-91-7纯度: >99.00%
A neuropeptide with diverse biological activities
- GC4644415-deoxy-δ12,14-Prostaglandin D2-d9CAS: 2738376-68-4纯度: >99.00%
A neuropeptide with diverse biological activities
- GC4644715-deoxy-δ12,14-Prostaglandin J2-d4CAS: 1542166-82-4纯度: >99.00%
An internal standard for the quantification of 15-deoxy-Δ 12,14 -prostaglandin J 2
- GC4644815-deoxy-δ12,14-Prostaglandin J2-d9纯度: >99.00%
A neuropeptide with diverse biological activities
- GC467579(Z),11(E)-Conjugated Linoleic Acid (sodium salt)CAS: 756499-04-4纯度: >98.00%
An isomer of linoleic acid
- GC47337Fenofibrate-d6CAS: 1092484-56-4纯度: >99.00%
An internal standard for the quantification of fenofibrate
- GC47397Gemfibrozil-d6CAS: 1184986-45-5纯度: >99.00%
An internal standard for the quantification of gemfibrozil
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC43800 | GW 9578 | 247923-29-1 | >98.00% | |
A potent, selective PPARα agonist | ||||
| GC43880 | Hydroxy Pioglitazone | 146062-44-4 | >95.00% | |
A major metabolite of pioglitazone | ||||
| GC44191 | MHY908 | 1393371-39-5 | >98.00% | |
A PPARα and PPARγ dual agonist | ||||
| GC44645 | Pioglitazone (potassium salt) | 1266523-09-4 | >98.00% | |
A PPARγ agonist | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
A PPARγ agonist | ||||
| GC45186 | ZLN005 (hydrochloride) | - | >98.00% | |
A small molecule activator of PGC-1α expression | ||||
| GC45506 | MD001 | 2254605-76-8 | >90.00% | |
A dual agonist of PPARα and PPARγ | ||||
| GC45566 | SR 16832 | 2088135-12-8 | >98.00% | |
A dual-site covalent antagonist of PPARγ | ||||
| GC45567 | SR 1903 | 1414248-06-8 | >98.00% | |
A modulator of RORγ and LXR receptors | ||||
| GC45726 | Bezafibrate-d4 | 1189452-53-6 | >99.00% | |
An internal standard for the quantification of bezafibrate | ||||
| GC45829 | Troglitazone-d4 | - | >99.00% | |
Troglitazone-d4 是氘标记的曲格列酮。 Troglitazone 是一种 PPARγ 激动剂，对人和鼠 PPARγ 受体的 EC50 分别为 550 nM 和 780 nM。 | ||||
| GC45921 | (±)8(9)-EET-d11 methyl ester | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC45981 | Pristanic Acid-d3 | 1383920-14-6 | >99.00% | |
An internal standard for the quantification of pristanic acid | ||||
| GC46264 | (±)8(9)-EET-d11 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46365 | 1,1'-(Azodicarbonyl)dipiperidine | 10465-81-3 | >97.00% | |
A Mitsunobu reagent | ||||
| GC46443 | 15-deoxy-δ12,14-Prostaglandin D2-d4 | 2750534-91-7 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46444 | 15-deoxy-δ12,14-Prostaglandin D2-d9 | 2738376-68-4 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46447 | 15-deoxy-δ12,14-Prostaglandin J2-d4 | 1542166-82-4 | >99.00% | |
An internal standard for the quantification of 15-deoxy-Δ 12,14 -prostaglandin J 2 | ||||
| GC46448 | 15-deoxy-δ12,14-Prostaglandin J2-d9 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46757 | 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) | 756499-04-4 | >98.00% | |
An isomer of linoleic acid | ||||
| GC47063 | CAY10767 | 2376590-40-6 | >98.00% | |
A PPARα agonist | ||||
| GC47337 | Fenofibrate-d6 | 1092484-56-4 | >99.00% | |
An internal standard for the quantification of fenofibrate | ||||
| GC47397 | Gemfibrozil-d6 | 1184986-45-5 | >99.00% | |
An internal standard for the quantification of gemfibrozil | ||||
| GC47417 | GW 9662-d5 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||